Pain, Postoperative clinical trials

The registry lists 5,640 studies for Pain, Postoperative across more than 10 countries. 1,230 are recruiting or about to start. 4,498 of them are mainly about Pain, Postoperative (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Phantom Limb too: 5,798 studies, 1,264 open.

ClinicalTrials.gov finds 8,170 studies for Pain, Postoperative. How that becomes 5,628 here

This page counts the studies the registry files under Pain, Postoperative, and those it files under no condition that list Pain, Postoperativethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

8,170Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
−154Filed under a narrower condition, counted on its own pagePhantom Limb 154
−79List Pain, Postoperative as a condition, but the registry did not file them under itMost often written as “Postoperative Pain Management” (36), “Post Operative Pain Control” (5), and “Postoperative Pain Control” (5). The registry filed them under other conditions only, most often Pain (21) and Agnosia (20).
−2,309Match it another way1,224 name it in the title, 81 in a keyword, and 1,004 by a synonym or other text the search reads.
5,628The count on this page166 of them list Pain, Postoperative in their own words; the registry filed them under no condition.

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Status

Completed: 3,237
Recruiting: 679
Status unknown: 669
Not yet recruiting: 481
Terminated: 214
Active, not recruiting: 144

Phase

Phase 4: 1,073
Phase 3: 460
Phase 2: 416
Phase 1: 130
Early Phase 1: 53

Where

United States: 1,180
Turkey: 1,092
Egypt: 595
China: 248
Canada: 190
Denmark: 180

Who runs them

Cairo University (132) · Assiut University (108) · Ain Shams University (102) · Tanta University (38) · Seoul National University Hospital (36) · Cukurova University (33) · Ataturk University (33) · Istanbul University (30)

What is being tested here

Drugs under test in Pain, Postoperative studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Bupivacaine	53	51	350
Dexmedetomidine	33	21	129
Dexamethasone	27	19	147
Ropivacaine	18	23	179
Morphine	17	11	93
Suzetrigine	16	4	17
Liposomal Bupivacaine	13	15	85
Lidocaine	12	24	112
Acetaminophen	10	23	116
Ketorolac	9	15	67

Drug classes tested here Local anesthetics 85 open · Opioids 52 open · Corticosteroids 33 open · NSAIDs 22 open · COX-2 inhibitors 5 open

Coming up

72phase 3 studies under way

525studies finish main data collection within a year25 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Nov 2026Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy · Phase 3 · Assiut University
Nov 2026Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial · Phase 3 · Oman Ministry of Health
Dec 2026RADA16 for Adult Tonsillectomy · Phase 3 · Rutgers, The State University of New Jersey
Dec 2026Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery · Phase 3 · Icahn School of Medicine at Mount Sinai
Dec 2026Methadone in TKA for Post-op Pain and Opioid Reduction · Phase 3 · Medical University of South Carolina
Dec 2026Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery. · Phase 3 · Children's Cancer Hospital Egypt 57357
Dec 2026Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY) · Phase 3 · Alexandre P. Joosten
Dec 2026Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression · Phase 3 · Hospital for Special Surgery, New York
Dec 2026Post-Op Pain Control for Prophylactic Intramedullary Nailing. · Phase 3 · St. Louis University
Dec 2026Methadone in THA for Post-op Pain and Opioid Reduction · Phase 3 · Medical University of South Carolina

Who these studies take

Of the 679 Pain, Postoperative studies recruiting now, 241 (35%) set no upper age limit and 328 (48%) stop at 75 or younger. 74 (11%) take children under 18. 90 (13%) are for women only and 9 (1%) for men only; 128 (19%) take healthy volunteers.

Recruiting studies that take each age, of 679
Age	Women	Men
10	39 (6%)	37 (5%)
18	546 (80%)	478 (70%)
30	597 (88%)	516 (76%)
40	598 (88%)	517 (76%)
50	574 (85%)	506 (75%)
65	529 (78%)	469 (69%)
75	397 (58%)	357 (53%)
85	289 (43%)	260 (38%)

Across all 5,640 studies, recruiting or not: 50% stop at 75 or younger and 38% at 65; 13% take children; 16% are for women only and 2% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Pain, Postoperative studies take

Of 541 phase 4 interventional studies under Pain, Postoperative, half reached primary completion within 16 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Phase 1	16 mo6–27 · 83 studies	—	18 mo8–30 · 65 studies
Phase 2	12 mo6–24 · 140 studies	7 mo3–11 · 49 studies	19 mo9–33 · 91 studies
Phase 2/3	17 mo10–41 · 52 studies	—	17 mo11–41 · 49 studies
Phase 3	17 mo8–30 · 166 studies	13 mo6–19 · 43 studies	20 mo10–38 · 123 studies
Phase 4	16 mo8–32 · 541 studies	—	16 mo8–32 · 531 studies
Interventional, no phase	11 mo6–23 · 2,102 studies	—	11 mo6–23 · 2,089 studies
Observational	13 mo5–33 · 395 studies	—	13 mo5–32 · 391 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out