Drug
Dexmedetomidine clinical trials
Also written Precedex, Dexdor and BXCL501.
- studies test it
- 1,435
- open now
- 288
- in phase 3
- 229
- first study started
- 2003
Keep track of what changes. Save the Dexmedetomidine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
1,433 studies that test it; most in 2024 (130); 1 more planned to start later
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2004 | 5 |
| 2005 | 8 |
| 2006 | 14 |
| 2007 | 13 |
| 2008 | 17 |
| 2009 | 27 |
| 2010 | 19 |
| 2011 | 34 |
| 2012 | 42 |
| 2013 | 36 |
| 2014 | 85 |
| 2015 | 63 |
| 2016 | 81 |
| 2017 | 95 |
| 2018 | 72 |
| 2019 | 87 |
| 2020 | 69 |
| 2021 | 97 |
| 2022 | 110 |
| 2023 | 109 |
| 2024 | 130 |
| 2025 | 113 |
| 2026 | 106 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 36
- Phase 1
- 84
- Phase 2
- 203
- Phase 3
- 229
- Phase 4
- 509
- No phase
- 480
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 45 · Other 1,390
Assiut University (99) · Ain Shams University (58) · Tanta University (49) · Peking University First Hospital (34) · Cairo University (34) · Yonsei University (34) · Zagazig University (19) · Seoul National University Hospital (18)
Often tested with
Tested in the same studies.
Ketamine (108) · Propofol (102) · Midazolam (81) · Lidocaine (58) · Fentanyl (50) · Dexamethasone (49) · Remifentanil (44) · Bupivacaine (42)
Studies
Open first, then newest update. How each study uses Dexmedetomidine is read from its arms, and is right about nine times in ten.
Testing it · 1,435
- The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil ConsumptionRecruitingNot applicableCiusss de L'Est de l'Île de MontréalNCT06684197Written as Dexmedetomidine
- Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery.RecruitingPhase 3Children's Cancer Hospital Egypt 57357NCT07878156Written as Dexmedetomidine 1mcg/kg
- Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear SurgeriesRecruitingPhase 2Minia UniversityNCT07878533Written as Dexmedetomidine
- Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department.Not yet recruitingPhase 4Sultan Qaboos UniversityNCT07874919Written as Dexmedetomidine
- Perioperative Multimodal Analgesia for Supratentorial CraniotomyRecruitingNot applicableBeijing Tiantan HospitalNCT07441421Written as Dexmedetomidine
- Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion BundleNot yet recruitingEarly Phase 1University of AlbertaNCT06824077Written as Dexmedetomidine
- Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After SurgeryNot yet recruitingPhase 4Peking University First HospitalNCT07576517Written as Dex-Esk
- Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After SurgeryNot yet recruitingPhase 4Peking University First HospitalNCT07576543Written as Dex-Esk
- Intravenous Dexmedetomidine as an Adjuvant to Locoregional Anesthesia in Pediatric SurgeryRecruitingPhase 2University Hospital, MontpellierNCT06736483Written as Dexmedetomidine
- REmifentanil And Dexmedetomidine for EarlY Intensive Blood Pressure Lowering in ICH.Not yet recruitingNot applicableThe Third Affiliated Hospital of Southern Medical UniversityNCT07695220Written as Remifentanil and Dexmedetomidine
- Opioid-Free Versus Opioid-Based Anesthesia in Thyroid SurgeryRecruitingNot applicableMalatya Egitim Ve Arastirma HastanesiNCT07864155Written as Dexmedetomidine and lidocaine
- Low Dose Dexmedetomidine as a Postoperative Pain AdjunctEnrolling by invitationPhase 2Nichole DoyleNCT06067893Written as Dexmedetomidine
- Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous NephrolithotomyNot yet recruitingPhase 4Assiut UniversityNCT07855068Written as Ketamine and Dexmedetomidine
- Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal AnesthesiaNot yet recruitingPhase 4Assiut UniversityNCT07855536Written as Dexmedetomidine
- Effect of Intravenous Versus Caudal Dexmedetomidine on Perfusion Index and Hemodynamic Responses in Children Undergoing Infraumbilical SurgeryNot yet recruitingPhase 4Assiut UniversityNCT07852039Written as Intravenous Dexmedetomidine
- Intranasal Dexmedetomidine for Severe Dental Anxiety: a Randomized TrialNot yet recruitingNot applicableSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT05500261Written as Dexmedetomidine
- Dexmedetomidine and Agitation After Nasal SurgeryRecruitingNot applicableFayoum University HospitalNCT06867302Written as Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)
- Safety and Efficacy of Dexamethasone Versus Dexmedetomidine as Adjuvants in PENG Block in Hip Surgeries for Postoperative Pain ManagementNot yet recruitingPhase 3Assiut UniversityNCT07847047Written as Dexmedetomidine
- Intranasal Dexmedetomidine and Perioperative Myocardial Injury in Patients Having Percutaneous Coronary InterventionsNot yet recruitingNot applicableSecond Affiliated Hospital, Zhejiang University, School of MedicineNCT07847580Written as Intranasal dexmedetomidine
- Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)RecruitingPhase 4Inonu UniversityNCT07824817Written as Dexmedetomidine
See all 1,435 studies that test Dexmedetomidine →
Given in every arm · 32 — Dexmedetomidine is usual care beside what is tested
- Intranasal Dexmedetomidine Combined With Esketamine for Emergence Quality After Suspension LaryngoscopyNot yet recruitingNot applicableThe First Hospital of Jilin UniversityNCT07880938Written as Dexmedetomidin
- Effects of taVNS Combined With Dexmedetomidine on POVNRecruitingNot applicableAffiliated Hospital of Nantong UniversityNCT07271147Written as Dexmedetomidine
- Intravenous Dexamethasone Added to Dexmedetomidine After Superior Trunk BlockNot yet recruitingPhase 4Gaziantep City HospitalNCT07795281Written as Intravenous Dexmedetomidine
- Opioid-Free Versus Opioid-Based Sedation for Endoscopic ProceduresNot yet recruitingNot applicableBakirkoy Dr. Sadi Konuk Research and Training HospitalNCT07649746Written as Dexmedetomidine
- Intravenous Dexamethasone as an Adjuvant to Dexmedetomidine After Superior Trunk Block for Arthroscopic Shoulder SurgeryNot yet recruitingNot applicableRecep KarakaşoğluNCT07525934Written as Dexmedetomidine
- Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) BlockRecruitingNot applicableUniversity Hospitals Cleveland Medical CenterNCT07174440Written as Dexmedetomidine
- Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative AnalgesiaNot yet recruitingPhase 3Zagazig UniversityNCT07330375Written as Dexmedetomidine
- Magnesium Sulfate Versus Lidocaine as Additives to Dexmedetomidine for Cough Suppression After Functional Endoscopic Sinus SurgeryNot yet recruitingPhase 3Assiut UniversityNCT07213037Written as Dexmedetomidine
- Intrathecal Morphine for Recovery and Outcomes After VATSCompletedNot applicableAtaturk UniversityNCT07231926Written as Dexmedetomidine
- Regional Block for Post-mastectomy AnalgesiaActive, not recruitingNot applicableZagazig UniversityNCT07683416Written as Dexmedetomidine Injection
- Closed Loop Acoustic Stimulation During Sedation With DexmedetomidineCompletedNot applicableWashington University School of MedicineNCT04206059Written as Dexmedetomidine
- The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain SurgeriesCompletedPhase 4Ain Shams UniversityNCT07475156Written as Dexmedetomidine (DEX)
- COMPARISON OF INTRAVENOUS DEXMEDETOMEDINE AND TRAMADOL FOR POST OPERATIVE SHIVERING AFTER SPINAL ANESTHESIA FOR CAESAREAN SECTIONCompletedPhase 4Liaquat National Hospital & Medical CollegeNCT07332572Written as Dexmedetomidine
- Ultrasound vs. Surgical ESP Block With Bupivacaine-Dexmedetomidine in Lumbar Fusion SurgeryCompletedPhase 4Fayoum University HospitalNCT06958718Written as Dexmedetomidine
- Role of Airway Topicalization in Awake Fiberoptic IntubationCompletedPhase 3Zagazig UniversityNCT06720220Written as Dexmedetomidine Hydrochloride
- Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver AblationCompletedNot applicablePeking University First HospitalNCT06003218Written as Dexmedetomidine-esketamine combination
- Continuous Nerve Block Block vs Combination of Single Block Plus Intravenous Lidocaine for Postoperative Pain.TerminatedPhase 4Jeremy KearnsNCT04208516Written as Dexmedetomidine
- Dexmedetomidine to Improve Outcomes During Emergence From Retroperitoneal Laparoscopic SurgeryCompletedNot applicableAir Force Military Medical University, ChinaNCT02316236Written as dexmedetomidine
- Comparison of Outcomes During MRI Sedation With Midazolam-dexmedetomidine Versus Ketamine-dexmedetomidineTerminatedNot applicableUniversity of LouisvilleNCT02129426Written as Dexmedetomidine
- Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid SurgeryStatus unknownNot applicableMahidol UniversityNCT04051099Written as Dexmedetomidine plus propofol infusion
Showing 20 of 32.
As the comparator · 43 — what is tested is compared with Dexmedetomidine
- Remimazolam Versus Dexmedetomidine for Sedation During NeuraxialNot yet recruitingPhase 4Icahn School of Medicine at Mount SinaiNCT07651956Written as Dexmedetomidine
- Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled TrialNot yet recruitingPhase 4The First Affiliated Hospital with Nanjing Medical UniversityNCT07377981Written as Dexmedetomidine
- The Impact of Dexmedetomidine Nasal Spray on Perioperative Anxiety in Neurosurgical PatientsNot yet recruitingNot applicableBeijing Tiantan HospitalNCT07801014Written as Dexmedetomidine
- The Use of Remimazolam Versus Dexmedetomidine for Patients Receiving Drug-Induced Sleep EndoscopyNot yet recruitingNot applicableFu Jen Catholic University HospitalNCT07459322Written as Dexmedetomidine
- Efficacy and Safety of Remimazolam Besylate for Sedation in Post-Non-Cardiac Surgery Patients Requiring Mechanical VentilationRecruitingPhase 4Beijing Shijitan Hospital, Capital Medical UniversityNCT06575530Written as Dexmedetomidine Hydrochloride
- Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.RecruitingPhase 4Instituto Mexicano del Seguro SocialNCT07073846Written as Intravenous Dexmedetomidine infusion + Standard Anesthesia
- Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.Not yet recruitingPhase 1/2Liaquat National Hospital & Medical CollegeNCT07180095Written as Intranasal dexmedetomidine
- Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean SectionRecruitingNot applicableTanta UniversityNCT07170267Written as Intrathecal dexmedetomidine
- Prevention of Emergence Agitation in Rhinoplasty With Subanesthetic Propofol and Single-Dose Dexmedetomidine: A Prospective Double-Blind Clinical StudyRecruitingNot applicableYuzuncu Yil UniversityNCT07144007Written as Dexmedetomidine
- Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve GastrectomyNot yet recruitingNot applicableIVO JURISICNCT07084753Written as Dexmedetomidin
- Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative SedationRecruitingNot applicableMaternal and Child Health Hospital of Hubei ProvinceNCT07050212Written as dexmedetomidine group
- Effects of Esketamine on Oxygenation and Quality of Recovery in Patients Undergoing Thoracoscopic SurgeryNot yet recruitingPhase 4Jinqiao QianNCT06822088Written as Dexmedetomidine
- Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated PatientsRecruitingPhase 4The First Affiliated Hospital with Nanjing Medical UniversityNCT05466708Written as Dexmedetomidine
- Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric SurgeryRecruitingNot applicableTanta UniversityNCT06125665Written as Dexmedetomidine
- The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal AnesthesiaNot yet recruitingNot applicablePusan National University Yangsan HospitalNCT05935657Written as Dexmedetomidine
- Comparative Effects of Remimazolam Tosylate and Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Thoracoscopic Surgery.CompletedNot applicableFirst Affiliated Hospital of Kunming Medical UniversityNCT07569614Written as Dexmedetomidine
- The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic SurgeryCompletedEarly Phase 1Affiliated Cancer Hospital & Institute of Guangzhou Medical UniversityNCT05242692Written as Dexmedetomidine
- Intravenous Magnesium Sulphate Versus Dexmedetomidine for Prevention of Emergence Agitation in Adult Otorhinolaryngologic SurgeryCompletedPhase 4Indonesia UniversityNCT07544173Written as Dexmedetomidine
- Dexmedetomidine Nasal Spray and Pediatric BronchoscopyCompletedNot applicableTongji HospitalNCT06755996Written as Dexmedetomidine injection
- Intranasal Remimazolam for Premedication in Pediatric PatientCompletedPhase 4Second Affiliated Hospital of Wenzhou Medical UniversityNCT04720963Written as Dexmedetomidine
Showing 20 of 43.
Codes
What other systems call Dexmedetomidine · ClinicalTrials.gg INT008783
- MeSH (NLM) D020927DexmedetomidineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 67VB76HONODEXMEDETOMIDINEConfirmed FDA, NLM, Wikidata
- RxNorm 48937Confirmed FDA, Wikidata
- Wikidata Q412133dexmedetomidineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47479DexmedetomidineOne source FDA
- DrugBank DB00633One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D020927 | Dexmedetomidine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 67VB76HONO | DEXMEDETOMIDINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 48937 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412133 | dexmedetomidine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47479 | Dexmedetomidine | One source FDA |
| DrugBank | DB00633 | — | One source Wikidata |
Also registered as dexmedetomidine hydrochloride (UNII 1018WH7F9I · RxNorm 228054).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.