An interventional study of Veress Needle Entry in Cholelithiasis, Postoperative Pain and Postoperative Nausea and Vomiting, sponsored by Islamabad Medical and Dental College. Completed at 1 site in Pakistan. Open to participants aged Up to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-09.
Sponsored by Islamabad Medical and Dental College · Not applicable, Interventional, and Treatment
This study will compare pain, nausea, and vomiting after keyhole gallbladder removal in adults with symptomatic gallstones.
The study will examine two commonly used methods for entering the abdomen. In the Veress needle method, a thin needle is used to introduce carbon dioxide gas before the first surgical port is inserted. In the direct trocar method, the first surgical port is inserted before the gas is introduced.
Adults aged 18-60 years undergoing planned keyhole gallbladder surgery at Akbar Niazi Teaching Hospital, Islamabad, Pakistan, will be invited to participate. The operating surgeon will choose the entry method according to routine clinical practice and the patient's clinical needs. The research team will record the method used without assigning treatment.
Pain will be assessed at 2, 6, and 24 hours after surgery using a scale from 0, meaning no pain, to 10, meaning the worst imaginable pain. Nausea and vomiting will be recorded during the first 24 hours. Additional pain relief and medicines used to treat nausea or vomiting will also be documented.
The findings may help clinicians understand whether postoperative symptoms differ between these two entry methods.
his single-centre, prospective comparative observational study will examine postoperative symptoms following Veress needle entry and direct trocar entry in adults undergoing elective laparoscopic cholecystectomy for symptomatic cholelithiasis.
Eligible patients will be recruited consecutively after informed consent. The abdominal entry technique will be selected by the operating surgeon according to routine practice and clinical judgment, independently of research participation. Participants will be classified into two cohorts according to the technique received.
The clinical protocol specifies standardized general anesthesia, postoperative analgesia, and prophylaxis against postoperative nausea and vomiting. Rescue analgesics and additional antiemetic treatment will be administered when clinically indicated and documented.
Baseline and perioperative information will be collected using a structured data collection form. Postoperative pain will be measured using a visual analogue scale at 2, 6, and 24 hours after surgery. The occurrence of nausea and vomiting will be recorded throughout the first 24 postoperative hours. Additional analgesic and antiemetic requirements will also be documented.
189 studies on the registry are indexed under Cholelithiasis; 42 are open to participants now.
This study's enrollment of 86 is close to the median of 90 across 135 interventional studies indexed under Cholelithiasis.
Browse Cholelithiasis studies →Islamabad Medical and Dental College is the lead sponsor of 15 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
nclusion Criteria:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients undergoing elective laparoscopic cholecystectomy using Veress needle entry. A Veress needle is used to establish carbon dioxide pneumoperitoneum before insertion of the primary trocar. The operating surgeon selects the technique according to routine clinical practice and clinical judgment, independently of study participation.
Procedure: Veress Needle Entry
Establishment of carbon dioxide pneumoperitoneum using a Veress needle before insertion of the primary trocar for laparoscopic cholecystectomy.
Postoperative pain score
Pain measured using a visual analogue scale from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain.
Time frame: at 2, 6 and 24 hours after surgery
Participants requiring rescue analgesia: within 24 hours after surgery.
Adults aged 18-60 years. Male or female patients with symptomatic cholelithiasis. Scheduled for elective laparoscopic cholecystectomy. Willing and able to provide informed consent.
Time frame: 3 months
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Islamabad Medical and Dental College