An interventional study of External oblique intercostal (EOI) block and Erector spinae plane block (ESPB) in Postoperative Pain, sponsored by Assiut University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-08-02.
Sponsored by Assiut University · Not applicable, Interventional, and Prevention
To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External oblique intercostal fascial plane block and Erector spinae plane block are effective in providing post-operative analgesia.
5,095 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's planned enrollment of 50 is below the median of 75 across 4,346 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Assiut University is the lead sponsor of 4,916 studies on the registry; 2,113 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Other: External oblique intercostal (EOI) block
Other: Erector spinae plane block (ESPB)
A high-frequency linear ultrasound probe will be placed in a longitudinal parasagittal orientation at the sixth intercostal space in the anterior midaxillary line. A 21G 10 cm needle will be inserted using an in plane approach. The tip of the needle will be placed into the fascial plane on the deep aspect of the external oblique muscle. A volume of 20 mL of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a mixture totaling 20 ml.) will be injected. The same procedure will be repeated for the opposite side.
A high-frequency linear ultrasound probe will be placed in a longitudinal parasagittal orientation 2.5-3 cm lateral to the T9 spinous process. The erector spinae muscles will be identified superficial to the tip of the T9 transverse process. A 21G 10 cm needle will be inserted using an in plane approach. The tip of the needle will be placed into the fascial plane on the deep aspect of the erector spinae muscle. The location of the needle tip will be confirmed by visible fluid spread lifting the erector spinae muscle off the bony shadow of the transverse process on ultrasonographic imaging. A volume of 20 mL of Local Anesthetic mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a mixture totaling 20 ml.) will be injected. The same procedure will be repeated for the opposite side.
Nalbuphine consumption in mg equivalent to morphine dose.
mg
Time frame: 24 hours postoperatively
Numerical Rating Scale (NRS) at rest and when coughing
11-point scale where 0=no pain and 10=worst pain
Time frame: at 1, 2,4 , 8, 16 and 24 hours postoperatively
Analgesic drug consumption other than nalbuphine
in mg
Time frame: 24 hours postoperatively
Heart Rate
beats /min
Time frame: Intraoperatively at 0, 5,10, 20, and 30 minutes. Then every 15 min thereafter till the end of surgery
Mean Arterial Pressure
mmHg
Time frame: Intraoperatively at 0, 5,10, 20, and 30 minutes. Then every 15 min thereafter till the end of surgery
Incidence of Postoperative nausea & vomiting (PONV)
Number of patients developing PONV
Time frame: 24 hours postoperatively
Shoulder pain
Number of patients developing Shoulder pain
Time frame: 24 hours postoperatively
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Assiut University