Drug
Morphine clinical trials
Also written Duramorph and DepoDur.
Includes 8 studies of Morphine hydrochloride.
- studies test it
- 398
- open now
- 44
- in phase 3
- 56
- first study started
- 1994
Keep track of what changes. Save the Morphine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
396 studies that test it; most in 2016 (30)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1995 | 2 |
| 1997 | 1 |
| 1998 | 1 |
| 2001 | 3 |
| 2002 | 2 |
| 2003 | 3 |
| 2004 | 5 |
| 2005 | 10 |
| 2006 | 16 |
| 2007 | 14 |
| 2008 | 23 |
| 2009 | 14 |
| 2010 | 18 |
| 2011 | 19 |
| 2012 | 16 |
| 2013 | 15 |
| 2014 | 21 |
| 2015 | 27 |
| 2016 | 30 |
| 2017 | 17 |
| 2018 | 21 |
| 2019 | 11 |
| 2020 | 18 |
| 2021 | 10 |
| 2022 | 17 |
| 2023 | 14 |
| 2024 | 15 |
| 2025 | 20 |
| 2026 | 12 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 35
- Phase 2
- 65
- Phase 3
- 56
- Phase 4
- 139
- No phase
- 125
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 29 · Other 369
Assiut University (21) · Mahidol University (8) · Actavis Inc. (6) · Cairo University (5) · Cukurova University (5) · Ataturk University (4) · Ain Shams University (4) · Tanta University (4)
Often tested with
Tested in the same studies.
Bupivacaine (27) · Fentanyl (19) · Acetaminophen (15) · Dexmedetomidine (14) · Ketamine (13) · Methadone (12) · Ropivacaine (12) · Hydromorphone (11)
Studies
Open first, then newest update. How each study uses Morphine is read from its arms, and is right about nine times in ten.
Testing it · 398
- A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic CoughNot yet recruitingPhase 4McMaster UniversityNCT07288528Written as Morphine Sulphate
- ITM vs ITM+Clonidine for Lumbar FusionsNot yet recruitingPhase 3MaineHealthNCT07846657Written as Intrathecal Morphine + Intrathecal Clonidine
- How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play?RecruitingNot applicableSara L. KrollNCT07778511Written as Morphine
- Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive CrisisNot yet recruitingPhase 4Assistance Publique - Hôpitaux de ParisNCT07826988Written as Group 03 : Paracetamol + Morphine + Nefopam
- Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean SectionRecruitingPhase 4Anne Juul WikkelsøNCT06797973Written as Intrathecal Morphine
- PENG Block Versus Intrathecal Morphine for Early Postoperative Recovery After Total Hip ArthroplastyNot yet recruitingNot applicableErzincan Binali Yildirim UniversitesiNCT07803133Written as Intrathecal Morphine
- Ultrasound-Guided Posterior Quadratus Lumborum Block With Bupivacaine and Dexmedetomidine Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean DeliveryNot yet recruitingPhase 4Assiut UniversityNCT07807592Written as Intrathecal Morphine
- Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation SurgeriesRecruitingNot applicableTanta UniversityNCT07777627Written as Intrathecal Morphine
- Efficacy of Adding Intrathecal Morphine to Erector Spinae Plane Block for Postoperative Analgesia After Midline LaparotomyRecruitingNot applicableSohag UniversityNCT07720739Written as Intrathecal Morphine
- Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative PainNot yet recruitingPhase 2National University of La RiojaNCT07657468Written as Omega-3 fatty acids + Morphine group
- Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic SurgeryRecruitingPhase 4Northwestern UniversityNCT05351229Written as Morphine Sulfate
- Intrathecal Analgesia in Laparoscopic Nissen Fundoplication.Enrolling by invitationNot applicableKarlstad Central HospitalNCT07629323Written as Intrathecal Morphine 100ug
- Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control TrialRecruitingNot applicableAnqing Municipal HospitalNCT06990893Written as Morphine
- Determining the Optimal Dose of Intrathecal Morphine for Post-Cesarean AnalgesiaRecruitingNot applicableUniversity of IoanninaNCT07023497Written as Intrathecal morphine
- Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIaRecruitingPhase 1/2University Hospital, GrenobleNCT04427826Written as Morphine hydrochloride
- Intraosseous Morphine Administration During Anterior Cruciate Ligament ReconstructionRecruitingPhase 4The Methodist Hospital Research InstituteNCT06511232Written as Intraosseous Morphine
- Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal EpiduralRecruitingNot applicableSamuel Lunenfeld Research Institute, Mount Sinai HospitalNCT06572241Written as Intrathecal morphine
- Spinal Anesthesia For Enhanced Recovery After Liver SurgeryRecruitingNot applicableUniversity of ManitobaNCT03715517Written as Morphine
- Intrathecal Versus Epidural Morphine for Post-Cesarean AnalgesiaRecruitingPhase 4Hospital Central do FunchalNCT07386353Written as Intrathecal Morphine
- Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean SectionNot yet recruitingPhase 4Istituto Giannina GasliniNCT07377630Written as Intrathecal Morphine
See all 398 studies that test Morphine →
Given in every arm · 121 — Morphine is usual care beside what is tested
- SPIP vs ESP Block in Cardiac SurgeryNot yet recruitingNot applicableOndokuz Mayıs UniversityNCT07780773Written as morphine PCA
- Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine SurgeriesRecruitingNot applicableZagazig UniversityNCT07883616Written as Morphine
- Efficacy and Safety of Intravenous Lidocaine Versus Placebo in Patients Receiving Morphine-rachi AnalgesiaNot yet recruitingPhase 3GCS Ramsay Santé pour l'Enseignement et la RechercheNCT07076641Written as MORPHINE
- Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac SurgeryRecruitingNot applicableOndokuz Mayıs UniversityNCT07164677Written as IV morphine patient-controlled analgesia
- Post-Op Pain Control for Prophylactic Intramedullary Nailing.RecruitingPhase 3St. Louis UniversityNCT03823534Written as Morphine
- Intraoperative Placement of Vancomycin-impregnated Calcium Sulfate Beads Conjugated With Analgesics to Improve Spine Surgery OutcomesNot yet recruitingPhase 2Ganesh M. ShankarNCT07201987Written as Morphine (local, via calcium sulfate beads)
- PRO-RSTAP: Effect of TAP and RS Blocks on Recovery After Inguinal Hernia Surgery (PRO-RSTAP)RecruitingNot applicableTampere University HospitalNCT07423910Written as Morphine
- Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic ResectionRecruitingPhase 4University of California, San DiegoNCT04849455Written as Spinal Morphine
- Comparison Between 2 Techniques for Lumbar-ESPBCompletedNot applicablePapa Giovanni XXIII HospitalNCT07104097Written as Morphine
- Multimodal Pain Study in Free Flap PatientsCompletedPhase 4University of Kansas Medical CenterNCT04246697Written as Morphine
- Evaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic ProcessesCompletedNot applicableIuliu Hatieganu University of Medicine and PharmacyNCT07207304Written as Morphine (+)
- Combined Pericapsular Nerve Group Block and Lateral Femoral Cutaneous Nerve Block for Pediatric Hip SurgeriesCompletedPhase 2Kasr El Aini HospitalNCT06417268Written as Morphine
- Symptom-inhibited Fentanyl InductionCompletedPhase 4Pouya AzarNCT05905367Written as Slow-release oral morphine
- Levorphanol as a Second Line Opioid in Reducing Pain in Patients With CancerTerminatedEarly Phase 1M.D. Anderson Cancer CenterNCT03579446Written as Morphine
- Bilateral Erector Spinae Plane Block for Postoperative Chronic Pain After Open Heart SurgeryCompletedNot applicableOndokuz Mayıs UniversityNCT06315959Written as morphine PCA
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using ParticipantsCompletedPhase 1Astellas Pharma Global Development, Inc.NCT04448561Written as morphine
- A Study to Assess the Effect of AZD4041 on Respiratory Drive in Recreational Opioid Users.CompletedPhase 1AstraZenecaNCT05587998Written as Morphine
- Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.WithdrawnPhase 4University of MiamiNCT06114121Written as Duramorph
- Comparison of Two Analgesic Strategies After Scheduled CaesareanCompletedPhase 4GCS Ramsay Santé pour l'Enseignement et la RechercheNCT04755712Written as Morphine
- NOL-Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane BlockCompletedNot applicableInstitutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. IliescuNCT06070701Written as Morphine
Showing 20 of 121.
As the comparator · 195 — what is tested is compared with Morphine
- Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic SurgeryRecruitingPhase 4Peking University First HospitalNCT07525986Written as Morphine
- Morphine or Ketamine for AnalgesiaRecruitingPhase 3Columbia UniversityNCT06835504Written as Morphine sulphate
- BUprenorphine Versus Morphine for Postcesarean Analgesia (BUMP)RecruitingPhase 4Icahn School of Medicine at Mount SinaiNCT07786012Written as morphine
- Tegileridine for Postoperative Pain After Adolescent Scoliosis SurgeryRecruitingPhase 4Peking Union Medical College HospitalNCT07229495Written as morphine
- Subcutaneous Methadone for Cesarean Analgesia: a Non Inferiority Study Using QoR-10Not yet recruitingNot applicableClinica Alemana de SantiagoNCT07777029Written as morphine
- Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal SurgeryRecruitingPhase 4Xiangya Hospital of Central South UniversityNCT07412223Written as Morphine
- Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs OxycodoneRecruitingPhase 4Murdoch Childrens Research InstituteNCT06186141Written as Morphine
- Phase II Clinical Study of the Efficacy and Safety of HSK55718 in the Treatment of Abdominal Postoperative PainRecruitingPhase 2Yingyong Zhou,MD,PhDNCT07491146Written as Morphine
- Transversalis Fascia Plane Block Versus Low-Dose Intrathecal Morphine for Open Inguinal Hernia RepairRecruitingNot applicableHitit UniversityNCT07695935Written as Intrathecal morphine
- Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open NephrectomyRecruitingNot applicableCairo UniversityNCT07642193Written as Intravenous morphine
- Evaluation of the Efficacy of Sublingual Sufentanil (Prescribed as Rescue Analgesia for Acute Postoperative Pain) on the Quality of Health Recovery After Surgery: a Randomized, Controlled, Multicenter, Open-label Trial Against an Active Comparator (SUBLIME)Not yet recruitingPhase 4University Hospital, Strasbourg, FranceNCT07624006Written as Morphine sulfate (10 mg every 4 hours as needed)
- A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal SurgeryRecruitingPhase 2Haisco Pharmaceutical Group Co., Ltd.NCT07533786Written as morphine
- Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip ArthroplastyNot yet recruitingNot applicablePoznan University of Medical SciencesNCT07584200Written as Intrathecal Morphine
- A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Orthopedic SurgeryNot yet recruitingPhase 2Haisco Pharmaceutical Group Co., Ltd.NCT07551739Written as morphine
- Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral MorphineRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT06464146Written as Morphine
- Comparative Analysis of Analgesic Approaches in the Early Period After CABGRecruitingNot applicablePrimorsky Regional General Hospital #1NCT07451522Written as Morphine (+)
- Use of the Methoxyflurane as Pain-killer in the Prehospital Management of Acute Myocardial InfarctionNot yet recruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT07445737Written as Morphine
- Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal MorphineRecruitingPhase 3University of TorontoNCT07050277Written as Intrathecal Morphine
- Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal SurgeryRecruitingEarly Phase 1University of VirginiaNCT06387303Written as Morphine
- Dexmedetomidine Versus Morphine During Cooling Therapy in NeonatesNot yet recruitingPhase 2Ipsita GoswamiNCT06985290Written as Morphine Infusion
Showing 20 of 195.
Codes
What other systems call Morphine · ClinicalTrials.gg INT007853
- MeSH (NLM) D009020MorphineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 76I7G6D29CMORPHINEConfirmed FDA, NLM, Wikidata
- RxNorm 7052Confirmed FDA, Wikidata
- Wikidata Q81225morphineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62051MorphineOne source FDA
- DrugBank DB00295One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009020 | Morphine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 76I7G6D29C | MORPHINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7052 | — | Confirmed FDA, Wikidata |
| Wikidata | Q81225 | morphine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62051 | Morphine | One source FDA |
| DrugBank | DB00295 | — | One source Wikidata |
Also registered as morphine sulfate (UNII X3P646A2J0 · RxNorm 30236).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.