Drug
Acetaminophen clinical trials
Also written Paracetamol, Tylenol and Ofirmev.
- studies test it
- 653
- open now
- 58
- in phase 3
- 112
- first study started
- 1994
Keep track of what changes. Save the Acetaminophen studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
642 studies that test it; most in 2018 (48)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1997 | 2 |
| 1998 | 1 |
| 1999 | 1 |
| 2000 | 3 |
| 2002 | 4 |
| 2003 | 4 |
| 2004 | 4 |
| 2005 | 9 |
| 2006 | 17 |
| 2007 | 22 |
| 2008 | 15 |
| 2009 | 19 |
| 2010 | 21 |
| 2011 | 24 |
| 2012 | 32 |
| 2013 | 40 |
| 2014 | 35 |
| 2015 | 46 |
| 2016 | 40 |
| 2017 | 45 |
| 2018 | 48 |
| 2019 | 48 |
| 2020 | 24 |
| 2021 | 31 |
| 2022 | 18 |
| 2023 | 23 |
| 2024 | 21 |
| 2025 | 20 |
| 2026 | 24 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 13
- Phase 1
- 72
- Phase 2
- 102
- Phase 3
- 112
- Phase 4
- 265
- No phase
- 121
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 129 · Other 524
GlaxoSmithKline (20) · Pamukkale University (13) · Montefiore Medical Center (11) · Mallinckrodt (11) · University Hospital, Clermont-Ferrand (9) · Johnson & Johnson Consumer and Personal Products Worldwide (9) · Janssen Korea, Ltd., Korea (7) · University of Monastir (7)
Often tested with
Tested in the same studies.
Ibuprofen (108) · Tramadol (29) · Ketorolac (26) · Gabapentin (22) · Oxycodone (19) · Celecoxib (18) · Hydrocodone (16) · Morphine (15)
Studies
Open first, then newest update. How each study uses Acetaminophen is read from its arms, and is right about nine times in ten.
Testing it · 653
- Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New InjuriesEnrolling by invitationPhase 4State University of New York at BuffaloNCT07393503Written as Acetaminophen 500Mg Tab
- Enhanced Recovery After Surgery (ERAS) in Live Donor Kidney Transplant RecipientsEnrolling by invitationPhase 4Baylor Research InstituteNCT06997016Written as Acetaminophen
- A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT05319730Written as Acetaminophen (or equivalent)
- Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingPhase 4Northwestern UniversityNCT07840183Written as Acetaminophen
- Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean SectionNot yet recruitingPhase 4Assiut UniversityNCT07855588Written as Paracetamol
- Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic SurgeriesNot yet recruitingPhase 4Assiut UniversityNCT07855575Written as Paracetamol 2 g
- Intravenous Metoclopramide Versus Intravenous Acetaminophen for Acute Concussion TreatmentNot yet recruitingPhase 4Montefiore Medical CenterNCT07634393Written as Acetaminophen
- Comparing Pain Improvement for Intravenous Versus Oral Acetaminophen in Acute Pelvic PainNot yet recruitingPhase 4Montefiore Medical CenterNCT07595302Written as Acetaminophen 1000mg PO
- Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive CrisisNot yet recruitingPhase 4Assistance Publique - Hôpitaux de ParisNCT07826988Written as Group 03 : Paracetamol + Morphine + Nefopam
- Co-administration of Acetaminophen With Ibuprofen to Improve Duct-Related Outcomes in Extremely Premature InfantsRecruitingPhase 2Mount Sinai Hospital, CanadaNCT05340582Written as Acetaminophen Injection
- Impact of Preemptive Analgesia on Postoperative Pain in Orthognathic SurgeryRecruitingPhase 4University of Puerto RicoNCT07571252Written as Acetaminophen
- Quadro-Iliac Plane Block for Pain Control After Posterior Spinal Instrumentation SurgeryNot yet recruitingEarly Phase 1Istanbul Medipol University HospitalNCT07711522Written as Paracetamol (acetaminophen)
- Acetaminophen vs Placebo for Postoperative Analgesia After Abdominal SurgeryNot yet recruitingPhase 4Konya City HospitalNCT07720791Written as Acetaminophen
- A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantRecruitingPhase 1Novo Nordisk A/SNCT07710729Written as Acetaminophen
- High- vs Standard-Dose Intravenous Magnesium for Acute HeadacheRecruitingNot applicableUniversity of MonastirNCT07779486Written as Paracetamol 1 g
- Pain Control During ESWL Using Non-Opioid AnalgesicsNot yet recruitingPhase 4University of GaziantepNCT07512297Written as Paracetamol (drug)
- Optimizing Pain Treatment in Children On Mechanical VentilationRecruitingPhase 3Weill Medical College of Cornell UniversityNCT06994442Written as Acetaminophen
- Opiranserin for Minimally Invasive CholecystectomyRecruitingNot applicableGangnam Severance HospitalNCT07620665Written as Opiranserin+Acetaminophen
- A Study of Intravenous Acetaminophen for Small Bowel ObstructionEnrolling by invitationPhase 4Mayo ClinicNCT05878015Written as Acetaminophen
- Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF PatientsNot yet recruitingPhase 4Western Galilee Hospital-NahariyaNCT07536425Written as Paracetamol / Acetaminophen
See all 653 studies that test Acetaminophen →
Given in every arm · 276 — Acetaminophen is usual care beside what is tested
- Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids TrialRecruitingPhase 4University of MichiganNCT06671002Written as Acetaminophen
- Comparison of Two Postoperative Care Strategies After Breast SurgeryRecruitingNot applicableMoumtzidou Maria AikateriniNCT07880223Written as Paracetamol
- A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)RecruitingPhase 2/3Merck Sharp & Dohme LLCNCT07570173Written as Acetaminophen
- A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010)RecruitingPhase 2Merck Sharp & Dohme LLCNCT07785609Written as Acetaminophen (or equivalent)
- Preoperative Celecoxib and Acetaminophen Versus Acetaminophen Alone for Pain Control After Pediatric AdenotonsillectomyNot yet recruitingPhase 1/2NYU Langone HealthNCT07870447Written as Acetaminophen
- A Clinical Trial of MK-6255 to Treat Endometrial and Ovarian Cancer (MK-6255-001)Not yet recruitingPhase 1Merck Sharp & Dohme LLCNCT07870278Written as Acetaminophen
- A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06824467Written as Acetaminophen (or equivalent)
- Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill QuantityEnrolling by invitationPhase 4AdventHealthNCT07750639Written as Acetaminophen
- A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)Not yet recruitingPhase 2Merck Sharp & Dohme LLCNCT07709000Written as Acetaminophen (or similar antipyretic)
- TAP vs. ESP Blocks for Post-Cesarean AnalgesiaNot yet recruitingNot applicableMaternity Hospital - State Budgetary Institution of the Rostov Region, TaganrogNCT07853482Written as Ketoprofen and Paracetamol
- A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric ParticipantsRecruitingPhase 2Hoffmann-La RocheNCT05039619Written as Acetaminophen/paracetamol
- Nephrostomy Tract Infiltration for Pain Control After PCNLRecruitingNot applicableHitit UniversityNCT07721571Written as Intravenous Tramadol and Paracetamol
- Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic SurgeriesRecruitingPhase 4Northwell HealthNCT06379425Written as Acetaminophen
- A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body WeightNot yet recruitingPhase 1Novo Nordisk A/SNCT07845578Written as Paracetamol
- Post-Vasectomy Pain StudyRecruitingPhase 1Columbia UniversityNCT07824258Written as Acetaminophen
- A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or ObesityRecruitingPhase 1Eli Lilly and CompanyNCT07803744Written as Acetaminophen
- Suzetrigine in Tonsillectomy for Opioid-sparing Pain ManagementNot yet recruitingPhase 4Stanford UniversityNCT07821931Written as Acetaminophen
- A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular LymphomaRecruitingPhase 2M.D. Anderson Cancer CenterNCT06043323Written as Acetaminophen
- Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) TrialRecruitingPhase 4University of MichiganNCT05722002Written as Acetaminophen
- A Study of Eloralintide (LY3841136) in Participants With Obesity or OverweightRecruitingPhase 1Eli Lilly and CompanyNCT07738614Written as Acetaminophen
Showing 20 of 276.
As the comparator · 110 — what is tested is compared with Acetaminophen
- Post-op Analgesia of Nail Unit ProceduresNot yet recruitingPhase 4University of MiamiNCT07820969Written as Acetaminophen
- Suzetrigine Versus Standard Analgesia After Skin Cancer SurgeryNot yet recruitingPhase 4University of MinnesotaNCT07843134Written as Acetaminophen Plus Ibuprofen
- A Clinical Trial of GRT7040 in Adults With Acute Pain Following BunionectomyNot yet recruitingPhase 2Grünenthal GmbHNCT07807644Written as Hydrocodone bitartrate/ acetaminophen (HB/APAP)
- Holistic Healing for Knee OsteoarthritisNot yet recruitingNot applicableAll India Institute of Medical Sciences, JodhpurNCT07768709Written as Paracetamol
- Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal TreatmentRecruitingEarly Phase 1Dow University of Health SciencesNCT07759349Written as Acetaminophen
- Effect of Nonsteroidal Anti-Inflammatory Drug Restriction on the Efficacy of Platelet-Rich Plasma in Knee OsteoarthritisNot yet recruitingNot applicableFederal University of São PauloNCT07766330Written as Acetaminophen
- Comparison Between the Effectiveness of Low-Grade Laser Therapy vs. Conventional Analgesics for Pain Reduction During Orthodontic Treatment in Malay Female PopulationRecruitingNot applicableROA RAAD FADHELNCT07747350Written as Conventional Analgesic (Paracetamol)
- Suzetrigine Frame Trial Comparing Suzetrigine and AcetaminophenRecruitingPhase 3Wake Forest University Health SciencesNCT07525219Written as acetaminophen
- A Phase IV Randomized Trial of Maxigesic® Versus Standard Analgesia After Radical GastrectomyNot yet recruitingPhase 4Yonsei UniversityNCT07687394Written as Acetaminophen (Newaminophen Premix)
- A Study of Combogesic® 325 in Adolescent Patients With Moderate to Severe Postoperative Pain Associated With Orthopedic SurgeryNot yet recruitingPhase 3AFT Pharmaceuticals, Ltd.NCT07225140Written as Acetaminophen 500mg
- Dexamethasone Plus Metoclopramide Versus Paracetamol/NSAIDs for Primary HeadacheNot yet recruitingPhase 4Pak Emirates Military HospitalNCT07605065Written as Paracetamol/NSAIDs
- Suzetrigine vs Norco-postoperative Mohs PainEnrolling by invitationPhase 4Baylor Research InstituteNCT07575230Written as Norco 5Mg-325Mg Tablet
- Meloxicam in Mohs Micrographic SurgeryRecruitingPhase 4University of OklahomaNCT07200544Written as Acetaminophen 500mg
- RCT: Suzetrigine vs Norco for Post-op PainNot yet recruitingPhase 4Jacob LensingNCT07195669Written as Norco
- A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic PainNot yet recruitingPhase 1University of BaghdadNCT06812936Written as Acetaminophen
- Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular FunctionRecruitingPhase 4University of ZurichNCT03781544Written as Paracetamol
- A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy VolunteersRecruitingNot applicableSinew Pharma Inc.NCT05563961Written as Panadol®
- Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus SurgeryRecruitingNot applicableCairo UniversityNCT06293586Written as Paracetamol
- Effects of Perioperative Intravenous Dexamethasone in Clinical Outcomes After Total Knee Arthroplasty in a Hispanic PopulationNot yet recruitingPhase 4University of Puerto RicoNCT06042426Written as Oxycodone and acetaminophen
- Comparison Between Pregabalin and Acetaminophen for the Treatment of Post-Mastectomy Pain SyndromeCompletedPhase 4Subas AliNCT07567924Written as Acetaminophen
Showing 20 of 110.
Codes
What other systems call Acetaminophen · ClinicalTrials.gg INT006846
- MeSH (NLM) D000082AcetaminophenConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 362O9ITL9DACETAMINOPHENConfirmed FDA, NLM
- RxNorm 161One source FDA
- NCI Thesaurus C198AcetaminophenOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000082 | Acetaminophen | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 362O9ITL9D | ACETAMINOPHEN | Confirmed FDA, NLM |
| RxNorm | 161 | — | One source FDA |
| NCI Thesaurus | C198 | Acetaminophen | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.