Local anesthetics clinical trials
A class of medicines: the studies that test any of its 20 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones. In MeSH: Anesthetics, Local.
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Medicines in this class
Studies that test each. A study of two counts under both, and once above.
- Lidocaine, Prilocaine Drug Combination
- 42
- Dyclonine
- 1
- Pramoxine
- 1
- Oxethazaine
- 1
Studies by the year they started
3,123 studies that test it; most in 2019 (228); 7 more planned to start later
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 3 |
| 2001 | 1 |
| 2002 | 7 |
| 2003 | 13 |
| 2004 | 16 |
| 2005 | 31 |
| 2006 | 22 |
| 2007 | 56 |
| 2008 | 83 |
| 2009 | 73 |
| 2010 | 83 |
| 2011 | 100 |
| 2012 | 108 |
| 2013 | 123 |
| 2014 | 168 |
| 2015 | 197 |
| 2016 | 212 |
| 2017 | 177 |
| 2018 | 198 |
| 2019 | 228 |
| 2020 | 156 |
| 2021 | 187 |
| 2022 | 154 |
| 2023 | 192 |
| 2024 | 214 |
| 2025 | 176 |
| 2026 | 142 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 221 · Other 2,921
Assiut University (84) · Cairo University (60) · Pacira Pharmaceuticals, Inc (53) · Ain Shams University (49) · Mayo Clinic (37) · Duke University (26) · Tanta University (25) · Northwestern University (24)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing one of them · 3,142
- Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Sphenopalatine Ganglion Block for Functional Endoscopic Sinus SurgeryNot yet recruitingPhase 4Sohag UniversityNCT07911202Written as Dexmedetomidine & Bupivacaine.
- The Role of Janus Kinase (JAK) and Voltage-gated Sodium Channels (Nav) on Pain and ItchRecruitingNot applicableAalborg UniversityNCT07203274Written as lidocaine cream
- SPARK Study - Sympathetic Periarterial Radial Block in Healthy VolunteersNot yet recruitingPhase 4Duke UniversityNCT07429292Written as Lidocaine 2%
- Prospective RCT Lidocaine & Levobupivacaine on Block Dynamics After Subparaneural Popliteal Sciatic Nerve BlockRecruitingPhase 4Chinese University of Hong KongNCT04397484Written as 0.5% Levobupivacaine
- Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk BlockRecruitingNot applicableChinese University of Hong KongNCT04941664Written as 0.5% levobupivacaine
- PENG With LFCB vs. ESP Blocks for Pediatric Hip SurgeryRecruitingPhase 4Poznan University of Medical SciencesNCT07023094Written as Ropivacaine 0.2% for PENG Block
- SIRI Levels Following PENG Block in Pediatric Hip SurgeryRecruitingNot applicablePoznan University of Medical SciencesNCT07607535Written as Ropivacaine 0.2% Injectable Solution
- REctus Sheath TrialRecruitingPhase 2Duke UniversityNCT07068243Written as 1.0% lidocaine with epinephrine (1:100,000)
- Lidocaine Infiltration and Neuroimmunomodulation in Head and Neck Cancer SurgeryRecruitingPhase 4University Medical Centre LjubljanaNCT07922759Written as Lidocaine HCl 1%
- Comparing Long-Acting Local Pain Relief Methods in PLIF SurgeryNot yet recruitingNot applicableFirst Affiliated Hospital of Kunming Medical UniversityNCT07919275Written as Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Lumbar Paravertebral Block vs Erector Spinae Plane Block in Elderly Patients Undergoing Lumbar Spine SurgeryRecruitingNot applicablePoznan University of Medical SciencesNCT07607509Written as Ropivacaine 0.2% Injectable Solution
- PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip ArthroplastyRecruitingPhase 4Poznan University of Medical SciencesNCT07180979Written as Ropivacaine 0.5% Injectable Solution
- SII Levels Following iPACK Block With Adductor Canal Block in Knee ArthroplastyRecruitingNot applicablePoznan University of Medical SciencesNCT07449442Written as Ropivacaine Hydrocloride
- Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid HemorrhageRecruitingPhase 2The University of Texas Medical Branch, GalvestonNCT07294118Written as Lidocaine
- Role of Perineural Catheter in Pain Control and Opioid Consumption After Major Amputation of Lower LimbNot yet recruitingPhase 4Aga Khan UniversityNCT07896798Written as Bubpivacaine
- The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac SurgeryRecruitingPhase 4Vanderbilt University Medical CenterNCT07224711Written as Lidocaine HCl 0.8% in D5W
- Split Face Study of the Duration of Local Anesthetics - Fifth ArmNot yet recruitingPhase 4Weill Medical College of Cornell UniversityNCT07724418Written as Lidocaine HCl/Epinephrine
- Two Bupivacaine Concentrations for Recto-Intercostal Fascial Plane Block After Laparoscopic CholecystectomyNot yet recruitingNot applicableMedipol UniversityNCT07841951Written as Bupivacaine 0.25% - recto-intercostal fascial plane block
- INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib FracturesRecruitingPhase 4Zachary WarrinerNCT05642026Written as Ropivacaine
- Interpectoral-pectoserratus Plane Block for Minimally Invasive Aortic Valve Replacement Via Right Anterior MinithoracotomyRecruitingPhase 4Algemeen Ziekenhuis Maria MiddelaresNCT06369870Written as Levobupivacaine Hydrochloride 0.25 % Injectable Solution
See all 3,142 studies that test one of the local anesthetics →
Codes
What other systems call Local anesthetics · ClinicalTrials.gg INT006979
- MeSH (NLM) D000779Anesthetics, LocalOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000779 | Anesthetics, Local | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.