Drug
Liposomal Bupivacaine clinical trials
A product of Bupivacaine; its studies count on that page too.
- studies test it
- 296
- open now
- 49
- in phase 3
- 49
- first study started
- 2011
Keep track of what changes. Save the Liposomal Bupivacaine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- Exparel
- 181
Development codes
Studies by the year they started
294 studies that test it; most in 2019 (39); 1 more planned to start later
| Year | Studies |
|---|---|
| 2011 | 2 |
| 2012 | 10 |
| 2013 | 13 |
| 2014 | 29 |
| 2015 | 24 |
| 2016 | 20 |
| 2017 | 18 |
| 2018 | 27 |
| 2019 | 39 |
| 2020 | 17 |
| 2021 | 23 |
| 2022 | 13 |
| 2023 | 11 |
| 2024 | 21 |
| 2025 | 8 |
| 2026 | 19 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 7
- Phase 1
- 18
- Phase 2
- 31
- Phase 3
- 49
- Phase 4
- 165
- No phase
- 36
What it is tested for
Each study’s main condition, where its own words name it.
- Pain
- 3
Who runs them
Industry 37 · Other 259
Pacira Pharmaceuticals, Inc (34) · Mayo Clinic (11) · University of Minnesota (9) · Wake Forest University Health Sciences (9) · Beijing Tiantan Hospital (6) · St. Luke's Hospital, Pennsylvania (4) · The Cleveland Clinic (4) · Indiana University (4)
Often tested with
Tested in the same studies.
Ropivacaine (10) · Dexamethasone (6) · Epinephrine (5) · Hydromorphone (2) · Methylprednisolone (2) · Fentanyl (1) · Therapeutic Procedure (1) · Complementary or Alternative Medical Procedure (1)
Studies
Open first, then newest update. How each study uses Liposomal Bupivacaine is read from its arms, and is right about nine times in ten.
Testing it · 296
- Pain Control for Undergoing Costal Cartilage HarvestingRecruitingPhase 4Mayo ClinicNCT05285566Written as Exparel
- Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody FusionEnrolling by invitationPhase 2/3Foundation for Orthopaedic Research and EducationNCT06350981Written as Exparel
- A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting SurgeryNot yet recruitingPhase 4Mayo ClinicNCT07570940Written as Liposomal bupivacaine
- Effect of Liposomal Bupivacaine on Rebound Pain After Peripheral Nerve Block in Orthopedic Surgery.Not yet recruitingPhase 4Shanghai Jiao Tong University Affiliated Sixth People's HospitalNCT07606911Written as liposomal bupivacaine
- Liposomal Bupivacaine vs Ropivacaine for Post-hemorrhoidectomy AnalgesiaNot yet recruitingPhase 4Tongliao City People's HospitalNCT07795203Written as Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee ArthroplastyNot yet recruitingPhase 4Wake Forest University Health SciencesNCT07097493Written as Liposomal Bupivacaine
- Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty AnalgesiaRecruitingPhase 2Washington University School of MedicineNCT07689162Written as Liposomal Bupivacaine
- Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip SurgeryNot yet recruitingPhase 4Peking University First HospitalNCT07643792Written as Liposomal bupivacaine (LB)
- Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal BupivacaineRecruitingNot applicableZhejiang UniversityNCT07263295Written as Liposomal Bupivacaine 10mL
- The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic SurgeryRecruitingNot applicableBeijing Tiantan HospitalNCT07432711Written as Liposomal bupivacaine plus bupivacaine
- R.E.C.K vs Exparel in Robotic NephrectomyRecruitingPhase 3Wake Forest University Health SciencesNCT07092566Written as Exparel
- Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve GastrectomyRecruitingEarly Phase 1Texas Tech University Health Sciences CenterNCT06349772Written as Exparel
- The Effect of Liposomal Bupivacaine Erector Spinae Plane BlockNot yet recruitingNot applicableSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT07667439Written as Liposomal bupivacaine plus bupivacaine hydrochloride
- Effect of Liposomal Bupivacaine TAPB Combined With Oxycodone PCIA on Postoperative Gastrointestinal Recovery in Patients Undergoing Major Abdominal SurgeryRecruitingNot applicableTianjin First Central HospitalNCT07651722Written as Liposomal bupivacaine (LB)
- Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and AnalgesiaEnrolling by invitationNot applicableNanjing First Hospital, Nanjing Medical UniversityNCT07587203Written as Liposomal bupivacaine
- Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After ThoracoscopyRecruitingPhase 4Milton S. Hershey Medical CenterNCT03737292Written as Exparel
- Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered (IPSA) Block vs. Local Infiltration Analgesia in Knee Replacement SurgeryEnrolling by invitationPhase 4Cedars-Sinai Medical CenterNCT07584915Written as Bupivacaine liposome injectable suspension (IPSA block)
- Bupivacaine Liposome Suspension Administration to Decreasre Peri-procedural Pain in Interventional Radiology (IR) ProceduresNot yet recruitingPhase 4Massachusetts General HospitalNCT07535411Written as Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Efficacy of Liposomal Bupivacaine Post SeptorhinoplastyEnrolling by invitationPhase 3Jessyka LighthallNCT05964868Written as Liposomal Bupivacaine
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic OncologyRecruitingNot applicableBeijing Tiantan HospitalNCT07458295Written as Liposomal bupivacaine plus bupivacaine
See all 296 studies that test Liposomal Bupivacaine →
Given in every arm · 12 — Liposomal Bupivacaine is usual care beside what is tested
- Exparel and DexamethasoneNot yet recruitingPhase 4Duke UniversityNCT07614802Written as Liposomal Bupivacaine with Bupivacaine
- Exparel v Dexamethasone in RCREnrolling by invitationPhase 4Rothman Institute OrthopaedicsNCT06575010Written as Liposomal bupivacaine
- Exparel vs Block for ACL ReconstructionEnrolling by invitationPhase 4Rothman Institute OrthopaedicsNCT06006624Written as Exparel 30 mL
- Liposomal Bupivacaine With Dexamethasone for Foot SurgeryEnrolling by invitationPhase 4Rothman Institute OrthopaedicsNCT06465992Written as Exparel 266 MG Per 20 ML Injection
- Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)Active, not recruitingPhase 2M.D. Anderson Cancer CenterNCT04189783Written as Liposomal Bupivacaine
- ESP Block for Post Cesarean AnalgesiaCompletedPhase 4Duke UniversityNCT05664958Written as bupivacaine liposome injectable suspension
- Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological MalignanciesCompletedPhase 4Mayo ClinicNCT04258631Written as Liposomal Bupivacaine
- Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a Pectoral Plane Block in Women Undergoing Breast AugmentationCompletedPhase 1Pacira Pharmaceuticals, IncNCT04293809Written as Exparel Injectable Product
- Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline IncisionStatus unknownPhase 4Danbury HospitalNCT03870685Written as Exparel
- 0.25% Bupivacaine Versus a Mixture of 0.25% Bupivacaine and 1.3 % Liposomal Bupivacaine in Patients Undergoing TkaTerminatedPhase 3Montefiore Medical CenterNCT03303794Written as Exparel
- Liposomal Bupivacaine in Total Knee ArthroplastyCompletedNot applicableBronx-Lebanon Hospital Center Health Care SystemNCT03541265Written as Exparel
- Exparel vs Exparel Plus ACB in TKAsWithdrawnPhase 4The Hawkins FoundationNCT02365727Written as Liposomal bupivacaine
As the comparator · 10 — what is tested is compared with Liposomal Bupivacaine
- Post Operative Infusion Pump Pain StudyRecruitingPhase 4Rutgers, The State University of New JerseyNCT07349810Written as 1.3% liposomal bupivacaine (Exparel)
- Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for MastectomiesRecruitingPhase 4United States Naval Medical Center, PortsmouthNCT06252662Written as Liposomal bupivacaine
- A Study of TLC590 for Postsurgical Pain Following BunionectomyActive, not recruitingPhase 3TLC Biopharmaceuticals, Inc.NCT07222748Written as Liposomal Bupivacaine
- Continuous vs Liposomal Bupivacaine Interscalene Block for Proximal Humeral Fracture (CLIP)CompletedPhase 4The University of Hong KongNCT04928664Written as Liposomal bupivacaine
- Liposomal Bupivacaine With Standard Bupivacaine Versus Dexmedetomidine With Standard BupivacaineCompletedPhase 3The University of Hong KongNCT06235606Written as Bupivacaine Liposome 13.3 Milligrams/Milliliter [Exparel]
- Transverse Abdominus Plane Block StudyWithdrawnPhase 2University of Colorado, DenverNCT05216055Written as Liposomal bupivacaine
- Four Quadrants Transverse Abdominus Plane (4Q-TAP) Block With Plain and Liposomal Bupivacaine vs. Thoracic Epidermal Analgesia (TEA) in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) on an Enhanced Recovery PathwayCompletedPhase 3M.D. Anderson Cancer CenterNCT03359811Written as Liposomal Bupivacaine
- Open-Label CA-008 (Vocacapsaicin) in BunionectomyCompletedPhase 2Concentric AnalgesicsNCT03885596Written as Exparel
- Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of HYR-PB21 in Healthy VolunteersCompletedPhase 1Fruithy Medical Pty LtdNCT04169256Written as Liposomal bupivacaine
- Efficacy of Interscalene Brachial Plexus Block With Liposomal Bupivacaine for Arthroscopic Shoulder SurgeryCompletedPhase 4St. Luke's-Roosevelt Hospital CenterNCT01977352Written as Liposomal bupivacaine