ClinicalTrials.gg
Sign In

Heart Failure clinical trials

The registry lists 6,331 studies for Heart Failure across more than 10 countries. 1,396 are recruiting or about to start. 4,742 of them are mainly about Heart Failure (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Heart Failure, Systolic: 6,604 studies, 1,454 open.

ClinicalTrials.gov finds 7,932 studies for Heart Failure. How that becomes 6,327 here

This page counts the studies the registry files under Heart Failure, and those it files under no condition that list Heart Failurethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 7,932Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −270Filed under a narrower condition, counted on its own pageHeart Failure, Diastolic 112 · Heart Failure, Systolic 99 · Cardio-Renal Syndrome 52
  3. −465List Heart Failure as a condition, but the registry did not file them under itMost often written as “Chronic Heart Failure” (123), “Heart Failure With Preserved Ejection Fraction” (65), and “Heart Failure With Reduced Ejection Fraction” (50). The registry filed them under other conditions only, most often Atrial Fibrillation (33) and Pulmonary Disease, Chronic Obstructive (29).
  4. −870Match it another way266 name it in the title, 62 in a keyword, and 542 by a synonym or other text the search reads.
  5. 6,327The count on this page728 of them list Heart Failure in their own words; the registry filed them under no condition.

Get an email when these change. Save the Heart Failure studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies
See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
3,144
Recruiting
968
Status unknown
805
Terminated
450
Not yet recruiting
343
Active, not recruiting
266

Phase

Phase 2
657
Phase 3
483
Phase 4
470
Phase 1
330
Early Phase 1
40

Where

United States
2,156
Germany
600
United Kingdom
482
Canada
452
Italy
449
France
448

Who runs them

Abbott Medical Devices (111) · Medtronic Cardiac Rhythm and Heart Failure (108) · Mayo Clinic (69) · Novartis Pharmaceuticals (64) · Duke University (64) · AstraZeneca (61) · Boston Scientific Corporation (51) · National Heart, Lung, and Blood Institute (NHLBI) (48)

What is being tested here

Drugs under test in Heart Failure studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Finerenone13819
Dapagliflozin101344
Empagliflozin91139
Valsartan7629
Vericiguat7215
Sacubitril valsartan5834
Furosemide5731
Sacubitril5620
Sotagliflozin447
Colchicine437

Drug classes tested here SGLT2 inhibitors 26 open · Mineralocorticoid receptor antagonists (MRAs) 16 open · Diuretics 12 open · Angiotensin receptor blockers (ARBs) 12 open · Beta blockers 9 open

Coming up

85phase 3 studies under way
442studies finish main data collection within a year20 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 968 Heart Failure studies recruiting now, 691 (71%) set no upper age limit and 89 (9%) stop at 75 or younger. 64 (7%) take children under 18. 12 (1%) are for women only and 4 (<1%) for men only; 96 (10%) take healthy volunteers.

Recruiting studies that take each age, of 968
AgeWomenMen
1047 (5%)49 (5%)
18768 (79%)762 (79%)
30839 (87%)832 (86%)
40877 (91%)870 (90%)
50896 (93%)889 (92%)
65935 (97%)925 (96%)
75909 (94%)900 (93%)
85804 (83%)795 (82%)

Across all 6,331 studies, recruiting or not: 10% stop at 75 or younger and 4% at 65; 7% take children; 1% are for women only and 1% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Heart Failure studies take

Of 184 phase 2 interventional studies under Heart Failure, half reached primary completion within 29 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 114 mo4–36 · 130 studies7 mo2–16 · 76 studies36 mo17–58 · 54 studies
Phase 1/239 mo27–48 · 43 studies——
Phase 229 mo17–47 · 184 studies20 mo14–31 · 73 studies39 mo21–66 · 111 studies
Phase 2/333 mo16–54 · 24 studies——
Phase 339 mo25–57 · 151 studies36 mo20–44 · 63 studies50 mo28–63 · 88 studies
Phase 431 mo22–56 · 183 studies—32 mo22–56 · 164 studies
Interventional, no phase31 mo16–52 · 1,354 studies34 mo18–62 · 236 studies29 mo16–50 · 1,118 studies
Observational41 mo23–89 · 975 studies34 mo20–57 · 182 studies45 mo23–99 · 793 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting27

Show 22 more

Results posted4

Stopped1

Newly registered32

Show 27 more

Studies

Recruiting first, then most recently updated. Showing 50 of 6,331. Browse all 6,331 → or search them.