Drug

Sacubitril valsartan clinical trials

Includes 88 studies of Sacubitril valsartan sodium hydrate.

studies test it: 91
open now: 7
in phase 3: 24
first study started: 2007

Keep track of what changes. Save the sacubitril valsartan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

Watch these studies

How studies write it

Studies that test it under each name

Name

SACUBITRIL - VALSARTAN (formerly LCZ696, ENTRESTO®): 2

Combined with it in one product

Roxadustat;Sacubitril Valsartan Sodium Tablets;: 1
Entresto®: 1

Studies by the year they started

91 studies that test it; most in 2016 (13)

Studies that test sacubitril valsartan, by start year
Year	Studies
2007	1
2009	4
2010	2
2011	2
2012	10
2013	4
2014	3
2015	2
2016	13
2017	4
2018	7
2019	10
2020	9
2021	7
2022	5
2023	2
2024	3
2025	2
2026	1

By phase

A phase 1/2 study counts in both.

Early Phase 1: 1
Phase 1: 4
Phase 2: 30
Phase 3: 24
Phase 4: 30
No phase: 7

What it is tested for

Each study’s main condition, where its own words name it.

Heart Failure: 37
Hypertension: 13
Essential Hypertension: 7
Diabetes Mellitus, Type 2: 2
Myocardial Infarction: 2
Prediabetic State: 1
Acquired Immunodeficiency Syndrome: 1
Cardiomyopathy, Hypertrophic: 1
COVID-19: 1
Erectile Dysfunction: 1
Hypertension, Pulmonary: 1
Sleep Apnea Syndromes: 1

Who runs them

Industry 41 · Other 50

Novartis Pharmaceuticals (41) · Vanderbilt University Medical Center (3) · Brigham and Women's Hospital (2) · Mayo Clinic (2) · Duke University (2) · The Cleveland Clinic (2) · Ohio State University (1) · Saga University (1)

Often tested with

Tested in the same studies.

Valsartan (9) · Enalapril (3) · Sitagliptin (3) · Icatibant (2) · P-Aminohippuric Acid (2) · Sacubitril (2) · Aprepitant (1) · Sertraline (1)

Studies

Open first, then newest update. How each study uses sacubitril valsartan is read from its arms, and is right about nine times in ten.

Testing it · 91

See all 91 studies that test sacubitril valsartan →

Given in every arm · 7 — sacubitril valsartan is usual care beside what is tested

As the comparator · 4 — what is tested is compared with sacubitril valsartan

Codes

What other systems call sacubitril valsartan · ClinicalTrials.gg INT015221

UNII (FDA) 688RNR55GHSACUBITRIL VALSARTANOne source FDA
NCI Thesaurus C222078Sacubitril ValsartanOne source FDA

System	Code	Name there	Checked by
UNII (FDA)	688RNR55GH	SACUBITRIL VALSARTAN	One source FDA
NCI Thesaurus	C222078	Sacubitril Valsartan	One source FDA

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.