Drug class
Diuretics clinical trials
A class of medicines: the studies that test any of its 20 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the diuretics studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Bendroflumethiazide
- 2
- Cicletanine
- 2
- Efonidipine
- 1
- Azosemide
- 1
Studies by the year they started
795 studies that test it; most in 2016 (43); 2 more planned to start later
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1995 | 1 |
| 1997 | 2 |
| 1998 | 2 |
| 1999 | 4 |
| 2000 | 6 |
| 2001 | 5 |
| 2002 | 7 |
| 2003 | 13 |
| 2004 | 23 |
| 2005 | 33 |
| 2006 | 34 |
| 2007 | 30 |
| 2008 | 26 |
| 2009 | 36 |
| 2010 | 39 |
| 2011 | 29 |
| 2012 | 33 |
| 2013 | 39 |
| 2014 | 40 |
| 2015 | 39 |
| 2016 | 43 |
| 2017 | 40 |
| 2018 | 40 |
| 2019 | 27 |
| 2020 | 26 |
| 2021 | 31 |
| 2022 | 27 |
| 2023 | 33 |
| 2024 | 35 |
| 2025 | 20 |
| 2026 | 31 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
- Hypertension
- 153
Who runs them
Industry 188 · Other 620
Novartis (36) · University of Zurich (27) · Boehringer Ingelheim (23) · Assistance Publique - Hôpitaux de Paris (10) · Brigham and Women's Hospital (9) · Takeda (9) · Yale University (8) · University of California, San Diego (8)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 808
- Optimal Diuretic Therapies for Acute Heart Failure With Volume OverloadRecruitingPhase 3Johannes GrandNCT06166654Written as Acetazolamide
- Spironolactone in Alcohol Use Disorder (SAUD)RecruitingPhase 1National Institute on Drug Abuse (NIDA)NCT05807139Written as Spironolactone
- DECONGEST-AHF: Vasodilatation or Loop Diuretics in Acute Heart FailureRecruitingPhase 4Copenhagen University Hospital, RigshospitaletNCT05276219Written as Furosemide Injection
- A Phase IV, Two-part, Open-label Study Assessing the Pharmacokinetics, Safety and Pharmacodynamics of Spironolactone Oral Suspension in Pediatric PatientsNot yet recruitingPhase 4CMP Development, LLCNCT06021860Written as Spironolactone Oral Suspension
- Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of PregnancyRecruitingPhase 2Massachusetts General HospitalNCT07238400Written as Chlorthalidone 25 mg daily
- Spironolactone for Pulmonary Arterial HypertensionRecruitingPhase 2National Institutes of Health Clinical Center (CC)NCT01712620Written as Spironolactone
- SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive TherapyNot yet recruitingPhase 4Ottawa Hospital Research InstituteNCT07687160Written as Spironolactone (drug)
- DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.RecruitingPhase 2Incannex Healthcare LtdNCT07635563Written as IHL-42X: 2.5 mg dronabinol + 125 mg acetazolamide
- Preoperative AcetazolamideRecruitingPhase 4Prisma Health-UpstateNCT07101250Written as Acetazolamide 500 MG Extended Release Oral Capsule
- Role of Postpartum Furosemide in Recovery of Patients With Severe PreeclampsiaRecruitingNot applicableLady Reading Hospital, PakistanNCT07861685Written as Furosemide and Potassium
- The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased Donor Renal TransplantationRecruitingNot applicableLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sNCT07726134Written as Furosemide
- Regression in Left Ventricular Hypertrophy and Fibrosis in Aortic StenosisNot yet recruitingPhase 2University College, LondonNCT07539259Written as Spironolactone (drug)
- Mechanisms of Diuretic Resistance in Heart Failure, Aim 2RecruitingPhase 1Yale UniversityNCT05753059Written as Amiloride
- HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of LifeRecruitingPhase 3University Medical Center GroningenNCT05373264Written as Hydrochlorothiazide 25 mg
- Sleep Apnea in ElderlyRecruitingPhase 4VA Office of Research and DevelopmentNCT02703220Written as Acetazolamide
- ACetazolamide in Patients With Heart Failure, to Decrease Weight and relIEVE Symptoms.Not yet recruitingPhase 3University Hospital, MontpellierNCT07737964Written as Acetazolamide
- Evaluating the Use of Oral Indapamide to Reduce Disabiltiy Progression in Progressive Multiple Sclerosis (MS)Not yet recruitingPhase 2Eva M.M. StrijbisNCT07765212Written as Indapamide
- CaOx Stone PreventionRecruitingPhase 4Icahn School of Medicine at Mount SinaiNCT07225764Written as Chlorthalidone
- Efficacy and Safety of Spironolactone in Pediatric Hemodialysis Patients With Anemia.Not yet recruitingPhase 2Ain Shams UniversityNCT07715318Written as Spironolactone (drug)
- Effect of a Furosemide Stress Test-Guided Strategy on Liberation From Continuous Renal Replacement Therapy in Critically Ill Patients With Acute Kidney InjuryRecruitingPhase 4Chiang Mai UniversityNCT06229990Written as Furosemide Injection
Codes
What other systems call Diuretics · ClinicalTrials.gg INT007387
- MeSH (NLM) D004232DiureticsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004232 | Diuretics | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.