Abbott: Heart Failure trials

The registry lists 106 Heart Failure studies with Abbott as lead sponsor. 5 are open to participants now and 43 have results posted.

Early Phase 1 1Phase 1 1Phase 2 3Phase 3 5Phase 4 4No phase 93(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Merlin Expanded ECG NSRNot yet recruitingNCT07877805
• Left Bundle Branch Area Pacing (LBBAP) PMCF StudyRecruitingNCT07217392Not applicable
• CardioMEMS HF System Coverage With Evidence Development StudyRecruitingNCT06779552
• Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureRecruitingNCT06526195Not applicable
• Acute Response to Left Bundle Branch Area Pacing With SyncAVRecruitingNCT06436053
• Hong Kong and Taiwan HM3 PMSTerminatedNCT04703855Not applicableResults posted
• The ARIES HeartMate 3 Pump IDE StudyCompletedNCT04069156Not applicableResults posted
• Hemodynamic-GUIDEd Management of Heart FailureCompletedNCT03387813Not applicableResults posted
• Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™CompletedNCT03247829Results posted
• HeartMate 3 CE Mark Study Long Term Follow-upCompletedNCT03022461Results posted
• CardioMEMS HF System OUS Post Market StudyCompletedNCT02954341Results posted
• MOMENTUM 3 Continued Access ProtocolCompletedNCT02892955Not applicableResults posted
• Prevention of Non-Surgical Bleeding by Management of HeartMate II Patients Without Antiplatelet TherapyCompletedNCT02836652Phase 4Results posted
• MultiPoint Pacing™ Post Market StudyCompletedNCT02832622Results posted
• CardioMEMS European Monitoring Study for Heart FailureCompletedNCT02693691Not applicableResults posted
• Quartet 1457Q Left Ventricular (LV) Lead Investigational Device Exemption (IDE) StudyCompletedNCT02548455Not applicableResults posted
• Quartet Lead and Resynchronization Therapy Options III (QUARTO_III)CompletedNCT02476201Not applicableResults posted
• Post-market Study of Multi-Vector Left Ventricular Lead Performance in Chinese Patients With Chronic Heart FailureCompletedNCT02367716Results posted
• HF Assessment With BNP in the Home: Part IITerminatedNCT02351063Not applicableResults posted
• CardioMEMS HF System Post Approval StudyCompletedNCT02279888Results posted
• Optisure Lead Post Approval StudyTerminatedNCT02235545Results posted
• MOMENTUM 3 IDE Clinical Study ProtocolCompletedNCT02224755Not applicableResults posted
• HeartMate 3™ CE Mark Clinical Investigation PlanCompletedNCT02170363Not applicableResults posted
• MOre REsponse on Cardiac Resynchronization Therapy With MultiPoint PacingTerminatedNCT02006069Not applicableResults posted
• Advance Cardiac Resynchronization Therapy (CRT) RegistryCompletedNCT01805154Results posted
• MultiPoint Pacing IDE StudyCompletedNCT01786993Phase 3Results posted
• QUARTO-II Study to Evaluate the Management of Patients Resynchronized With the QuartetTM LV Quadripolar LeadCompletedNCT01733368Results posted
• Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CASActive, not recruitingNCT01626079Not applicableResults posted
• CentriMag RVAS U.S. Post-approval Study ProtocolCompletedNCT01568424Not applicableResults posted
• More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT ChallengesCompletedNCT01510652Not applicableResults posted
• Clinical Benefits in Optimized Remote HF Patient ManagementCompletedNCT01482598Not applicableResults posted
• Quartet Lead and Resynchronization Therapy OptionsCompletedNCT01295840Phase 4Results posted
• Acute Kidney Injury Neutrophil Gelatinase-Associated Lipocalin Evaluation of Symptomatic Heart Failure StudyCompletedNCT01291836Results posted
• Real Time 3-Dimensional Echocardiography for Left Ventricular Lead Site Selection to Reduce Cardiac Resynchronization Therapy Non-Responder RatesCompletedNCT01278030Not applicableResults posted
• QuickFlex Micro Left Ventricular Lead Post Approval StudyCompletedNCT01179477Results posted
• QuickOpt Chronic StudyCompletedNCT01172067Not applicableResults posted
• Promote Q Cardiac Resynchronization Therapy Defibrillator (CRT-D) and Quartet Left Ventricular Heart Lead StudyCompletedNCT00990665Not applicableResults posted
• SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibrillator PatientsCompletedNCT00940888Results posted
• BOOST - Benefit of Frequent Optimization After Cardiac Resynchronization Therapy Device ReplacementTerminatedNCT00929474Not applicableResults posted
• Detect Fluid Early From Intra-thoracic Impedance MonitoringCompletedNCT00916929Not applicableResults posted
• CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary BypassCompletedNCT00819793Not applicableResults posted
• Safety and Efficacy Study of the QuickFlex Micro Model 1258T Left Heart Pacing LeadCompletedNCT00763698Not applicableResults posted
• Safety and Efficacy of Automatic Testing Feature in New ICDs and CRT-DsCompletedNCT00746356Not applicableResults posted
• Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS)CompletedNCT00547729Not applicableResults posted
• CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure PatientsCompletedNCT00531661Not applicableResults posted
• Response of Cardiac Resynchronization Therapy Optimization With Ventricle to Ventricle Timing in Heart Failure PatientsCompletedNCT00187200Phase 4Results posted
• Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination TherapyCompletedNCT00121485Not applicableResults posted
• Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac TransplantationCompletedNCT00121472Not applicableResults posted
• ASCEND CSP IDE StudyActive, not recruitingNCT06830746Not applicable
• Validation of CardioMEMS HF System Cardiac Output Algorithm IDECompletedNCT05428384
• Septal Mapping And Resynchronisation Therapy- (SMART) StudyCompletedNCT04595305Not applicable
• Implantation of the HeartMate 3 in Subjects With Heart Failure Using Surgical SWIFT HM3 PMSCompletedNCT04548128
• CentriMag Failure-to-Wean Post Approval StudyCompletedNCT04464785
• SyncAV Post-Market TrialActive, not recruitingNCT04100148Not applicable
• MOMENTUM 3 Pivotal Cohort Extended Follow-up PASCompletedNCT03982979
• Mapping and Pacing of the His Bundle for Heart Failure Patients With Left Bundle Branch BlockCompletedNCT03803995Not applicable
• Study Protocol/ Registry of MultiPoint™ Pacing in BrazilTerminatedNCT03001141
• The Application of Negative Atrioventricular Hysteresis in Cardiac Resynchronization TherapyCompletedNCT02903940
• Device-based QRS EvaluationCompletedNCT02814214
• The Application of Negative Atrioventricular Hysteresis in Cardiac Resynchronization Therapy With MultiPoint PacingCompletedNCT02782598
• MultiPoint Pacing Mapping StudyTerminatedNCT02547207
• MultiPoint Pacing Programming Guided by Noninvasive HemodynamicsCompletedNCT02064751Not applicable
• Evaluation of Left Ventricular (LV) Lead Positioning Using MediGuideCompletedNCT01917266
• MPP Programming StudyCompletedNCT01856725Not applicable
• Trial of Autonomic neuroModulation for trEatment of Chronic Heart FailureWithdrawnNCT01820130Not applicable
• A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral RegurgitationTerminatedNCT01772108Not applicable
• Screening for Advanced Heart Failure Treatment (SEE-HF)CompletedNCT01626404
• EnSite NavX-Guided Coronary Sinus Mapping During CRT ImplantCompletedNCT01615835Not applicable
• Characterization of Cardiac Hemodynamics During MultiSite PacingCompletedNCT01564186
• Dependence of LV Hemodynamics on Pacing SiteCompletedNCT01564173
• Quadripolar Pacing Post Approval StudyCompletedNCT01555619
• Clinical Evaluation of Mediguide System in Cardiac Resynchronization Therapy (CRT) ImplantsCompletedNCT01519739Not applicable
• Selected Site Pacing to Avoid Phrenic Nerve Stimulation in Cardiac Resynchronization Patients With Quadripolar Left Ventricular LeadsCompletedNCT01484613
• Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device (LVAD) and Medical ManagementCompletedNCT01452802
• Spinal Cord Stimulation For Heart FailureCompletedNCT01362725Phase 2/3
• Heart Failure (HF) Outpatient Monitoring Evaluation (HOME) StudyCompletedNCT01347567Not applicable
• Effectiveness and Reliability of VectSelect™ Feature for Avoidance of Phrenic Nerve Stimulation in Cardiac Resynchronisation Therapy (CRT) PatientsCompletedNCT01244308
• INvestigation on Routine Follow-up in CONgestive HearT FAilure Patients With Remotely Monitored Implanted Cardioverter Defibrillators (ICD) SysTemsCompletedNCT01200381Not applicable
• CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass for Pediatric PatientsWithdrawnNCT01171950Not applicable
• Wireless, Intermittent Monitoring of Right Heart Pressures in HFCompletedNCT01162707Not applicable
• Left Atrial Pressure Monitoring to Optimize Heart Failure TherapyCompletedNCT01121107Not applicable
• Risk Stratification and Benefits With Cardiac Resynchronization Therapy (CRT)CompletedNCT00996086
• BeneMACS Study:HeartMate 2 (HM2)Left Ventricular Assist Device (LVAD) Survival in Non Transplant Patients is Equal/Better Than Results in Medical LiteratureCompletedNCT00983190Not applicable
• Multisite Pacing With a Quadripolar LeadCompletedNCT00964938Phase 4
• QuickOptTM Study - Using the QuickOptTM Method for Timing Cycle OptimizationCompletedNCT00918294Not applicable
• Investigation of Transvenous Versus Epicardial Left Ventricular Stimulation TechniqueCompletedNCT00819117Not applicable
• Data Collection Study of Wedge Pressure Data in Patients With CRT-D DevicesCompletedNCT00811551
• TRI-V Heart Failure (HF) Implanted Cardioverter Defibrillator (ICD) StudyCompletedNCT00746135Not applicable
• Safety and Efficacy Study to Evaluate the Effect of SLV320 on Renal Function in Patients With Worsening Heart FailureTerminatedNCT00744341Phase 2
• Atrial Fibrillation Management in Congestive Heart Failure With AblationCompletedNCT00652522Not applicable
• EnSite Real-Time Cardiac Performance Measurements (RT CPM) StudyCompletedNCT00632450
• Cardiac Resynchronization Therapy (CRT) Based Heart Failure Monitoring StudyCompletedNCT00632372
• Placement of CS/LV Pacing Leads With EnSite NavX GuidanceWithdrawnNCT00577187Early Phase 1
• Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal FunctionTerminatedNCT00568009
• AVJ Ablation Followed by Resynchronization Therapy in Patients With CHF and AFTerminatedNCT00547794
• Cardiac Resynchronization Therapy Defibrillator Based Impedance Monitoring StudyCompletedNCT00500838Not applicable
• A Study of Ularitide in the Treatment of Subjects With Acute Decompensated Heart FailureWithdrawnNCT00487799Phase 1
• RISK Stratification Using a Combination of Cardiac Troponin T and Brain Natriuretic Peptide in Patients Receiving CRT-DCompletedNCT00453622
• Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support: a Multicentre, Parallel-Group, Randomised, Double-Blind, Double-Dummy Study of Levosimendan Versus Dobutamine in Patients With Acute Heart Failure.CompletedNCT00348504Phase 3
• Trip HF Study: Triple Resynchronization in Paced Heeart Failure PatientsCompletedNCT00187265Not applicable