Drug
Sotagliflozin clinical trials
Also written SAR439954, LX4211 and INPEFA.
- studies test it
- 60
- open now
- 9
- in phase 3
- 19
- first study started
- 2009
Keep track of what changes. Save the sotagliflozin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Combined with it in one product
Studies by the year they started
60 studies that test it; most in 2017 (13)
| Year | Studies |
|---|---|
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 3 |
| 2012 | 1 |
| 2013 | 5 |
| 2014 | 1 |
| 2015 | 9 |
| 2016 | 3 |
| 2017 | 13 |
| 2018 | 7 |
| 2019 | 3 |
| 2022 | 1 |
| 2024 | 5 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 25
- Phase 2
- 13
- Phase 3
- 19
- Phase 4
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 48 · Other 12
Lexicon Pharmaceuticals (34) · Sanofi (14) · Icahn School of Medicine at Mount Sinai (2) · Steno Diabetes Center Copenhagen (2) · University of California, San Diego (1) · Juan Badimon (1) · Baylor Research Institute (1) · Oregon Health and Science University (1)
Often tested with
Tested in the same studies.
Finerenone (3) · Empagliflozin (2) · Ramipril (2) · Canagliflozin (2) · Semaglutide (2) · Hydrochlorothiazide (1) · Midazolam (1) · Metoprolol (1)
Studies
Open first, then newest update. How each study uses sotagliflozin is read from its arms, and is right about nine times in ten.
Testing it · 60
- Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)Enrolling by invitationPhase 4Baylor Research InstituteNCT07547878Written as Sotagliflozin
- Precision T1D Platform - New Therapies for Cardio-Renal ComplicationsNot yet recruitingPhase 2Oregon Health and Science UniversityNCT07594145Written as Sotagliflozin
- Sotagliflozin as Prevention of Anthracycline-Related CardiotoxicityNot yet recruitingPhase 2Icahn School of Medicine at Mount SinaiNCT07572175Written as Sotagliflozin
- Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 DiabetesRecruitingPhase 2University of DundeeNCT06435156Written as Sotagliflozin
- Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney DiseaseRecruitingPhase 3Alessandro DoriaNCT06217302Written as Sotagliflozin
- Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 InhibitorsNot yet recruitingPhase 2AdventHealth Translational Research InstituteNCT07421518Written as SGLT-2 inhibitor (Sotagliflozin)
- Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic CardiomyopathyRecruitingEarly Phase 1University of PennsylvaniaNCT06433050Written as Sotagliflozin
- Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxiaNot yet recruitingPhase 2Steno Diabetes Center CopenhagenNCT06147232Written as Sotagliflozin
- Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 DiabetesRecruitingPhase 3Steno Diabetes Center CopenhagenNCT06082063Written as Sotagliflozin
- A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic CardiomyopathyActive, not recruitingPhase 3Lexicon PharmaceuticalsNCT06481891Written as Sotagliflozin
- Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) PatientsCompletedPhase 4Juan BadimonNCT05562063Written as Sotagliflozin
- Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 DiabetesActive, not recruitingPhase 1/2University of California, San DiegoNCT05696366Written as Sotagliflozin
- Antithrombotic Activities of Sotagliflozin vs. EmpagliflozinCompletedPhase 4Icahn School of Medicine at Mount SinaiNCT06618976Written as Sotagliflozin
- Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular RiskTerminatedPhase 3Lexicon PharmaceuticalsNCT03315143Written as Sotagliflozin
- Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)TerminatedPhase 3Lexicon PharmaceuticalsNCT03521934Written as Sotagliflozin
- A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted ConditionsCompletedPhase 1SanofiNCT03776227Written as sotagliflozin (SAR439954)
- Effect of Rifampicin on the Pharmacokinetics and Pharmacodynamics of SotagliflozinCompletedPhase 1SanofiNCT03063580Written as Sotagliflozin (SAR439954)
- A Study to Evaluate the Effect of Food on the Pharmacokinetics of Sotagliflozin and to Explore the Relative Bioavailability in Healthy SubjectsCompletedPhase 1SanofiNCT03174548Written as Sotagliflozin (SAR439954)
- A Drug to Drug Interaction Study of Sotagliflozin With HydrochlorothiazideCompletedPhase 1SanofiNCT03387657Written as Sotagliflozin (SAR439954)
- Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate HypertensionCompletedPhase 2SanofiNCT03462069Written as Sotagliflozin (SAR439954)
Codes
What other systems call sotagliflozin · ClinicalTrials.gg INT006154
- MeSH (NLM) C575681sotagliflozinConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 6B4ZBS263YSOTAGLIFLOZINConfirmed FDA, NLM, Wikidata
- Wikidata Q27088840sotagliflozinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C119623SotagliflozinOne source FDA
- DrugBank DB12713One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C575681 | sotagliflozin | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 6B4ZBS263Y | SOTAGLIFLOZIN | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27088840 | sotagliflozin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C119623 | Sotagliflozin | One source FDA |
| DrugBank | DB12713 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.