Drug class
Mineralocorticoid Receptor Antagonists clinical trials
A class of medicines: the studies that test any of its 5 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the mineralocorticoid receptor antagonists studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Canrenone
- 2
Studies by the year they started
305 studies that test it; most in 2013 (27); 4 more planned to start later
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2002 | 2 |
| 2003 | 7 |
| 2004 | 11 |
| 2005 | 9 |
| 2006 | 12 |
| 2007 | 17 |
| 2008 | 13 |
| 2009 | 11 |
| 2010 | 18 |
| 2011 | 11 |
| 2012 | 11 |
| 2013 | 27 |
| 2014 | 19 |
| 2015 | 14 |
| 2016 | 14 |
| 2017 | 11 |
| 2018 | 11 |
| 2019 | 9 |
| 2020 | 10 |
| 2021 | 8 |
| 2022 | 17 |
| 2023 | 14 |
| 2024 | 10 |
| 2025 | 6 |
| 2026 | 12 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 46 · Other 266
Brigham and Women's Hospital (16) · Massachusetts General Hospital (7) · Estetra (6) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (6) · Bayer (6) · Vanderbilt University (5) · Central Hospital, Nancy, France (4) · University of Virginia (4)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 312
- Reducing Arterial Inflammation Using Eplerenone and Statins in HIVNot yet recruitingPhase 2/3Massachusetts General HospitalNCT07892664Written as Eplerenone
- Spironolactone in Alcohol Use Disorder (SAUD)RecruitingPhase 1National Institute on Drug Abuse (NIDA)NCT05807139Written as Spironolactone
- A Phase IV, Two-part, Open-label Study Assessing the Pharmacokinetics, Safety and Pharmacodynamics of Spironolactone Oral Suspension in Pediatric PatientsNot yet recruitingPhase 4CMP Development, LLCNCT06021860Written as Spironolactone Oral Suspension
- Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of PregnancyRecruitingPhase 2Massachusetts General HospitalNCT07238400Written as Eplerenone 100 mg daily
- Spironolactone for Pulmonary Arterial HypertensionRecruitingPhase 2National Institutes of Health Clinical Center (CC)NCT01712620Written as Spironolactone
- Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical StudyRecruitingPhase 4Brigham and Women's HospitalNCT05030545Written as Eplerenone
- SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive TherapyNot yet recruitingPhase 4Ottawa Hospital Research InstituteNCT07687160Written as Spironolactone (drug)
- A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced MalignanciesRecruitingPhase 1Novartis PharmaceuticalsNCT07340190Written as drospirenone
- Cardiac Improvement by Eplerenone Among Patients Under Cyclosporine or Tacrolimus for Kidney Transplantation.Not yet recruitingPhase 3Central Hospital, Nancy, FranceNCT07828223Written as Eplerenone
- Regression in Left Ventricular Hypertrophy and Fibrosis in Aortic StenosisNot yet recruitingPhase 2University College, LondonNCT07539259Written as Spironolactone (drug)
- Eplerenone and IOP in Healthy AdultsNot yet recruitingPhase 1University of FloridaNCT07795762Written as Eplerenone
- Early Aldo Blockade in Subclinical PANot yet recruitingPhase 2/3Xinjiang Medical UniversityNCT07727252Written as Eplerenone
- Efficacy and Safety of Spironolactone in Pediatric Hemodialysis Patients With Anemia.Not yet recruitingPhase 2Ain Shams UniversityNCT07715318Written as Spironolactone (drug)
- HEART: Pilot Randomized Controlled TrialRecruitingPhase 1/2Mayo ClinicNCT07483177Written as Spironolactone
- Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in HypertensionRecruitingPhase 4Brigham and Women's HospitalNCT05593055Written as Eplerenone
- Spironolactone to Improve Pregnancy-Associated Hypertension TrajectoriesRecruitingPhase 2Massachusetts General HospitalNCT07041281Written as spironolactone 25 mg orally once daily
- A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First ProgressionNot yet recruitingPhase 1/2Starlight Therapeutics Inc.NCT07431216Written as Spironolactone (drug)
- Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery StudyRecruitingPhase 1/2Chulalongkorn UniversityNCT06345560Written as Drospirenone
- Drospirenone Only Pills and Cervical Mucus Changes: A Pre- and Post-Bariatric Surgery StudyRecruitingNot applicableChulalongkorn UniversityNCT06345586Written as Drospirenone
- Topical 5% Spironolactone Gel Versus 0.1% Adapalene Gel for Acne Vulgaris: A Randomized Split-Face StudyNot yet recruitingPhase 2Assiut UniversityNCT07473895Written as Spironolactone 5% Topical Gel
See all 312 studies that test one of the mineralocorticoid receptor antagonists →
Codes
What other systems call Mineralocorticoid Receptor Antagonists · ClinicalTrials.gg INT006921
- MeSH (NLM) D000451Mineralocorticoid Receptor AntagonistsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000451 | Mineralocorticoid Receptor Antagonists | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.