Mayo Clinic: Heart Failure trials

The registry lists 64 Heart Failure studies with Mayo Clinic as lead sponsor. 10 are open to participants now and 15 have results posted.

Early Phase 1 1Phase 1 11Phase 2 8Phase 3 3Phase 4 1No phase 44(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Community-Informed Interventions for Equitable Congestive Heart Failure Management in Primary CareRecruitingNCT07730827
• AI-Guided Left Bundle Branch Area PacingRecruitingNCT07206602Not applicable
• A Study of Paramedic HF ManagementRecruitingNCT06874556
• Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary HypertensionRecruitingNCT06770023Phase 1
• Rilonacept in Subjects With Cardiac SarcoidosisRecruitingNCT06660732Phase 2
• Inspiratory Muscle Training in HFpEFRecruitingNCT06510231Not applicable
• Contrast Echocardiography During Exercise to Assess Pulmonary Blood VolumeRecruitingNCT06195059
• A Study of the Effect of a Nurse Navigator Program on High Risk PatientsNot yet recruitingNCT05592847Not applicable
• TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast CancerRecruitingNCT05507879
• A Study to Evaluate Breathing Muscle Training in Cardiac RehabRecruitingNCT04984473Not applicable
• A Study of Ultra High Dose Diuretics to Treat Heart FailureCompletedNCT06036914Phase 2Results posted
• Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)CompletedNCT04938661Not applicableResults posted
• Dapagliflozin (DAPA) Effects in HFpEFCompletedNCT04730947Phase 2Results posted
• Assessment of Pulmonary Congestion During Cardiac Hemodynamic Stress TestingTerminatedNCT04019613Not applicableResults posted
• Myeloperoxidase (MPO) Inhibitor A_Zeneca for Heart Failure With Preserved Ejection Fraction (HFpEF)CompletedNCT03611153Phase 1/2Results posted
• Circulating NEP and NEP Inhibition Study in Heart Failure With Preserved Ejection FractionCompletedNCT03506412Phase 4Results posted
• Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled TrialCompletedNCT02885636Phase 3Results posted
• Spinal Stimulation During Exercise in Heart FailureTerminatedNCT02659202Not applicableResults posted
• Integrated Tele-monitoring and Patient-centric Health Coaching Strategy in Patients Hospitalized With Heart FailureCompletedNCT02391987Not applicableResults posted
• Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection FractionCompletedNCT02262078Phase 2Results posted
• Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart FailureCompletedNCT02145351Not applicableResults posted
• Tadalafil and Nesiritide as Therapy in Pre-clinical Heart FailureCompletedNCT01544998Phase 1/2Results posted
• The Effects of Decreasing the Lasix Dose on the Cardiorenal SystemCompletedNCT00982423Phase 1/2Results posted
• AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot StudyTerminatedNCT00589303Phase 3Results posted
• Strategies for Aggressive Central Afterload Reduction in Patients With Heart FailureCompletedNCT00588692Not applicableResults posted
• Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure RiskCompletedNCT05950399Not applicable
• Sleep Apnea in Heart Failure With Preserved Ejection FractionCompletedNCT05008432
• Effect of Rapamycin to Improve Cardiac Function in Frail Older AdultsCompletedNCT04996719Phase 1
• Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure PatientsSuspendedNCT04909008Not applicable
• Intravascular Volume Expansion to Neuroendocrine-Renal Function Profiles in Chronic Heart FailureCompletedNCT04156854Not applicable
• Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI)CompletedNCT04019314Not applicable
• ECG AI-Guided Screening for Low Ejection FractionCompletedNCT04000087Not applicable
• Respiratory Muscle Function in Heart FailureCompletedNCT03924479Not applicable
• Minimally Invasive Pericardiotomy as a New Treatment for Heart FailureCompletedNCT03923673Not applicable
• Biomarkers for Human Heart FailureCompletedNCT03905252
• The Utility of Focused Frailty Interventions on Patients With Advanced Heart FailureCompletedNCT03574662Not applicable
• Transthyretin Cardiac Amyloidosis in HFpEFCompletedNCT03414632Early Phase 1
• Cardiac Rehab for Advanced Heart Failure-LVAD CandidatesWithdrawnNCT03132441Not applicable
• Subcu Administration of CD-NP in Heart Failure Patients With Left Ventricular Assist Device SupportWithdrawnNCT03091998Phase 1
• Pericardial Resection to Treat Heart FailureCompletedNCT03073668Not applicable
• Safety and Efficacy of ANX-042 in Human Cardiorenal SyndromeCompletedNCT03019653Phase 1
• Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart FailureTerminatedNCT02783716Not applicable
• Reducing 30-day Readmissions in Patients With Heart Failure Through Pharmacist Discharge Medication ServicesCompletedNCT02752997Not applicable
• Impact of MayoExpertAdvisor on Provider AdherenceCompletedNCT02742545Not applicable
• Resistance Training in HFpEFCompletedNCT02435667Not applicable
• Mechanisms of Altered Ventilatory Control in Heart FailureCompletedNCT02421341Not applicable
• Chronic Obstructive Pulmonary Disease (COPD) in Patients Hospitalized for Acute Decompensated Heart Failure.WithdrawnNCT02340702
• Blood Volume and Hemodynamic Analysis in Patients With Chronic Heart FailureCompletedNCT02120014Not applicable
• Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community StudyActive, not recruitingNCT02047396
• Evaluation of the BodyGuardian End-to-end Remote Monitoring Platform in an Outpatient Heart Failure PopulationCompletedNCT01975402
• Assessment of the BodyGuardian Remote Monitoring Platform in Elderly Healthy SubjectsCompletedNCT01808053
• Myocardial Performance at Rest and During Exercise in Heart Failure With Preserved Ejection FractionTerminatedNCT01747785
• Cardiac Resynchronization and Iodine Meta-Iodobenzylguanidine (MIBG) ImagingTerminatedNCT01522378Phase 1
• Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular DiseaseCompletedNCT01418248
• Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal DysfunctionCompletedNCT00972569Phase 1/2
• Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal DysfunctionTerminatedNCT00818701Phase 1
• CD-NP in Subjects With Stable Chronic Heart FailureCompletedNCT00620308Phase 1
• BNP Measurement Reduces Resource Utilization for Patients With CHF Admitted Thorough the EDCompletedNCT00587938
• Mechanisms in Heart Failure With Normal EFCompletedNCT00587808
• Heart Failure and a Preserved Ejection FractionCompletedNCT00586833
• Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart FailureCompletedNCT00170183Phase 3
• Heart Failure in the CommunityCompletedNCT00053534
• Mapping Novel Disease Genes for Dilated CardiomyopathyCompletedNCT00046618
• Prevalence of Asymptomatic Ventricular DysfunctionCompletedNCT00005534