Drug
Vericiguat clinical trials
Also written Verquvo, MK-1242 and BAY 1021189.
- studies test it
- 33
- open now
- 14
- in phase 3
- 3
- first study started
- 2013
Keep track of what changes. Save the vericiguat studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Brand
Development codes
Studies by the year they started
33 studies that test it; most in 2023 (6)
| Year | Studies |
|---|---|
| 2013 | 2 |
| 2014 | 2 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 2 |
| 2021 | 2 |
| 2022 | 1 |
| 2023 | 6 |
| 2024 | 4 |
| 2025 | 5 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 7
- Phase 2
- 12
- Phase 3
- 3
- Phase 4
- 9
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 14 · Other 19
Bayer (11) · Merck Sharp & Dohme LLC (3) · Memorial Sloan Kettering Cancer Center (1) · Charite University, Berlin, Germany (1) · University of Colorado, Denver (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Johns Hopkins University (1) · Josef Stehlik (1)
Often tested with
Tested in the same studies.
Isosorbide mononitrate (1) · Nitroglycerin (1) · Moxifloxacin (1)
Studies
Open first, then newest update. How each study uses vericiguat is read from its arms, and is right about nine times in ten.
Testing it · 33
- Vericiguat and Reverse Remodeling Indices in Heart FailureRecruitingPhase 4University Medical Centre LjubljanaNCT07405944Written as Vericiguat
- Vericiguat for the Inhibition of Calcific Aortic Valve Stenosis ProgressionRecruitingPhase 2West China HospitalNCT07715279Written as Vericiguat (BAY1021189)
- Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)RecruitingPhase 2/3Merck Sharp & Dohme LLCNCT05714085Written as Vericiguat tablet
- COgnitioN With VERiciGuat Evaluation in Heart FailureRecruitingPhase 2University of AlbertaNCT06601465Written as Vericiguat
- SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac SurgeryRecruitingPhase 4Vanderbilt University Medical CenterNCT05812755Written as Vericiguat
- Comparing the Efficacy and Safety of Vericiguat With Standard Medical Treatment in Heart Failure PatientsNot yet recruitingPhase 4National Institute of Cardiovascular Diseases, PakistanNCT07697833Written as Vericiguat tablet
- Vericiguat in Patients With Coronary Microvascular Dysfunction Causing Stable Chest Pain (V-COM)RecruitingNot applicableThe University of Hong KongNCT06239974Written as Vericiguat
- Efficacy of Verciguat in TR and RV FailureNot yet recruitingPhase 4Daejeon St. Mary's hospitalNCT07668739Written as Vericiguat
- Perioperative Vericiguat in Patients Undergoing Cardiovascular SurgeryNot yet recruitingNot applicableNanjing Medical UniversityNCT07594509Written as Vericiguat
- Vericiguat in Decompensated Cardiac Failure: Clinical Insights on Addition to Guidelines Derived Medical Therapy-VERCIG TrialRecruitingPhase 1Khawaja Danish AliNCT07444398Written as Vericiguat tablet
- VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling PathwayNot yet recruitingPhase 2University of Alabama at BirminghamNCT06320951Written as Vericiguat 10 MG
- A Study of Real-world Events of Vericiguat in Patients With Chronic Kidney Disease and Heart FailureRecruitingNot applicableGuangdong Provincial People's HospitalNCT07047547Written as Vericiguat
- Efficacy and Safety of Early Initiation of Vericiguat in Heart Failure After Acute Myocardial InfarctionNot yet recruitingPhase 4Dongying ZhangNCT06812546Written as Vericiguat
- The CardioMEMS Vericiguat Heart Failure TrialNot yet recruitingPhase 4Finn GustafssonNCT06671990Written as Vericiguat
- A Study of Vericiguat in People With Breast Cancer and Cancer Therapy-Related Cardiac DysfunctionActive, not recruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT05806138Written as Vericiguat
- The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina PectorisCompletedPhase 2Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT06415227Written as Vericiguat
- Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 SyndromeActive, not recruitingPhase 2Charite University, Berlin, GermanyNCT05697640Written as Vericiguat Oral Tablet
- Vericiguat in Patients With Metabolic Syndrome and Coronary Vascular DysfunctionCompletedPhase 2Johns Hopkins UniversityNCT05711719Written as Vericiguat
- A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)CompletedPhase 3Merck Sharp & Dohme LLCNCT05093933Written as Vericiguat
- Impact of Vericiguat on Hemodynamics of Heart FailureActive, not recruitingPhase 4University of Colorado, DenverNCT05704478Written as Vericiguat
Codes
What other systems call vericiguat · ClinicalTrials.gg INT000367
- MeSH (NLM) C000603960vericiguatConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) LV66ADM269VERICIGUATConfirmed FDA, NLM, Wikidata
- RxNorm 2475830One source FDA
- Wikidata Q27283201vericiguatConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C152862VericiguatOne source FDA
- DrugBank DB15456One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000603960 | vericiguat | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | LV66ADM269 | VERICIGUAT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2475830 | — | One source FDA |
| Wikidata | Q27283201 | vericiguat | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C152862 | Vericiguat | One source FDA |
| DrugBank | DB15456 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.