Medtronic: Heart Failure trials

The registry lists 130 Heart Failure studies with Medtronic as lead sponsor. 4 are open to participants now and 59 have results posted.

Early Phase 1 1Phase 1 2Phase 2 3Phase 3 3Phase 4 14No phase 108(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area PacingRecruitingNCT07526896Not applicable
• ELEVATE-HFpEF Clinical StudyRecruitingNCT06678841Not applicable
• ContraBand™: Safety & Feasibility Study (RM-20-01)RecruitingNCT05230745Not applicable
• Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy ProductsRecruitingNCT00271180
• Crome/Cobalt Respiration StudyCompletedNCT06089694Results posted
• China 3T MRI StudyCompletedNCT06038123Not applicableResults posted
• Conduction System Pacing Optimized TherapyCompletedNCT04905290Not applicableResults posted
• Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart FailureCompletedNCT04452149Not applicableResults posted
• Mid-Q Response StudyCompletedNCT04180696Not applicableResults posted
• Apogee, A HeartWare HVAD Destination Product Surveillance Registry (PSR) PlatformCompletedNCT03697980Results posted
• Relationship Between LINQ™ Subcutaneous Impedance and Right-sided Hemodynamic MeasurementsCompletedNCT03608826Not applicableResults posted
• ECG Belt for CRT ResponseCompletedNCT03504020Not applicableResults posted
• REmodeling the Left Ventricle With Atrial Modulated PacingCompletedNCT03210402Not applicableResults posted
• Attain Stability™ Quad Clinical StudyCompletedNCT03099655Not applicableResults posted
• Pressure Variability StudyCompletedNCT02943941Not applicableResults posted
• Left Ventricular Synchronous Versus Sequential MultiSpot Pacing for Cardiac Resynchronization Therapy (CRT)CompletedNCT02914457Not applicableResults posted
• Reveal LINQ™ Heart FailureCompletedNCT02758301Results posted
• Integrated Diagnostics Driven Diuretic and Chronic Medication Management for Heart FailureTerminatedNCT02698241Not applicableResults posted
• Chronotropic Incompetence (CI) Diagnostic Algorithm in Heart Failure PatientsTerminatedNCT02358603Not applicableResults posted
• HW006 LATERAL ThoracotomyCompletedNCT02268942Not applicableResults posted
• Clinical Evaluation of HW005 Ventricular Assist System for the Treatment of Advanced Heart Failure in JapanCompletedNCT02091440Not applicableResults posted
• Mapping for Acute Transvenous Phrenic Nerve Stimulation StudyCompletedNCT01981590Not applicableResults posted
• A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)CompletedNCT01966458Not applicableResults posted
• Left Ventricular MultiSpot Pacing for CRT (iSPOT)CompletedNCT01883141Not applicableResults posted
• Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE TrialsCompletedNCT01832610Results posted
• Sensor Optimization of Cardiac Resynchronization Therapy ResponseCompletedNCT01832493Not applicableResults posted
• A Clinical Trial to Evaluate the HeartWare MVAD® System (MVAdvantage)TerminatedNCT01831544Not applicableResults posted
• Attain Performa(TM) Quadripolar Lead StudyCompletedNCT01751022Not applicableResults posted
• MIRACLE EF Clinical StudyTerminatedNCT01735916Not applicableResults posted
• REducing 30-day ADMIssions in posT-discharge Subjects (READMIT)CompletedNCT01574144Results posted
• Diagnostic Device Risk Management of Atrial Fibrillation and Heart FailureCompletedNCT01486316Not applicableResults posted
• Adaptive Cardiac Resynchronization Therapy Optimization at Rest and During Exercise (AdOPT CRT)TerminatedNCT01475175Not applicableResults posted
• Feasibility of an Integrated Patient Care (IPC) System Using Daily Filling PressuresCompletedNCT01370564Phase 2Results posted
• Leadless Electrocardiogram (ECG) Evaluation StudyCompletedNCT01297283Not applicableResults posted
• ALternate Site Cardiac ReSYNChronization (ALSYNC) StudyCompletedNCT01277783Not applicableResults posted
• The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE TrialCompletedNCT01166347Not applicableResults posted
• Determining the Feasibility of Spinal Cord Neuromodulation for the Treatment of Chronic Heart FailureCompletedNCT01112579Phase 2Results posted
• Model 4968 CAPTURE EPI® STERIOD-ELUTING BIPOLAR EPICARDIAL PACING LEAD Post-approval StudyCompletedNCT01076361Results posted
• Dual-Site LV Pacing in CRT Non Responders: Multicenter Randomized TrialCompletedNCT01059175Not applicableResults posted
• CareLink® Network EvaluationCompletedNCT01023022Results posted
• Attain Success Clinical TrialCompletedNCT00990964Results posted
• Adaptive Cardiac Resynchronization Therapy StudyCompletedNCT00980057Not applicableResults posted
• Model 4296 Left Ventricular (LV) Lead StudyCompletedNCT00927251Not applicableResults posted
• MOnitoring REsynchronization deviCes and cARdiac patiEntsTerminatedNCT00885677Not applicableResults posted
• Model 4396 Left Ventricular (LV) Lead StudyCompletedNCT00853593Not applicableResults posted
• OptiVol® Care PathwayCompletedNCT00847288Phase 4Results posted
• Evaluation of the HeartWare Left Ventricular Assist Device for the Treatment of Advanced Heart FailureCompletedNCT00751972Not applicableResults posted
• Chronicle Offers Management to Patients With Advanced Signs and Symptoms of Heart Failure (COMPASS-HF)CompletedNCT00643279Not applicableResults posted
• ConsultaTM CRT-D Clinical Evaluation StudyCompletedNCT00526162Not applicableResults posted
• Evaluation of Cardiac Compass With OptiVol in the Early Detection of Decompensation Events for Heart FailureTerminatedNCT00510198Not applicableResults posted
• Diagnostic Outcome Trial in Heart Failure (DOT-HF Trial)TerminatedNCT00480077Phase 4Results posted
• Sensitivity of the InSync Sentry OptiVol Feature for the Prediction of Heart FailureCompletedNCT00400985Not applicableResults posted
• Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)CompletedNCT00354159Not applicableResults posted
• CARE-HF Long Term Follow-upCompletedNCT00318357Results posted
• IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient SettingCompletedNCT00303979Results posted
• FAST (Fluid Accumulation Status Trial)CompletedNCT00289276Not applicableResults posted
• PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart FailureCompletedNCT00279955Results posted
• OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy Devices.TerminatedNCT00277524Results posted
• InSync Model 8040 (InSync) and InSync III Model 8042 (InSync III) RegistryCompletedNCT00273182Results posted
• Attain Model 4196 Left Ventricular (LV) LeadCompletedNCT00271544Not applicableResults posted
• REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)CompletedNCT00271154Not applicableResults posted
• Biventricular Versus Right Ventricular Pacing in Heart Failure Patients With Atrioventricular Block (BLOCK HF)CompletedNCT00267098Not applicableResults posted
• MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart FailureCompletedNCT00262119Phase 4Results posted
• Characterizing Outcomes and Real-World Experience of Cardiac Physiologic Pacing (The CORE-CPP Study)Active, not recruitingNCT06606288
• Bolt CSP-M Holter StudyActive, not recruitingNCT06540521
• HVAD(TM) SMART 1.0 StudyWithdrawnNCT04854200
• PLASMA Chile (PLASMA Chile)CompletedNCT04757142
• Electrogram and Hemodynamic Characteristics of Adaptive LBBAP in Patients With Heart Failure or BradycardiaCompletedNCT04738396
• Mechanical Circulatory Support Korea Post Market Surveillance Study (PMS)CompletedNCT04543747
• Personalized Therapy Study - HFRS (TriageHF) Post Approval StudyActive, not recruitingNCT04489225
• PLASMA Mexico (PLASMA Mexico)CompletedNCT04214899
• Apogee InternationalTerminatedNCT04065997
• Personalized Therapy Study - Attain Stability Quad Post-Approval StudyActive, not recruitingNCT04024943
• MDT-1118 Japan DT StudyCompletedNCT03884504Phase 3
• Personalized CRT - PSRCompletedNCT03723265
• Destination Therapy Post Approval StudyActive, not recruitingNCT03681210
• LINQ for impEdance meAsuremeNt While Off From HF Medication StudyStatus unknownNCT03245281Phase 4
• Personalized CRT - MPP Post Approval StudyCompletedNCT03232944
• Evaluation of Rate Adaptive Pacing on Chronotropic Response in Preserved Ejection Fraction HFWithdrawnNCT03160625Not applicable
• RESpiration deTection From Implanted Cardiac Devices in Subjects With Heart Failure (REST-HF)Status unknownNCT03087084Not applicable
• Application of Right Atrial Left Ventricular Fusion Pacing in Patients With CRT IndicationsCompletedNCT03071978Not applicable
• Assessment of AAIR Pacing Treatment for Heart Failure Patients With Chronotropic IncompetenceCompletedNCT03071952
• PRoMOTE Follow-up Observational StudyCompletedNCT03009175
• Attain Performa™ Left Ventricular (LV) Quadripolar Leads Chronic Performance StudyCompletedNCT02294331
• OneShot Renal Denervation RegistryTerminatedNCT01844037Phase 2/3
• Integrated Diagnostic for Heart FailureCompletedNCT01798797
• The Product Surveillance Registry REVERSE Post Approval StudyCompletedNCT01660035
• Cutaneous Heart Sounds Data Collection During Cardiac Resynchronization Therapy (CRT) Optimization StudyCompletedNCT01609985
• Impedance Measurements in Heart Failure PatientsTerminatedNCT01509495Phase 1
• Medtronic South Asian Systolic Heart Failure RegistryCompletedNCT01434615Phase 4
• Renal Denervation in Patients With Chronic Heart Failure & Renal Impairment Clinical TrialTerminatedNCT01392196Not applicable
• Model 20066 Left Ventricular (LV) Lead StudyCompletedNCT01365234Phase 1
• Characterization of Interventricular Conduction MeasurementsCompletedNCT01362465Early Phase 1
• Model 4396 Left Ventricular (LV) Lead Chronic Performance StudyCompletedNCT01361685
• Model 4296 Left Ventricular (LV) Lead Chronic Performance StudyCompletedNCT01361672
• Latin America Cardiac Resynchronization Therapy StudyStatus unknownNCT01238874Phase 4
• Cardiac Rhythm Monitoring After Acute Decompensation for Heart FailureCompletedNCT01216670
• Medtronic Observational Study in the "Real World" of Implantable Electronic Cardiac DevicesStatus unknownNCT01189630
• PhrenIc Nerve mappinG and Stimulation EP Catheter Study: PING-EP StudyCompletedNCT01109641Phase 4
• Feasibility Study of an Integrated Diagnostic System to Manage Heart FailureCompletedNCT01045343Not applicable