Hypotension clinical trials
The registry lists 885 studies for Hypotension across more than 10 countries. 195 are recruiting or about to start. 695 of them are mainly about Hypotension (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Hypotension, Orthostatic: 1,077 studies, 240 open.
ClinicalTrials.gov finds 1,474 studies for Hypotension. How that becomes 883 here
This page counts the studies the registry files under Hypotension, and those it files under no condition that list Hypotensionthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,474Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −192Filed under a narrower condition, counted on its own pageHypotension, Orthostatic 132 · Shy-Drager Syndrome 28 · Post-Exercise Hypotension 22
- −113List Hypotension as a condition, but the registry did not file them under itMost often written as “Intraoperative Hypotension” (28), “Intradialytic Hypotension” (12), and “Spontaneous Intracranial Hypotension” (9). The registry filed them under other conditions only, most often Acute Kidney Injury (15) and Intracranial Hypotension (14).
- −287Match it another way223 name it in the title, 34 in a keyword, and 30 by a synonym or other text the search reads.
- 882Counted here and found by its search245 of them list Hypotension in their own words; the registry filed them under no condition.
- +1
Counted here, but its search does not find them
- 883The count on this page
Get an email when these change. Save the Hypotension studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
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What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Cairo University (32) · Seoul National University Hospital (17) · Ain Shams University (16) · Assiut University (15) · Universitätsklinikum Hamburg-Eppendorf (11) · National Taiwan University Hospital (11) · Kasr El Aini Hospital (10) · Ankara City Hospital Bilkent (10)
What is being tested here
Drugs under test in Hypotension studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Norepinephrine | 11 | 7 | 48 |
| Phenylephrine | 5 | 2 | 39 |
| Midodrine | 3 | 3 | 9 |
| Ephedrine | 2 | 0 | 13 |
| Dexmedetomidine | 2 | 2 | 7 |
| Ondansetron | 1 | 6 | 14 |
| Epinephrine | 1 | 0 | 7 |
| Propofol | 1 | 1 | 5 |
| Arginine Vasopressin | 1 | 0 | 5 |
| Dexamethasone | 1 | 2 | 4 |
Drug classes tested here Corticosteroids 2 open · Antiemetics 1 open · 5-HT3 antagonists 1 open · Local anesthetics 1 open · Beta blockers 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor · Phase 3 · Vanderbilt University Medical Center
- Nov 2026Comparison of Classic and Sequential Spinal Techniques for Preventing Hypotension During Cesarean Delivery. · Phase 3 · Al-Azhar University
- Dec 2026Role of Ondansetron in Spinal Anaesthesia Induced Hypotension · Phase 3 · Assiut University
- Dec 2026Early Initiated Vasopressor Therapy in the Emergency Department · Phase 3 · Odense University Hospital
- Apr 2027Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room · Phase 3 · Nantes University Hospital
- Jun 2027Noradrenaline Versus Standard Blood Pressure Management for Perioperative Hypotension in Non-cardiac Surgery · Phase 3 · Jagiellonian University
- Nov 2026Vasopressor SAT Study · University of Chicago
- Nov 2026Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery · Universitätsklinikum Hamburg-Eppendorf
- Nov 2026Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP · Istanbul University
- Nov 2026The Noninvasive Blood Pressure Measurement Effect on the Hypotension · Konya City Hospital
Who these studies take
Of the 111 Hypotension studies recruiting now, 50 (45%) set no upper age limit and 36 (32%) stop at 75 or younger. 7 (6%) take children under 18. 20 (18%) are for women only and 2 (2%) for men only; 15 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (2%) | 1 (1%) |
| 18 | 67 (60%) | 52 (47%) |
| 30 | 79 (71%) | 61 (55%) |
| 40 | 79 (71%) | 63 (57%) |
| 50 | 69 (62%) | 68 (61%) |
| 65 | 85 (77%) | 84 (76%) |
| 75 | 77 (69%) | 76 (68%) |
| 85 | 62 (56%) | 61 (55%) |
Across all 885 studies, recruiting or not: 37% stop at 75 or younger and 33% at 65; 8% take children; 27% are for women only and 1% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypotension studies take
Of 61 phase 4 interventional studies under Hypotension, half reached primary completion within 12 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 22 mo10–37 · 23 studies | — | — |
| Phase 4 | 12 mo5–20 · 61 studies | — | 12 mo5–20 · 60 studies |
| Interventional, no phase | 12 mo6–22 · 217 studies | — | 12 mo6–22 · 210 studies |
| Observational | 11 mo5–24 · 151 studies | — | 12 mo5–25 · 146 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting2
Stopped1
- Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast ReconstructionTerminatedOct 28, 2026NCT06080178
Newly registered10
- Intrathecal Dexmedetomidine 5 mcg Versus 10 mcg With Bupivacaine for Infra-umbilical SurgeryNov 10, 2026NCT07929818
- In Elderly Patients, Does Goal-directed Fluid Management Using the Carotid Corrected Flow Time (CC-FT) Index, Compared to Routine Fluid Management, Affect the Occurrence of Post-induction Hypotension?Nov 9, 2026NCT07925918
- Diastolic Shock Index for Predicting Hemodynamic Instability During Continuous Renal Replacement TherapyNov 5, 2026NCT07918742
- OB VEGA-Phenylephrine vs Norepinephrine OutcomesOct 28, 2026NCT07900919
- Cardiac Arrest - Ultrasound Detection of Occult PerfusionOct 27, 2026NCT07897370
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- Haemodynamic Effects of Four Sevoflurane Wash-In Strategies After Tracheal IntubationOct 26, 2026NCT07894393
- ED90 of Norepinephrine and Phenylephrine Infusion in Patients of Advanced Maternal AgeOct 26, 2026NCT07894783
- Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean SectionOct 21, 2026NCT07886151
- Prophylactic Ondansetron and Maternal Hemodynamics During Spinal Anesthesia for Elective Cesarean SectionOct 20, 2026NCT07883772
- Oliceridine Versus Sufentanil for Blood Pressure Control During Anesthesia Induction in Older Women With Hypertension Undergoing Gynecological Laparoscopic SurgeryOct 13, 2026NCT07871500
Studies
Recruiting first, then most recently updated. Showing 50 of 885. Browse all 885 → or search them.
- In Elderly Patients, Does Goal-directed Fluid Management Using the Carotid Corrected Flow Time (CC-FT) Index, Compared to Routine Fluid Management, Affect the Occurrence of Post-induction Hypotension?Not yet recruitingNCT07925918Not applicable
- Norepinephrine in the Management of General Anesthesia-Induced Arterial Hypotension in Chronic Heart Failure PatientsRecruitingNCT063509291 country
- Diastolic Shock Index for Predicting Hemodynamic Instability During Continuous Renal Replacement TherapyNot yet recruitingNCT079187421 country
- Remimazolam Versus Propofol for Maintenance of Anaesthesia During Major Hepatectomy Under Low Central Venous PressureRecruitingNCT07789275Phase 41 country
- Effect of Ondansetron on the Incidence of Spinal Anaesthesia-Induced Hypotension in Elderly Patients Undergoing Fracture Hip SurgeryNot yet recruitingNCT07914868Phase 41 country
- Applying HPI in Oral Cancer SurgeryNot yet recruitingNCT07405892Not applicable
- Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor SurgeryRecruitingNCT077771591 country
- Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal SurgeryRecruitingNCT06753409Not applicable1 country
- The Role of Preoperative Internal Jugular Vein Collapsibility and Perfusion Index in Predicting Hypotension After Spinal Anesthesia in Elective Cesarean Sections: A Prospective Observational StudyRecruitingNCT075398961 country
- OB VEGA-Phenylephrine vs Norepinephrine OutcomesNot yet recruitingNCT07900919Phase 41 country
- Intelligent Classification of Intraoperative Hemodynamic Phenotypes Based on CADFlow Doppler MonitoringNot yet recruitingNCT069575871 country
- Cardiac Arrest - Ultrasound Detection of Occult PerfusionRecruitingNCT078973701 country
- ED90 of Norepinephrine and Phenylephrine Infusion in Patients of Advanced Maternal AgeNot yet recruitingNCT07894783Not applicable
- Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean DeliveryRecruitingNCT07379710Phase 41 country
- Comparison of HPI-guided Norepinephrine Boluses, ClearSight-guided Norepinephrine Infusion, and Oscillometric-guided Norepinephrine Infusion for Blood Pressure Stability During Cesarean DeliveryNot yet recruitingNCT07883265Not applicable1 country
- The Hypotension Prediction Index Versus Standard Advanced Haemodynamic Monitoring in Patients Undergoing Major Aortic SurgeryRecruitingNCT07510451Not applicable1 country
- Effects of Ondansetron Timing During Spinal Anesthesia for Urologic SurgeryNot yet recruitingNCT07858149Phase 41 country
- Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean DeliveryRecruitingNCT076787231 country
- Carotid Ultrasound for Post-Spinal Anesthesia Hypotension in Elderly Hip SurgeryNot yet recruitingNCT078760631 country
- Pre-induction Norepinephrine in Septic Patients Undergoing SurgeryNot yet recruitingNCT07869693Not applicable
- Trial of Variable Dialysate BicarbonateRecruitingNCT05814146Not applicable1 country
- Preoperative Point of Care Ultrasound Guided Fluid Optimization and Intravenous Ondansetron to Prevent General Anesthesia-Induced HypotensionNot yet recruitingNCT05784350Not applicable1 country
- Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 YearsNot yet recruitingNCT07847203
- Granisetron Use, Blood Pressure, and Nausea and Vomiting During Cesarean Delivery Under Spinal AnesthesiaNot yet recruitingNCT078617371 country
- Dural Sac Area-Guided Spinal Anesthesia Dosing for TURPEnrolling by invitationNCT07794852Not applicable1 country
- Modified Saddle Block vs Spinal Anesthesia for TURPRecruitingNCT07841184Phase 41 country
- Feasibility Study of E-Fusion Vasopressor Titration-Assist During Multi-Level Spine SurgeryNot yet recruitingNCT07840937Not applicable1 country
- Noradrenaline Versus Standard Blood Pressure Management for Perioperative Hypotension in Non-cardiac SurgeryRecruitingNCT06885268Phase 31 country
- The Relationship Between Hypotension and Tissue O2 in Invasive Eadyn During Anesthesia Induction in Open Heart SurgeryRecruitingNCT078312521 country
- Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal SurgeriesRecruitingNCT04914234Phase 41 country
- ED50/ED90 of Phenylephrine Infusion for Preventing Spinal Anesthesia-Induced Hypotension: Supine vs Left-Tilt 15°Not yet recruitingNCT07824713Phase 41 country
- Frequency of Electrical Acupoint Stimulation on Hypotension During InductionNot yet recruitingNCT07433218Not applicable
- Preoperative Neutrophil-to-Albumin Ratio and Post-Induction Hemodynamic Vulnerability in Major Oncologic SurgeryRecruitingNCT078047061 country
- Midodrine in Heart Failure With Reduced Ejection Fraction With HypotensionRecruitingNCT06405555Phase 2/31 country
- Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS)Not yet recruitingNCT07796282Phase 41 country
- MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) TrialRecruitingNCT06319248Phase 21 country
- Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean SectionNot yet recruitingNCT07789756Not applicable1 country
- Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal AnaesthesiaNot yet recruitingNCT07784478Not applicable1 country
- TSCS for Acute SCIRecruitingNCT05305118Not applicable1 country
- Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)RecruitingNCT07322133Phase 41 country
- Peripheral pULSe Assessment and Arterial pRessure (PULSAR)RecruitingNCT076090951 country
- Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Consequence and Intraoperative Indicator of Fluid ResponsivenessNot yet recruitingNCT07766967Not applicable1 country
- Blood'up Device Versus Manual Palpation for Arterial Puncture in Healthy Volunteers: A Pilot Randomized Study Under Normal and Simulated HypotensionNot yet recruitingNCT07765199Not applicable1 country
- Diastolic Shock Index for Predicting Postspinal HypotensionNot yet recruitingNCT07765342
- Treatment of Orthostatic Hypotension in SCIRecruitingNCT05839652Phase 41 country
- Perfusion Index and Spinal Hypotension in Day-Case Knee ArthroscopyRecruitingNCT077474411 country
- Intermittent Ephedrine Boluses for Prophylaxis Against Postinduction HypotensionRecruitingNCT07722013Not applicable1 country
- 5 Versus 10 mcg Norepinephrine Bolus in Treatment of Postinduction and Early Intraoperative Hypotension in Emergency Abdominal SurgeryRecruitingNCT07719075Not applicable1 country
- Prediction of Post-Induction Hypotension Using Plethysmographic Variability Index During Diagnostic LaryngoscopyNot yet recruitingNCT07458893
- Internal Jugular Vein Collapsibility Index for Predicting Post-Induction HypotensionNot yet recruitingNCT075650251 country