Shy-Drager Syndrome clinical trials
The registry lists 33 studies for Shy-Drager Syndrome across more than 10 countries. 15 are recruiting or about to start. 9 of them are mainly about Shy-Drager Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-08-28.
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Who runs them
Vanderbilt University (3) · Alterity Therapeutics (2) · Massachusetts General Hospital (2) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (2) · University of Oxford (2) · University of Michigan (1) · Kessler Foundation (1) · MD Stem Cells (1)
What is being tested here
Drugs under test in Shy-Drager Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Nov 2026Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury · Kessler Foundation
- Nov 2026Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease. · Julien Bally
- Apr 2027Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Jul 2027Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot Phase · MODAG GmbH
- Jul 2027Neurologic Stem Cell Treatment Study · MD Stem Cells
Who these studies take
Of the 12 Shy-Drager Syndrome studies recruiting now, 7 (58%) set no upper age limit and 2 (17%) stop at 75 or younger. 2 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (42%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (17%) | 2 (17%) |
| 18 | 9 (75%) | 9 (75%) |
| 30 | 10 (83%) | 10 (83%) |
| 40 | 11 (92%) | 11 (92%) |
| 50 | 12 (100%) | 12 (100%) |
| 65 | 12 (100%) | 12 (100%) |
| 75 | 12 (100%) | 12 (100%) |
| 85 | 10 (83%) | 10 (83%) |
Across all 33 studies, recruiting or not: 18% stop at 75 or younger and 6% at 65; 9% take children; 0% are for women only and 0% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 33 of 33. search them.
- Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot PhaseRecruitingNCT07640542Early Phase 11 country
- Remote Monitoring in Progressive Supranuclear Palsy (PSP)Not yet recruitingNCT047533201 country
- Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's DiseaseRecruitingNCT06920134Not applicable1 country
- Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord InjuryRecruitingNCT06841198Not applicable1 country
- Neurologic Stem Cell Treatment StudyRecruitingNCT02795052Not applicable2 countries
- Invasive Home Ventilation in DenmarkRecruitingNCT074671871 country
- Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic DisordersRecruitingNCT07509125Not applicable1 country
- Autologous Stem Cell Therapy in Patients With Multiple System AtrophyNot yet recruitingNCT07465198Phase 21 country
- Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease.RecruitingNCT06831500Phase 1/21 country
- The CurePSP Genetics ProgramRecruitingNCT066476411 country
- Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related DisordersEnrolling by invitationNCT046801301 country
- The STAND-UP StudyRecruitingNCT07195903Not applicable1 country
- [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD Vs. MSA and DLB Vs. ADRecruitingNCT06120049Phase 2/31 country
- Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement DisordersRecruitingNCT054868061 country
- Modifiable Variables in Parkinsonism (MVP)RecruitingNCT021948161 country
- Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body DiseaseActive, not recruitingNCT068466581 country
- Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)Active, not recruitingNCT05792332Not applicable1 country
- MotIoN aDaptive Deep Brain Stimulation for MSACompletedNCT05197816Not applicable1 country
- Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System AtrophyActive, not recruitingNCT05696717Phase 320 countries
- A Biomarker Study of ATH434 in Participants With MSACompletedNCT05864365Phase 21 country
- Dual Sympathetic Blocks for Patients Experiencing Sympathetically-Mediated Symptoms From Long COVIDCompletedNCT05638620Phase 11 country
- Study to Evaluate Investigational Allogeneic Cell Therapy Product hOMSC300 for Treatment of Early to Moderate Stage Multiple System Atrophy (MSA)Active, not recruitingNCT05698017Phase 11 country
- Study of ATH434 in Participants with Multiple System AtrophyCompletedNCT05109091Phase 26 countries
- Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech AnalysisCompletedNCT03577483Not applicable1 country
- Manipulating and Optimising Brain Rhythms for Enhancement of SleepCompletedNCT05011773Not applicable1 country
- Water and Sudafed in Autonomic FailureTerminatedNCT02149901Early Phase 11 country
- Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic FailureTerminatedNCT02591173Early Phase 11 country
- Spinal Cord Stimulation and Autonomic Response in People With SCI.Status unknownNCT03924388Not applicable1 country
- PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)CompletedNCT020357611 country
- The Autonomic Nervous System and ObesityCompletedNCT00179023Phase 11 country
- Treatment of Supine Hypertension in Autonomic FailureCompletedNCT00223717Phase 11 country
- Fipamezole in Neurogenic Orthostatic HypotensionStatus unknownNCT00758849Phase 22 countries
- Droxidopa in Treating Patients With Neurogenic HypotensionCompletedNCT00004478Not applicable1 country