Drug
Norepinephrine clinical trials
Also written Noradrenaline and Levophed.
- studies test it
- 177
- open now
- 43
- in phase 3
- 30
- first study started
- 1999
Keep track of what changes. Save the Norepinephrine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Other names
Studies by the year they started
177 studies that test it; most in 2022 (20)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2003 | 1 |
| 2006 | 2 |
| 2008 | 3 |
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 4 |
| 2012 | 5 |
| 2013 | 1 |
| 2014 | 9 |
| 2015 | 5 |
| 2016 | 11 |
| 2017 | 12 |
| 2018 | 8 |
| 2019 | 15 |
| 2020 | 11 |
| 2021 | 11 |
| 2022 | 20 |
| 2023 | 16 |
| 2024 | 13 |
| 2025 | 13 |
| 2026 | 14 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 6
- Phase 1
- 7
- Phase 2
- 12
- Phase 3
- 30
- Phase 4
- 55
- No phase
- 75
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 3 · Other 174
General Hospital of Ningxia Medical University (14) · Cairo University (12) · Kasr El Aini Hospital (6) · Sahlgrenska University Hospital (5) · Assiut University (5) · Samuel Lunenfeld Research Institute, Mount Sinai Hospital (4) · Tanta University (3) · University Tunis El Manar (3)
Often tested with
Tested in the same studies.
Phenylephrine (39) · Ephedrine (14) · Arginine Vasopressin (9) · Dopamine (7) · Epinephrine (6) · Terlipressin (5) · Nitroprusside (4) · Phentolamine (4)
Studies
Open first, then newest update. How each study uses Norepinephrine is read from its arms, and is right about nine times in ten.
Testing it · 177
- Low-Dose Norepinephrine With Conservative Fluid Therapy in Hepatobiliary SurgeryNot yet recruitingNot applicableAssiut UniversityNCT07892586Written as Low-Dose Norepinephrine
- Phenotype Guided Vasoactive Medication During Kidney TransplantationEnrolling by invitationPhase 4Jennifer CutlerNCT07633600Written as Phenotype-Guided Vasoactive Management
- Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean DeliveryRecruitingPhase 4Cairo UniversityNCT07379710Written as Ephedrine and Norepinephrine infusion
- Pre-induction Norepinephrine in Septic Patients Undergoing SurgeryNot yet recruitingNot applicableAssiut UniversityNCT07869693Written as Norepinephrine
- Assessing Catecholamine Treatment Initiation Options: Norepinephrine vs Dopamine for Cardiogenic ShockRecruitingNot applicableChonnam National University HospitalNCT07562932Written as Norepinephrine
- : Vascular Function in Health and DiseaseRecruitingPhase 1D. Walter WrayNCT02966665Written as Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine
- Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS)Not yet recruitingPhase 4Mayo ClinicNCT07796282Written as Norepinephrine bitartrate infusion
- Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)RecruitingPhase 4University of California, DavisNCT07322133Written as Norepinephrine
- 5 Versus 10 mcg Norepinephrine Bolus in Treatment of Postinduction and Early Intraoperative Hypotension in Emergency Abdominal SurgeryRecruitingNot applicableCairo UniversityNCT07719075Written as Norepinephrine 10 mcg
- Sex Disparities in Hypoxic Vasodilation and Impact of ObesityRecruitingEarly Phase 1University of Missouri-ColumbiaNCT05219799Written as Norepinephrine
- This is a Study That Aims to Estimate the Effect of Maternal Body Mass Index on the Prophylactic Dose of Norepinephrine Infusion for Preventing Hypotension in Parturient After Spinal AnesthesiaNot yet recruitingNot applicableAin Shams UniversityNCT07706426Written as Nor-epinephrine
- PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal SurgeryNot yet recruitingNot applicableSuez Canal UniversityNCT07627360Written as Norepinephrine
- Vasopressor Agents in Pulmonary Hypertension CrisisNot yet recruitingNot applicableChina National Center for Cardiovascular DiseasesNCT07667829Written as Norepinephrine
- Comparison of Norepinehrine Versus Phenylepherine Infusion for Prevention of Post-spinal HypotensionRecruitingPhase 4Sohag UniversityNCT07662408Written as Norepinephrine
- Hot Flashes and Neurovascular Function in WomenRecruitingNot applicableMayo ClinicNCT05193968Written as Norepinephrine
- The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac SurgeryRecruitingPhase 4University of California, San FranciscoNCT06802224Written as Norepinephrine
- Low-dose Norepinephrine Infusion for Prevention of Post-induction Hypotension in Emergency Surgery for PeritonitisNot yet recruitingPhase 4Bach Mai HospitalNCT07529795Written as Norepinephrine (0.05 μg/kg/min)
- Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro StudyRecruitingNot applicableSamuel Lunenfeld Research Institute, Mount Sinai HospitalNCT06285396Written as Norepinephrine
- Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro StudyRecruitingNot applicableSamuel Lunenfeld Research Institute, Mount Sinai HospitalNCT04053478Written as Norepinephrine
- Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During AnesthesiaRecruitingPhase 2/3University of AarhusNCT06083948Written as Noradrenalin
See all 177 studies that test Norepinephrine →
Given in every arm · 13 — Norepinephrine is usual care beside what is tested
- The Effect of Vasopressor Therapy on Renal Perfusion in Septic ShockRecruitingNot applicableKing's College Hospital NHS TrustNCT06234592Written as Norepinephrine
- Ventriculo-arterial Coupling and Myocardial Work in Sepsis and Septic ShockNot yet recruitingNot applicableGeneral and Teaching Hospital CeljeNCT06853574Written as Noradrenaline infusion
- Hypotension Prediction Index vs Norepinephrine Infusion for Prevention of Spinal Hypotension for Cesarean DeliveryNot yet recruitingPhase 4Fondazione Policlinico Universitario Agostino Gemelli IRCCSNCT05970770Written as Norepinephrine
- Angiotensin 2 for AKI After OLTActive, not recruitingPhase 4University of California, Los AngelesNCT04592744Written as Norepinephrine
- Dobutamine for Management of Surgical Patients With Septic ShockCompletedNot applicableFirst Affiliated Hospital of Zhejiang UniversityNCT06462313Written as Norepinephrine
- Leg Wrapping and Norepinephrine for Prevention of Post Spinal Hypotension in C.SCompletedPhase 4Fayoum UniversityNCT06496061Written as Norepinephrine
- HPI Algorithm for the Prevention of IOH During Spinal Surgery [HPIFPIOH]CompletedNot applicableAttikon HospitalNCT05341167Written as Vasoactive Agent
- Methylene Blue and Microcirculation in Septic ShockStatus unknownPhase 3Cairo UniversityNCT04295993Written as Norepinephrine infusion
- Decision Support for Intraoperative Low Blood PressureCompletedNot applicableVanderbilt University Medical CenterNCT02726620Written as Norepinephrine
- Angiotensin II for Septic Shock TreatmentSuspendedPhase 3Cairo UniversityNCT03302650Written as Norepinephrine
- NOrepinephrine and VasoprEssin Versus Norepinephrine aLone in Critically Ill Patients With Septic ShockWithdrawnPhase 4University of ArkansasNCT02454348Written as Norepinephrine
- To Assess the Efficacy of Early Introduction of a Combination of Low Dose Vasopressin Analogue in Addition to Noradrenaline as a Vasopressor in Patients of Cirrhosis With Septic ShockCompletedNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT02468063Written as Noradrenaline
- Interaction of Apelin and Angiotensin in the Human Forearm CirculationCompletedNot applicableUniversity of EdinburghNCT00901745Written as Noradrenaline infusion
As the comparator · 15 — what is tested is compared with Norepinephrine
- Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic ShockNot yet recruitingPhase 4Wake Forest University Health SciencesNCT06746753Written as Norepinephrine
- Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery,Not yet recruitingPhase 2Fondation Hôpital Saint-JosephNCT07614438Written as Norepinephrine
- Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial)RecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT06344442Written as Norepinephrine
- Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin IIRecruitingPhase 3Universität MünsterNCT06615102Written as Noradrenalin
- Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac SurgeryRecruitingPhase 4University of Sao PauloNCT06934798Written as Norepinephrine intravenous infusion
- Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal CirculationActive, not recruitingPhase 3Centre Hospitalier Universitaire DijonNCT05568160Written as Norepinephrine
- Vasopressin or Norepinephrine in Vasoplegic Shock After Non-cardiac SurgeryWithdrawnPhase 2/3University of Sao PauloNCT03483753Written as Norepinephrine
- The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic PerformanceStatus unknownPhase 4Medical University of ViennaNCT05492968Written as Norepinephrine
- Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal SyndromeCompletedNot applicableNational Hepatology & Tropical Medicine Research InstituteNCT04522297Written as Nor-epinephrine
- Phenylephrine in Septic ShockCompletedPhase 2University of Roma La SapienzaNCT00639015Written as Norepinephrine
- Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care UnitCompletedNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT01836224Written as Noradrenaline
- Continuos Terlipressin Infusion in Septic ShockStatus unknownNot applicableFirst Affiliated Hospital, Sun Yat-Sen UniversityNCT01697410Written as Norepinephrine
- The Effect of Terlipressin on Intesitnal Function in Septic Shock PatientsStatus unknownNot applicableLiu ZiMengNCT02306239Written as Norepinephrine
- Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Abdominal SurgeryCompletedPhase 4Klinikum LudwigshafenNCT00549419Written as Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine
- Continuous Infusion of Terlipressin in Septic ShockCompletedPhase 2University of Roma La SapienzaNCT00481572Written as Norepinephrine
Codes
What other systems call Norepinephrine · ClinicalTrials.gg INT007907
- MeSH (NLM) D009638NorepinephrineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) X4W3ENH1CVNOREPINEPHRINEConfirmed FDA, NLM, Wikidata
- RxNorm 7512Confirmed FDA, Wikidata
- Wikidata Q186242norepinephrineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C2321l-NorepinephrineOne source FDA
- DrugBank DB00368One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009638 | Norepinephrine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | X4W3ENH1CV | NOREPINEPHRINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7512 | — | Confirmed FDA, Wikidata |
| Wikidata | Q186242 | norepinephrine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C2321 | l-Norepinephrine | One source FDA |
| DrugBank | DB00368 | — | One source Wikidata |
Also registered as noradrenaline hydrochloride (UNII 4W6461XR05 · RxNorm 2256931) and norepinephrine bitartrate (UNII IFY5PE3ZRW · RxNorm 7508).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.