Drug
Midodrine clinical trials
Also written ProAmatine and Gutron.
- studies test it
- 72
- open now
- 7
- in phase 3
- 13
- first study started
- 1997
Keep track of what changes. Save the Midodrine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Brand
Studies by the year they started
72 studies that test it; most in 2020 (10)
| Year | Studies |
|---|---|
| 1997 | 2 |
| 1999 | 1 |
| 2001 | 1 |
| 2002 | 5 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2007 | 1 |
| 2008 | 1 |
| 2010 | 2 |
| 2011 | 3 |
| 2012 | 4 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 2 |
| 2016 | 6 |
| 2017 | 5 |
| 2018 | 4 |
| 2020 | 10 |
| 2021 | 6 |
| 2022 | 3 |
| 2023 | 2 |
| 2024 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 10
- Phase 2
- 16
- Phase 3
- 13
- Phase 4
- 19
- No phase
- 20
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 10 · Other 62
Institute of Liver and Biliary Sciences, India (10) · James J. Peters Veterans Affairs Medical Center (7) · Shire (5) · Vanderbilt University Medical Center (3) · Mylan Pharmaceuticals Inc (3) · University of Alberta (3) · Mayo Clinic (3) · Post Graduate Institute of Medical Education and Research, Chandigarh (2)
Often tested with
Tested in the same studies.
Octreotide (7) · Albumins (4) · Pyridostigmine (3) · Acetazolamide (2) · Atomoxetine (2) · Indomethacin (2) · Modafinil (2) · Norepinephrine (2)
Studies
Open first, then newest update. How each study uses Midodrine is read from its arms, and is right about nine times in ten.
Testing it · 72
- Midodrine in Heart Failure With Reduced Ejection Fraction With HypotensionRecruitingPhase 2/3Ottawa Heart Institute Research CorporationNCT06405555Written as Midodrine Oral Tablet
- MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) TrialRecruitingPhase 2Mayo ClinicNCT06319248Written as Midodrine
- Treatment of Orthostatic Hypotension in SCIRecruitingPhase 4James J. Peters Veterans Affairs Medical CenterNCT05839652Written as Midodrine Hydrochloride
- Carvedilol and Midodrine Versus Carvedilol Alone in Preventing Early Rebleed in Patients With Cirrhosis.Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT07465471Written as Midodrine Oral Product
- Efficacy and Safety of Early Initiation of Midodrine for Control and Prevention of Ascites and Its Related Complications in Acute-on-chronic Liver Failure.Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT07422948Written as Midodrine
- Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)RecruitingPhase 4University of AlbertaNCT05058612Written as Midodrine
- Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical TrialNot yet recruitingNot applicableSohag UniversityNCT06213935Written as Midodrine
- Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic FailureTerminatedPhase 1Vanderbilt University Medical CenterNCT02897063Written as Midodrine
- Treatment of Orthostatic IntoleranceActive, not recruitingPhase 1/2Satish R. RajNCT00262470Written as Midodrine
- Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure PatientsCompletedEarly Phase 1Vanderbilt University Medical CenterNCT04620382Written as Midodrine
- Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic FailureCompletedPhase 1Vanderbilt University Medical CenterNCT02429557Written as midodrine
- Pharmacological Enhancement of Glymphatic Function in HumansCompletedPhase 1/2Applied CognitionNCT07432997Written as Dexmedetomidine and Midodrine
- Midodrine Use in Septic ShockTerminatedPhase 3University of VirginiaNCT03706053Written as Midodrine Hydrochloride
- Thermoregulation and Cognition During Cool Ambient Exposure in TetraplegiaCompletedPhase 4James J. Peters Veterans Affairs Medical CenterNCT02379156Written as Midodrine Hydrochloride
- Midodrine Effect on the Mortality Rates in Septic Shock PatientsCompletedPhase 2Noha MansourNCT05778838Written as Midodrine Oral Tablet
- Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord InjuryCompletedPhase 3James J. Peters Veterans Affairs Medical CenterNCT02307565Written as Midodrine
- Treatment of Post-SCI HypotensionCompletedPhase 2/3James J. Peters Veterans Affairs Medical CenterNCT02919917Written as Midodrine Hydrochloride
- The Effects of Normalizing Blood Pressure on Cerebral Blood Flow in Hypotensive Individuals With Spinal Cord InjuryCompletedPhase 2James J. Peters Veterans Affairs Medical CenterNCT02893553Written as Midodrine Hydrochloride
- Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IVActive, not recruitingPhase 4Dr. Bob SheldonNCT01456481Written as midodrine hydrochloride
- Efficacy and Safety of Midodrine in Refractory or Recurrent Ascites in Children With Cirrhosis.WithdrawnNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT05084534Written as Midodrine
See all 72 studies that test Midodrine →
Given in every arm · 3 — Midodrine is usual care beside what is tested
- Evaluation of Low-dose Albumin and Midodrine Versus Midodrine Alone in Outcome of Recurrent Ascites in Patients With Decompensated Cirrhosis.Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT06245590Written as Midodrine
- Automated Abdominal Binder for Orthostatic HypotensionCompletedPhase 1/2Vanderbilt University Medical CenterNCT03482297Written as Midodrine
- Midodrine Plus Albumin Versus Midodrine Alone to Prevent Cirrhosis Related Complications in Children With Cirrhosis and AscitesCompletedNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT06091345Written as Midodrine
As the comparator · 4 — what is tested is compared with Midodrine
- Treatment Strategy of Vasovagal SyncopeRecruitingNot applicableChina National Center for Cardiovascular DiseasesNCT05803148Written as Midodrine Oral Tablet
- Angiotensin 2 for Hepatorenal SyndromeWithdrawnPhase 2University of California, Los AngelesNCT04048707Written as Midodrine
- Efficacy and Safety of Midodrine and Atomoxetine for Neurogenic OHCompletedPhase 4Seoul National University HospitalNCT03350659Written as Midodrine
- Efficacy and Safety of Terlipressin With Albumin Versus Midodrine With Albumin Versus Albumin Alone in Prevention of Paracentesis Induced Circulatory Dysfunction in CirrhosisCompletedNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT03144713Written as Midodrine
Codes
What other systems call Midodrine · ClinicalTrials.gg INT007835
- MeSH (NLM) D008879MidodrineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6YE7PBM15HMIDODRINEConfirmed FDA, NLM, Wikidata
- RxNorm 6963Confirmed FDA, Wikidata
- Wikidata Q415051midodrineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61846MidodrineOne source FDA
- DrugBank DB00211One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D008879 | Midodrine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6YE7PBM15H | MIDODRINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6963 | — | Confirmed FDA, Wikidata |
| Wikidata | Q415051 | midodrine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61846 | Midodrine | One source FDA |
| DrugBank | DB00211 | — | One source Wikidata |
Also registered as midodrine hydrochloride (UNII 59JV96YTXV · RxNorm 993491).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.