An observational study in Post-induction Hypotension (PIH) and Gastrointestinal Tumor Surgery, sponsored by Ankara City Hospital Bilkent. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-28.
Sponsored by Ankara City Hospital Bilkent · Observational
This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid artery Doppler parameters.
The study will be conducted on patients scheduled for elective gastrointestinal tumor surgery. Prior to anesthesia induction, a passive leg raise maneuver will be performed. Carotid artery Doppler parameters and hemodynamic changes will be measured and recorded to evaluate their efficacy in predicting subsequent post-induction hypotension.
885 studies on the registry are indexed under Hypotension; 195 are open to participants now.
This study's planned enrollment of 99 is close to the median of 90 across 265 observational studies indexed under Hypotension.
Browse Hypotension studies →Ankara City Hospital Bilkent is the lead sponsor of 443 studies on the registry; 111 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The criteria were revised on the registry on Oct 28, 2026. See what changed
Adults aged 18 years or older who are scheduled for elective gastrointestinal tumor surgery under general anesthesia. Eligible participants will be ASA physical status I-III and have a Body mass index (BMI) \<40 kg/m². Both sexes will be eligible.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
The share of blood the heart’s main pumping chamber (the left ventricle) pushes out with each beat, measured by an echocardiogram (heart ultrasound) or a MUGA scan. About 50–70% is normal.
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
LVEF (left ventricular ejection fraction)
The share of blood the heart’s main pumping chamber (the left ventricle) pushes out with each beat, measured by an echocardiogram (heart ultrasound) or a MUGA scan. About 50–70% is normal.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Clinically significant
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients scheduled for elective gastrointestinal tumor surgery under general anesthesia who undergo preoperative carotid Doppler assessment and a passive leg raising (PLR) maneuver
Predictive performance of dynamic changes in carotid Doppler parameters (velocity time integral [VTI], peak systolic velocity [PSV], and corrected flow time [FTc]) for post-induction hypotension
Evaluation of the predictive performance of percentage changes in carotid artery velocity time integral (ΔVTI), peak systolic velocity (ΔPSV), and corrected flow time (ΔFTc) after passive leg raising maneuver for post-induction hypotension
Time frame: From pre-induction passive leg raising assessment to 20 minutes after general anesthesia induction
Association of baseline carotid Doppler parameters with post-induction hypotension
Evaluation of the association between baseline carotid Doppler parameters (velocity time integral \[VTI\], peak systolic velocity \[PSV\], and corrected flow time \[FTc\]) and the development of post-induction hypotension.
Time frame: From pre-induction assessment to 20 minutes after general anesthesia induction
Cut-off values of changes in carotid Doppler parameters for prediction of post-induction hypotension
Determination of the optimal cut-off values of velocity time integral \[VTI\], peak systolic velocity \[PSV\], and corrected flow time \[FTc\] for predicting post-induction hypotension.
Time frame: From pre-induction passive leg raising assessment to 20 minutes after general anesthesia induction
Association of carotid Doppler changes with duration and severity of hypotension
Evaluation of the association between velocity time integral \[VTI\], peak systolic velocity \[PSV\], and corrected flow time \[FTc\] and the duration and severity of post-induction hypotension.
Time frame: From general anesthesia induction to 20 minutes post-induction
Association of carotid Doppler changes with vasopressor requirement
Evaluation of the association between velocity time integral \[VTI\], peak systolic velocity \[PSV\], and corrected flow time \[FTc\] and the requirement for vasopressor treatment after anesthesia induction.
Time frame: From general anesthesia induction to 20 minutes post-induction
Plan to share: No — The data will not be shared to protect patient privacy and confidentiality in accordance with institutional policies and local regulations
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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