Drug
Ondansetron clinical trials
Also written Zofran, Zofran ODT, EUR-1025 and GR 38032F.
- studies test it
- 232
- open now
- 27
- in phase 3
- 37
- first study started
- 1998
Keep track of what changes. Save the Ondansetron studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Zofran
- 63
Development codes
Studies by the year they started
231 studies that test it; most in 2008 (14)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 2000 | 2 |
| 2001 | 3 |
| 2002 | 5 |
| 2003 | 6 |
| 2004 | 5 |
| 2005 | 6 |
| 2006 | 5 |
| 2007 | 8 |
| 2008 | 14 |
| 2009 | 13 |
| 2010 | 8 |
| 2011 | 11 |
| 2012 | 9 |
| 2013 | 8 |
| 2014 | 9 |
| 2015 | 12 |
| 2016 | 8 |
| 2017 | 9 |
| 2018 | 10 |
| 2019 | 8 |
| 2020 | 12 |
| 2021 | 14 |
| 2022 | 8 |
| 2023 | 7 |
| 2024 | 7 |
| 2025 | 10 |
| 2026 | 13 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 5
- Phase 1
- 36
- Phase 2
- 50
- Phase 3
- 37
- Phase 4
- 64
- No phase
- 50
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 38 · Other 194
Tanta University (7) · Assiut University (5) · University of Virginia (5) · University of British Columbia (4) · Stanford University (4) · Merck Sharp & Dohme LLC (4) · GlaxoSmithKline (4) · Par Pharmaceutical, Inc. (4)
Often tested with
Tested in the same studies.
Dexamethasone (33) · Aprepitant (13) · Palonosetron (10) · Metoclopramide (10) · Granisetron (8) · Droperidol (8) · Acetaminophen (5) · Fosaprepitant (4)
Studies
Open first, then newest update. How each study uses Ondansetron is read from its arms, and is right about nine times in ten.
Testing it · 232
- Ondansetron to Prevent Oral Rehydration Failure in Children With CholeraNot yet recruitingPhase 2Public Interest Science CenterNCT07795060Written as Ondansetron
- Effects of Ondansetron Timing During Spinal Anesthesia for Urologic SurgeryNot yet recruitingPhase 4Istanbul UniversityNCT07858149Written as Ondansetron 8 mg
- Routine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal AnesthesiaRecruitingPhase 4Sanliurfa Education and Research HospitalNCT07740577Written as Ondansetron 4mg
- Time to First Rescue Antiemetic With Ondansetron Plus Metoclopramide Versus Dexamethasone Plus Metoclopramide for PONV Prophylaxis in Laparoscopic CholecystectomyRecruitingPhase 4Faisalabad Medical UniversityNCT07638527Written as ondansetron 4 mg
- Sleep Quality - Comparing the Effect of Ondansetron or Dexamethasone Given as Routine Prophylaxis Intraoperatively to Prevent Post Operative Nausea and Vomiting (SCORPION)Not yet recruitingPhase 4Telethon Kids InstituteNCT07777276Written as Ondansetron iv
- The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related ToxicitiesRecruitingPhase 2First Affiliated Hospital of Wenzhou Medical UniversityNCT07381634Written as ondansetron
- Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean SectionRecruitingNot applicableTanta UniversityNCT07511491Written as Ondansetron intravenous
- Ondansetron Versus Lidocaine for Preventing Pain on Propofol Injection.Not yet recruitingNot applicableMongi Slim HospitalNCT07632144Written as Ondansetron 8 mg
- Ondansetron for the Prevention of Patient Self-Inflicted Lung Injury in Patients With ARDS - Pilot RCTNot yet recruitingPhase 2/3Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealNCT07588217Written as Ondansetron hydrochloride 8 mg IV Q8H
- Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and DyspepsiaRecruitingPhase 2Mayo ClinicNCT03865290Written as Ondansetron 8mg
- Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in TonsillectomyRecruitingNot applicableTanta UniversityNCT07489742Written as Ondansetron intravenous
- Evaluating the Safety and Efficacy of Ondansetron in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography PancreatitisRecruitingPhase 3Tanta UniversityNCT06861010Written as Ondansetron
- Post Operative Shivering Following AnesthesiaNot yet recruitingNot applicableSohag UniversityNCT07377903Written as Ondansetron 8 mg
- Ondansetron for the Management of Atrial FibrillationRecruitingPhase 4Indiana UniversityNCT05844501Written as Ondansetron 8mg
- BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to OndansetronRecruitingPhase 4University of Illinois at ChicagoNCT04150614Written as Ondansetron
- Efficacy of Co-Spinal Ondansetron In Inguinal HerniorrhaphyEnrolling by invitationNot applicableSuez Canal UniversityNCT06850740Written as Ondansetron 8mg
- Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia HypotensionEnrolling by invitationNot applicableNada kamel ElgamalNCT06930456Written as ondansetron
- Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean SectionRecruitingPhase 1Wayne State UniversityNCT06297499Written as Ondansetron 8mg
- Preventative Effect of Combining Dexamethasone with Ondansetron on Postoperative Nausea, Vomiting and Shivering in Children Undergoing Caudal Anesthesia on Hypospadias SurgeryNot yet recruitingPhase 4Assiut UniversityNCT06747975Written as Dexamethasone and Ondansetron
- Role of Ondansetron in Spinal Anaesthesia Induced HypotensionNot yet recruitingPhase 2/3Assiut UniversityNCT06727201Written as Ondansetron (Zofran)
See all 232 studies that test Ondansetron →
Given in every arm · 75 — Ondansetron is usual care beside what is tested
- Amisulpride Injection for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic SurgeryNot yet recruitingNot applicableQianfoshan HospitalNCT07891312Written as Ondansetron
- Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy VolunteersRecruitingPhase 4Karuna Therapeutics, Inc., a Bristol Myers Squibb companyNCT07681076Written as Ondansetron
- Aprepitant to Improve Same Day Discharge for TKANot yet recruitingPhase 4Endeavor HealthNCT07639723Written as Ondansetron (Zofran)
- Role of Prophylactic Antiemetics in Women Receiving Intrathecal Morphine and Lipophilic Opioids Added to Bupivacaine for Cesarean SectionNot yet recruitingPhase 4Assiut UniversityNCT06704139Written as Ondansetron + Dexamethasone
- Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal SurgeryRecruitingPhase 3University of SaskatchewanNCT04144933Written as Dexamethasone, Ondansetron
- A Trial to Evaluate Interactions Between Antiemetic Medication and AMG 133 in Participants Living With Overweight or ObesityCompletedPhase 1AmgenNCT07310563Written as Ondansetron
- Multimodal Analgesia Effect on Post Surgical PatientCompletedPhase 4University of California, DavisNCT04240626Written as Zofran Injection
- PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell CancersCompletedPhase 1/2National Cancer Institute (NCI)NCT04209595Written as Ondansetron
- Continuous Infusion of First-Generation 5-HT3 Receptor Antagonists in Combination With DexamethasoneCompletedPhase 3Immune Oncology Research InstituteNCT05872893Written as Ondansetron
- Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated DataCompletedPhase 3Jennifer Holder-MurrayNCT04606264Written as Ondansetron 4 MG
- E7 TCR T Cells for Human Papillomavirus-Associated CancersCompletedPhase 1/2National Cancer Institute (NCI)NCT02858310Written as Ondansetron
- Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)CompletedNot applicableM.D. Anderson Cancer CenterNCT02473042Written as Zofran
- T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial CancersTerminatedPhase 1National Cancer Institute (NCI)NCT05035407Written as Ondansetron
- Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology PatientsTerminatedPhase 3University of Michigan Rogel Cancer CenterNCT04503668Written as Ondansetron
- Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic ChemotherapyCompletedPhase 3Alliance for Clinical Trials in OncologyNCT03578081Written as Ondansetron Hydrochloride
- Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP SurgeryCompletedNot applicableChulalongkorn UniversityNCT06153602Written as Ondansetron 8mg
- A Cohort Study Evaluating the Efficacy of PO Magnesium in the Treatment of Acute Traumatic Brain Injury in AdolescentsCompletedEarly Phase 1Spectrum Health - LakelandNCT03475693Written as Zofran ODT 4 MG Disintegrating Oral Tablet
- Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve GastrectomyCompletedPhase 4Stony Brook UniversityNCT03435003Written as Ondansetron
- Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of PregnancyCompletedPhase 2Women and Infants Hospital of Rhode IslandNCT05098067Written as Ondansetron
- Low Dose Aprepitant for Patients Receiving CarboplatinTerminatedPhase 2Albert Einstein College of MedicineNCT03237611Written as Ondansetron 16 MG
Showing 20 of 75.
As the comparator · 51 — what is tested is compared with Ondansetron
- Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC)RecruitingPhase 2Helsinn Healthcare SANCT06904235Written as Reference Treatment: IV ondansetron infusion
- Inhaled Isopropyl Alcohol for Treatment of NauseaRecruitingPhase 2/3State University of New York at BuffaloNCT05418244Written as Oral Ondansetron
- Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in PreeclampsiaNot yet recruitingPhase 4Assiut UniversityNCT07793760Written as Ondansetron
- Antiemetic Fosaprepitant To Remedy Nausea and VomitingRecruitingPhase 2/3Montefiore Medical CenterNCT06382012Written as Ondansetron 4 mg
- Intravenous Versus Perineural Ondansetron for Laparoscopic Sleeve GastrectomyRecruitingNot applicableTanta UniversityNCT06810882Written as Intravenous ondansetron
- A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HECCompletedPhase 3Heron TherapeuticsNCT02106494Written as Ondansetron
- Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female PatientsActive, not recruitingPhase 1Makassed General HospitalNCT07201883Written as Ondansetron (Zofran)
- Comparison of Haloperidol and Ondansetron in Reducing Postoperative Nausea and Vomiting in RA-SAB PatientsCompletedNot applicableRully RiyandikaNCT07087925Written as Ondansetron 4mg
- A Trial of HRS5580 in Prevention of Postoperative Nausea and Vomiting of AdultsCompletedPhase 2Fujian Shengdi Pharmaceutical Co., Ltd.NCT06475846Written as Ondansetron
- Palonosetron vs Ondansetron In PONV Prophylaxis Among Idiopathic Scoliosis PatientsCompletedPhase 4University of MalayaNCT05956899Written as Ondansetron
- The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other AntiemeticsCompletedPhase 2/3University of BaghdadNCT06390787Written as Ondansetron
- Food Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00648804Written as Zofran ODT® Tablets 8 mg
- Fasting Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00649363Written as Zofran ODT® Tablets 8 mg
- Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC)CompletedPhase 4Dr. Marco L.A. SivilottiNCT03056482Written as Ondansetron 8mg
- Antiemetic Prophylaxis With Fosaprepitant and Ondansetron in Patients Undergoing Thoracic SurgeryStatus unknownNot applicableQilu Hospital of Shandong UniversityNCT05881486Written as Ondansetron 8mg
- Haloperidol for the Treatment of Nausea and Vomiting in the EDCompletedPhase 4Western Michigan University School of MedicineNCT04764344Written as Ondansetron
- Comparison of Postoperative Anti-nausea and Vomiting Effect Between Glycopyrronium and OndansetronStatus unknownPhase 4The Second Affiliated Hospital of Chongqing Medical UniversityNCT05265507Written as Ondansetron
- Postoperative Vomiting in Children - Is Dextrose an Effective Prophylactic Anti-emetic?CompletedNot applicableUniversity of SaskatchewanNCT01912807Written as Ondansetron (Control)
- EMS Use of Isopropyl Alcohol Aromatherapy Versus OndansetronCompletedNot applicableThe University of Texas Health Science Center at San AntonioNCT02618343Written as Ondansetron
- A Study of Aprepitant (MK-0869) in Pediatric Participants Undergoing Surgery (MK-0869-148)CompletedPhase 1Merck Sharp & Dohme LLCNCT00819039Written as Ondansetron
Showing 20 of 51.
Codes
What other systems call Ondansetron · ClinicalTrials.gg INT008573
- MeSH (NLM) D017294OndansetronConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 4AF302ESOSONDANSETRONConfirmed FDA, NLM, Wikidata
- RxNorm 26225Confirmed FDA, Wikidata
- Wikidata Q410011ondansetronConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1119OndansetronOne source FDA
- DrugBank DB00904One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D017294 | Ondansetron | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 4AF302ESOS | ONDANSETRON | Confirmed FDA, NLM, Wikidata |
| RxNorm | 26225 | — | Confirmed FDA, Wikidata |
| Wikidata | Q410011 | ondansetron | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1119 | Ondansetron | One source FDA |
| DrugBank | DB00904 | — | One source Wikidata |
Also registered as ondansetron hydrochloride (UNII NMH84OZK2B · RxNorm 203148).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.