Drug
Propofol clinical trials
Also written Diprivan and Fresofol.
- studies test it
- 644
- open now
- 82
- in phase 3
- 48
- first study started
- 1996
Keep track of what changes. Save the Propofol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
643 studies that test it; most in 2017 (51)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 2000 | 1 |
| 2003 | 6 |
| 2004 | 6 |
| 2005 | 8 |
| 2006 | 13 |
| 2007 | 13 |
| 2008 | 26 |
| 2009 | 24 |
| 2010 | 30 |
| 2011 | 22 |
| 2012 | 28 |
| 2013 | 26 |
| 2014 | 41 |
| 2015 | 46 |
| 2016 | 46 |
| 2017 | 51 |
| 2018 | 21 |
| 2019 | 24 |
| 2020 | 33 |
| 2021 | 21 |
| 2022 | 38 |
| 2023 | 33 |
| 2024 | 34 |
| 2025 | 25 |
| 2026 | 26 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 13
- Phase 1
- 35
- Phase 2
- 39
- Phase 3
- 48
- Phase 4
- 260
- No phase
- 267
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 19 · Other 625
Yonsei University (22) · Ain Shams University (12) · Seoul National University Hospital (12) · Assiut University (11) · Konkuk University Medical Center (8) · University of British Columbia (7) · The University of Hong Kong (6) · Kaohsiung Medical University Chung-Ho Memorial Hospital (6)
Often tested with
Tested in the same studies.
Sevoflurane (134) · Dexmedetomidine (102) · Midazolam (52) · Ketamine (47) · Remifentanil (47) · Desflurane (33) · Fentanyl (31) · Isoflurane (16)
Studies
Open first, then newest update. How each study uses Propofol is read from its arms, and is right about nine times in ten.
Testing it · 644
- Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department.Not yet recruitingPhase 4Sultan Qaboos UniversityNCT07874919Written as propofol
- Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus SurgeryNot yet recruitingPhase 4Assiut UniversityNCT07871292Written as Ketamine and Propofol
- Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress DisorderRecruitingPhase 2Stanford UniversityNCT06577636Written as Propofol
- Brain Activity and Changes in Consciousness During General AnesthesiaNot yet recruitingPhase 4Beijing Chao Yang HospitalNCT07836205Written as Propofol (Group P)
- Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance ImagingRecruitingPhase 4Boston Children's HospitalNCT07369128Written as Propofol (IV) 2-4 mg/kg
- Effects of Remimazolam on Postoperative Cognitive Dysfunction and Neuroinflammatory Biomarkers in Patients Undergoing Aortic Arch SurgeryNot yet recruitingPhase 4Seoul National University HospitalNCT07816068Written as propofol
- Effects of Fospropofol Disodium TIVA and IVIH on Surgical Field Quality in Adult ESSRecruitingNot applicableTongji HospitalNCT07788157Written as Propofol
- Impact of Dexmedetomidine Versus Propofol on Intracranial Pressure in Adult Traumatic Brain Injury Patients: Randomized Controlled Double-Blind TrialNot yet recruitingPhase 4Assiut UniversityNCT07807579Written as Propofol
- Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic RepairNot yet recruitingPhase 4Seoul National University HospitalNCT07806006Written as propofol
- Total Intravenous Anesthesia and Recurrence Free SurvivalRecruitingPhase 3The Cleveland ClinicNCT04513808Written as Propofol-based total intravenous anesthesia
- Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in ChildrenRecruitingPhase 4Pakistan Institute of Medical SciencesNCT07799311Written as propofol 1mg/kg
- Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage IIRecruitingPhase 2Washington University School of MedicineNCT06867549Written as Propofol
- Intraoperative Targeted Versus Liberal Blood Pressure Management in Patients Undergoing Off-pump Coronary Artery Bypass GraftingNot yet recruitingNot applicableChinese Academy of Medical Sciences, Fuwai HospitalNCT07787364Written as Propofol
- Effects Of Propofol And Sevoflurane On Plasma Mirna Levels İn Living Kidney DonorsRecruitingNot applicableUniversity of GaziantepNCT07760402Written as propofol
- Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric GastroscopyNot yet recruitingPhase 4Second Affiliated Hospital of Wenzhou Medical UniversityNCT07748884Written as Fentanyl and Propofol
- Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.Not yet recruitingNot applicableChina-Japan Friendship HospitalNCT07736352Written as Propofol + Remifentanil +Midazolam
- Comparing Sedatives for Intracranial Pressure Control in Traumatic Brain InjuryNot yet recruitingNot applicableAswan UniversityNCT07678216Written as propofol
- Development of a Pharmacodynamic Model for Propofol in Older AdultsRecruitingNot applicablePontificia Universidad Catolica de ChileNCT05790720Written as Propofol
- a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right ShuntsRecruitingPhase 1Ain Shams UniversityNCT07669012Written as Ketamine + propofol
- The Effects of Different Anesthetics on the Brain's Neural NetworksNot yet recruitingPhase 4Fudan UniversityNCT07644663Written as propofol
See all 644 studies that test Propofol →
Given in every arm · 149 — Propofol is usual care beside what is tested
- CoreSys Monitoring for Intraoperative Stress Management in Abdominal HysterectomyRecruitingNot applicableHospital Provincial de RosarioNCT07571473Written as propofol
- A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of KL0011034 Injection Administered by Continuous Infusion in Healthy Adult SubjectsNot yet recruitingPhase 1Hunan Kelun Pharmaceutical Co., Ltd.NCT07828470Written as propofol injectable emulsion
- Arm Elevation for Prevention of Propofol Injection PainNot yet recruitingNot applicableMayo ClinicNCT07785674Written as Propofol
- The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline AnesthesiaNot yet recruitingNot applicableChina-Japan Friendship HospitalNCT07699523Written as Propofol
- Study of Psilocybin Under Anesthesia Controlled by EEGNot yet recruitingPhase 2Stanford UniversityNCT07479550Written as Propofol
- Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity SurgeryRecruitingNot applicableGöteborg UniversityNCT03756961Written as Propofol
- Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose KetamineRecruitingPhase 4Insel Gruppe AG, University Hospital BernNCT06951802Written as Propofol
- Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case SurgeriesEnrolling by invitationEarly Phase 1Zagazig UniversityNCT06561672Written as Propofol
- Effect of Amobarbital Sodium Combined With Low-dose Propofol on Hemodynamics During Induction and Perioperative Adverse ReactionsNot yet recruitingPhase 4Tongji HospitalNCT06385756Written as Propofol
- Intravenous Lidocaine to Reduce ED50 for Propofol Administered Using Target Controlled Infusion (TCI) During GastroscopyRecruitingNot applicableErasme University HospitalNCT06143410Written as Propofol injection
- Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in ColonoscopyNot yet recruitingPhase 2/3Assiut UniversityNCT06131905Written as Propofol
- Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock PatientsRecruitingPhase 3Nanfang Hospital, Southern Medical UniversityNCT05839366Written as Remifentanil + propofol
- The Dose Range of Remimazolam Besylate in Different Age GroupsRecruitingNot applicableTongji HospitalNCT06009991Written as Propofol
- Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA StudyRecruitingPhase 2University of Kansas Medical CenterNCT06017141Written as Propofol
- Minimal Flow Anesthesia and Infection RiskCompletedNot applicableAnkara City Hospital BilkentNCT07092046Written as Propofol 1%
- Combined Pectoserratus and Superficial Cervical Plexus Block Versus Local Infiltration for Chemoport ImplantationCompletedNot applicableIndonesia UniversityNCT07771712Written as Propofol
- Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal HysterectomyCompletedPhase 2KK Women's and Children's HospitalNCT03231683Written as Propofol
- Low-dose Propofol Plus High-dose Alfentanil in Rapid Sequence InductionCompletedNot applicableAoyang Hospital Affiliated to Jiangsu UniversityNCT07730918Written as propofol
- Effect of Subanaesthetic Dose of Ketamine on Depth of Anaesthesia ConsistencyCompletedNot applicableSir Ganga Ram HospitalNCT06986109Written as Propofol
- Interest of Audiovisual Distraction in the Management of Anxiety and Pain During Oocyte RetrievalCompletedNot applicableCMC Ambroise ParéNCT04213781Written as Propofol
Showing 20 of 149.
As the comparator · 270 — what is tested is compared with Propofol
- Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU PatientsNot yet recruitingPhase 3Sun Yat-sen UniversityNCT07880548Written as Propofol group
- Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic CholecystectomyRecruitingPhase 4Universidade Federal de SergipeNCT07717684Written as Propofol
- Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation AblationNot yet recruitingPhase 4Hüseyin Ulaş PinarNCT07877116Written as propofol
- Propofol or Esketamine: Tracheal Intubation ComparisonNot yet recruitingPhase 4Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyNCT07847255Written as Propofol
- Safety, Pharmacokinetics, and Pharmacodynamics of Continuous KL0011034 Infusion in Healthy Chinese AdultsNot yet recruitingPhase 1The Third Xiangya Hospital of Central South UniversityNCT07841626Written as Propofol Injectable Emulsion
- The Use of Remimazolam for TEENot yet recruitingPhase 4Icahn School of Medicine at Mount SinaiNCT07829458Written as Propofol
- The Effect of Ciprofol Versus Propofol Anesthesia on Postoperative Neurological ComplicationsNot yet recruitingNot applicableBeijing Tiantan HospitalNCT07805876Written as Propofol
- Remimazolam for Postoperative Sleep in Elderly PatientsRecruitingNot applicableGeneral Hospital of Ningxia Medical UniversityNCT07740343Written as propofol
- Ciprofol, Propofol and Sevoflurane for Postoperative Delirium in Elderly Brain Tumor PatientsNot yet recruitingNot applicableUnion Hospital, Tongji Medical College, Huazhong University of Science and TechnologyNCT07799623Written as Propofol
- Propofol-Dexmedetomine Adjunction in Balanced Anesthesia for Minimally Invasive Cardiac Valve Surgery :Effect on Anesthetic Consumption ,Perioperative Outcomes,and Early RecoveryNot yet recruitingPhase 1/2Kafrelsheikh UniversityNCT07798089Written as Propofol (Astra-Zeneca)
- Remimazolam Versus Propofol for Maintenance of Anaesthesia During Major Hepatectomy Under Low Central Venous PressureNot yet recruitingPhase 4Beijing Tsinghua Chang Gung HospitalNCT07789275Written as Propofol
- Effects of Remimazolam on Postoperative Myocardial InjuryEnrolling by invitationNot applicableAffiliated Hospital of Jiaxing UniversityNCT07725185Written as Propofol
- Remimazolam Versus Propofol for Early Recovery After Cytoreductive SurgeryNot yet recruitingNot applicableBeijing Tsinghua Chang Gung HospitalNCT07785557Written as Propofol
- Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General AnesthesiaRecruitingPhase 4General Hospital of Ningxia Medical UniversityNCT07670923Written as Propofol Injection
- Ciprofol vs Propofol for Hemodynamic Stability in Patients Having General Anesthesia for Endovascular Thrombectomy After Ischemic StrokeNot yet recruitingPhase 4RenJi HospitalNCT07696208Written as Propofol
- Remimazolam on the Incidence of Postoperative Acute Kidney InjuryNot yet recruitingNot applicableSeoul National University Bundang HospitalNCT07674719Written as propofol
- Inhaled Sedation in Critically Ill PatientsRecruitingPhase 4Instituto de Investigación Hospital Universitario La PazNCT07000526Written as Propofol
- Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day SurgeryNot yet recruitingPhase 4Chung-Ang University Gwangmyeong HospitalNCT07663877Written as propofol
- Propofol vs. Ciprofol for Anesthesia Induction in Frail Elderly PatientsNot yet recruitingNot applicableGeneral Hospital of Ningxia Medical UniversityNCT07663695Written as Propofol
- Volatile Sedation for Patients With the Acute Respiratory Distress SyndromeRecruitingPhase 2/3Guy's and St Thomas' NHS Foundation TrustNCT06014138Written as Propofol
Showing 20 of 270.
Codes
What other systems call Propofol · ClinicalTrials.gg INT008493
- MeSH (NLM) D015742PropofolConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) YI7VU623SFPROPOFOLConfirmed FDA, NLM, Wikidata
- RxNorm 8782Confirmed FDA, Wikidata
- Wikidata Q422740propofolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29384PropofolOne source FDA
- DrugBank DB00818One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015742 | Propofol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | YI7VU623SF | PROPOFOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8782 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422740 | propofol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29384 | Propofol | One source FDA |
| DrugBank | DB00818 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.