Drug
Ephedrine clinical trials
- studies test it
- 52
- open now
- 9
- in phase 3
- 4
- first study started
- 2000
Keep track of what changes. Save the Ephedrine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
52 studies that test it; most in 2023 (8)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2007 | 2 |
| 2009 | 1 |
| 2012 | 7 |
| 2014 | 3 |
| 2015 | 2 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 4 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 3 |
| 2023 | 8 |
| 2024 | 5 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 2
- Phase 2
- 8
- Phase 3
- 4
- Phase 4
- 22
- No phase
- 19
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 52
Ain Shams University (3) · Assiut University (3) · Hopital Charles Nicolle (2) · Beijing Tiantan Hospital (2) · Mongi Slim Hospital (2) · Pennington Biomedical Research Center (2) · Bayside Health (2) · Cairo University (2)
Often tested with
Tested in the same studies.
Phenylephrine (17) · Norepinephrine (14) · Caffeine (4) · Atropine (2) · Epinephrine (2) · Pioglitazone (2) · Ketamine (1) · Ondansetron (1)
Studies
Open first, then newest update. How each study uses Ephedrine is read from its arms, and is right about nine times in ten.
Testing it · 52
- Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean DeliveryRecruitingPhase 4Cairo UniversityNCT07379710Written as Ephedrine and Norepinephrine infusion
- Intermittent Ephedrine Boluses for Prophylaxis Against Postinduction HypotensionRecruitingNot applicableCairo UniversityNCT07722013Written as Ephedrine
- Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSERecruitingPhase 4Icahn School of Medicine at Mount SinaiNCT05873218Written as Ephedrine
- Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro StudyRecruitingNot applicableSamuel Lunenfeld Research Institute, Mount Sinai HospitalNCT06285396Written as Ephedrine
- Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro StudyRecruitingNot applicableSamuel Lunenfeld Research Institute, Mount Sinai HospitalNCT04053478Written as Ephedrine
- Appropriate Dosage of Vasopressor in Neonates and InfantsNot yet recruitingPhase 4Seoul National University HospitalNCT06257316Written as EPHEDrine Hydrochloride 5 mg/ml
- Could Ephedrine Replace Dexmedetomidine Fordexmedetomidine Prevention of Shivering in Women Undergoing Cesarean Section Under Spinal AnaesthesiaRecruitingNot applicableAssiut UniversityNCT06233032Written as Ephedrine
- Cerebral Flow-metabolism Coupling During Adult SurgeryRecruitingPhase 4Jason ChuiNCT05941494Written as Ephedrine
- Effects of Vasopressors on Cerebral Hemodynamics in Patients With Carotid Endarterectomy (MRI Part)Not yet recruitingNot applicableBeijing Tiantan HospitalNCT05414877Written as Ephedrine
- Ephedrine for Reducing Onset Time of Rocurinium in Elderly PatientsCompletedPhase 4Matias VestedNCT06681662Written as Ephedrine Hydrochloride 30 mg/ml
- Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid SurgeryCompletedPhase 4University Hospital, Clermont-FerrandNCT01794273Written as ephedrine and phenylephrine
- Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus EphedrineCompletedNot applicableHopital Charles NicolleNCT06498076Written as Ephedrine
- Management of Post-Induction Hypotension in Emergency Abdominal SurgeryTerminatedPhase 4Hopital Charles NicolleNCT07259655Written as Ephedrine (6 mg boluses)
- Determination of the Optimal Dose of Ephedrine in Intraoperative Arterial Hypotension of Newborns and Infants up to 6 Months of Age.CompletedPhase 2Hospices Civils de LyonNCT02384876Written as Ephedrine 30mg/10mL injectable solution, single administration, dose : 0.6, 0.8, 1.0, 1.2 and 1.4 mg/kG
- Prophylactic Perioperative Infusion of Ephedrine Versus Noradrenaline in Patients Undergoing Cesarean Delivery Under Spinal AnesthesiaCompletedNot applicableTanta UniversityNCT07067944Written as Ephedrine
- Ketamine vs Ephedrine on Post Spinal Hypotension in Caesarean DeliveryCompletedPhase 1Ain Shams UniversityNCT07034911Written as Ephedrine
- HIgh Versus STAndard Blood Pressure Target in Hypertensive High-risk Patients Undergoing Major Abdominal SurgeryCompletedNot applicableHumanitas Clinical and Research CenterNCT05637606Written as Ephedrine
- Effects of Vasopressors on Cerebral Hemodynamics in Patients With Carotid Endarterectomy (TCD Part)CompletedNot applicableBeijing Tiantan HospitalNCT05665881Written as Ephedrine
- Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean SectionCompletedPhase 4B.P. Koirala Institute of Health SciencesNCT06668337Written as Ephedrine
- Intubation Conditions After RSI Using Rocuronium with Ephedrine PretreatmentCompletedPhase 3Ain Shams UniversityNCT05725031Written as Ephedrine
See all 52 studies that test Ephedrine →
Given in every arm · 14 — Ephedrine is usual care beside what is tested
- Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) SystemActive, not recruitingNot applicableKK Women's and Children's HospitalNCT03620942Written as Ephedrine
- A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic StabilityCompletedPhase 2/3KK Women's and Children's HospitalNCT02277730Written as ephedrine
- Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean SectionCompletedPhase 2/3KK Women's and Children's HospitalNCT04025918Written as Ephedrine
- Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.CompletedPhase 2Kasr El Aini HospitalNCT06327399Written as Ephedrine
- Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean DeliveryCompletedNot applicableMansoura UniversityNCT03252496Written as Intravenous Ephedrine
- Decision Support for Intraoperative Low Blood PressureCompletedNot applicableVanderbilt University Medical CenterNCT02726620Written as Ephedrine
- Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic CholecystectomyCompletedPhase 4B.P. Koirala Institute of Health SciencesNCT02327923Written as Ephedrine
- Nefopam vs Tramadol in the Prevention of Post Anaesthetic ShiveringStatus unknownPhase 2Lagos State Health Service CommissionNCT02441673Written as Ephedrine
- Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean DeliveryCompletedNot applicableMansoura UniversityNCT02961842Written as Intravenous Ephedrine
- Effects of Systemic or Adjunct Tramadol Addition to Lidocaine Used for IVRA in Patients Undergoing Hand SurgeryCompletedPhase 3Bagcilar Training and Research HospitalNCT02658721Written as Ephedrine
- Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal AnesthesiaCompletedPhase 4Sira BangNCT02522858Written as Ephedrine
- Continuous Spinal Anesthesia With Hypobaric Bupivacaine to Preserve Hemodynamics in ElderlyStatus unknownNot applicableInstitut Kassab d'OrthopédieNCT02428257Written as ephedrine
- Intrathecal Levobupivacaine With Opioids for Caesarean SectionCompletedPhase 3Baskent UniversityNCT01858090Written as Ephedrine
- Different Approaches to Maternal Hypotension During Cesarean SectionCompletedPhase 4University of ParmaNCT00991627Written as Ephedrine, continuous infusion
As the comparator · 8 — what is tested is compared with Ephedrine
- Ephedrine Versus Norepinephrine and Fetal Acid-Base Status During Cesarean Delivery Under Spinal AnesthesiaCompletedPhase 4mehmet özkılıçNCT06921473Written as Ephedrine
- Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Postoperative Organ DysfunctionCompletedPhase 3Centre Hospitalier Universitaire, AmiensNCT05276596Written as Ephedrine
- The Effect of Low-dose Atropine on Sympathetic Blockade in Spinal Cesarean Section PatientsCompletedPhase 4Abant Izzet Baysal UniversityNCT05892913Written as Ephedrine
- Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related HypotensionStatus unknownPhase 3Brugmann University HospitalNCT05497700Written as Ephedrine
- Phenylephrine in Spinal Anesthesia in Preeclamptic PatientsCompletedNot applicableNorthwestern UniversityNCT00458003Written as Ephedrine
- Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in ParturientsCompletedNot applicableAir Force Military Medical University, ChinaNCT02542748Written as Ephedrine
- Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care During Vertebroplasty and KyphoplastyCompletedNot applicableHallym University Medical CenterNCT02476981Written as ephedrine
- Different Approaches to Maternal Hypotension During Cesarean SectionCompletedPhase 4University of ParmaNCT00991627Written as Ephedrine, continuous infusion
Codes
What other systems call Ephedrine · ClinicalTrials.gg INT007425
- MeSH (NLM) D004809EphedrineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) GN83C131XSEPHEDRINEConfirmed FDA, NLM, Wikidata
- RxNorm 3966Confirmed FDA, Wikidata
- Wikidata Q219626(−)-ephedrineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C472EphedrineOne source FDA
- DrugBank DB01364One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004809 | Ephedrine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | GN83C131XS | EPHEDRINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3966 | — | Confirmed FDA, Wikidata |
| Wikidata | Q219626 | (−)-ephedrine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C472 | Ephedrine | One source FDA |
| DrugBank | DB01364 | — | One source Wikidata |
Also registered as ephedrine hydrochloride (UNII NLJ6390P1Z · RxNorm 91165) and ephedrine sulfate (UNII U6X61U5ZEG · RxNorm 91166).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.