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Epilepsy clinical trials

The registry lists 1,848 studies for Epilepsy across more than 10 countries. 422 are recruiting or about to start. 1,259 of them are mainly about Epilepsy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 12 narrower conditions too, such as Drug Resistant Epilepsy: 2,335 studies, 553 open.

ClinicalTrials.gov finds 2,553 studies for Epilepsy. How that becomes 1,848 here

This page counts the studies the registry files under Epilepsy, and those it files under no condition that list Epilepsythemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,553Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −486Filed under a narrower condition, counted on its own pageDrug Resistant Epilepsy 154 · Epilepsies, Partial 112 · Epilepsies, Myoclonic 58 · Spasms, Infantile 36 · Epilepsy, Temporal Lobe 29 · Lennox Gastaut Syndrome 20 · 6 more
  3. −48List Epilepsy as a condition, but the registry did not file them under itMost often written as “STXBP1 Encephalopathy With Epilepsy” (4), “Epilepsy in Children” (4), and “Photosensitive Epilepsy” (3). The registry filed them under other conditions only, most often Epilepsy, Post-Traumatic (5) and Epileptic Encephalopathy, Early Infantile, 4 (5).
  4. −171Match it another way61 name it in the title, 15 in a keyword, and 95 by a synonym or other text the search reads.
  5. 1,848The count on this page36 of them list Epilepsy in their own words; the registry filed them under no condition.

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Status

Completed
983
Recruiting
285
Status unknown
170
Terminated
139
Not yet recruiting
86
Active, not recruiting
69

Phase

Phase 3
267
Phase 2
210
Phase 1
146
Phase 4
119
Early Phase 1
16

Where

United States
792
France
254
United Kingdom
150
Germany
138
Italy
128
Belgium
110

Who runs them

UCB Pharma (56) · GlaxoSmithKline (54) · Bial - Portela C S.A. (44) · National Institute of Neurological Disorders and Stroke (NINDS) (42) · Hospices Civils de Lyon (27) · Eisai Inc. (26) · NYU Langone Health (24) · Mayo Clinic (21)

What is being tested here

Drugs under test in Epilepsy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Levetiracetam42860
XEN1101345
RAP-219324
Lamotrigine21236
Brivaracetam22134
Valproic Acid2322
Cannabidiol2920
Zonisamide2819
Ketamine225
Methylphenidate204

Drug classes tested here mTOR inhibitors 2 open · SSRIs 1 open · Serotonin receptor agonists 1 open · Calcium channel blockers 1 open · Anxiolytics 22

Coming up

28phase 3 studies under way
147studies finish main data collection within a year10 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 285 Epilepsy studies recruiting now, 113 (40%) set no upper age limit and 149 (52%) stop at 75 or younger. 139 (49%) take children under 18. 6 (2%) are for women only and 2 (1%) for men only; 56 (20%) take healthy volunteers.

Recruiting studies that take each age, of 285
AgeWomenMen
10103 (36%)102 (36%)
18247 (87%)241 (85%)
30227 (80%)223 (78%)
40224 (79%)221 (78%)
50218 (76%)215 (75%)
65191 (67%)188 (66%)
75152 (53%)149 (52%)
85130 (46%)127 (45%)

Across all 1,848 studies, recruiting or not: 55% stop at 75 or younger and 46% at 65; 49% take children; 2% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Epilepsy studies take

Of 85 phase 3 interventional studies under Epilepsy, half reached primary completion within 48 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 18 mo3–22 · 55 studies4 mo1–10 · 34 studies—
Phase 223 mo14–40 · 66 studies21 mo11–29 · 45 studies—
Phase 348 mo29–69 · 85 studies48 mo30–70 · 66 studies—
Phase 425 mo12–35 · 43 studies—26 mo11–37 · 33 studies
Interventional, no phase42 mo19–77 · 358 studies—42 mo19–77 · 337 studies
Observational59 mo24–119 · 230 studies34 mo14–59 · 37 studies62 mo33–179 · 193 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting6

Show 1 more

Results posted1

Stopped1

Newly registered13

Show 8 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,848. Browse all 1,848 → or search them.