Epilepsy clinical trials
The registry lists 1,803 studies for Epilepsy across more than 10 countries. 419 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 921
- Recruiting
- 277
- Status unknown
- 199
- Terminated
- 126
- Not yet recruiting
- 88
- Active, not recruiting
- 65
Phase
- Phase 3
- 239
- Phase 2
- 210
- Phase 1
- 132
- Phase 4
- 126
- Early Phase 1
- 22
Where
- United States
- 730
- France
- 247
- Germany
- 140
- United Kingdom
- 131
- Italy
- 119
- China
- 115
Who runs them
UCB Pharma (57) · GlaxoSmithKline (44) · Bial - Portela C S.A. (43) · National Institute of Neurological Disorders and Stroke (NINDS) (39) · Hospices Civils de Lyon (30) · NYU Langone Health (23) · Assistance Publique Hopitaux De Marseille (20) · Eisai Inc. (20)
Studies
Recruiting first, then most recently updated. Showing 50 of 1,803 — search for more.
- Modulating Movement Intention Via Cortical StimulationRecruitingNCT03233399Not applicable1 country
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1RecruitingNCT07563881Phase 32 countries
- Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT000605411 country
- Intracranial CArtography of Cortical Contribution to Respiratory Load Compensation in EpilepsyRecruitingNCT07599150Not applicable1 country
- Time-Domain Heart Rate Variability and QT Interval in Children With EpilepsyNot yet recruitingNCT07834983
- Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant EpilepsyRecruitingNCT02531880Phase 11 country
- Investigating Epilepsy: Screening and EvaluationRecruitingNCT034788521 country
- The Effect of a Kolcaba's Comfort Theory-Based Educational Intervention on the Quality of Life of Patients With EpilepsyNot yet recruitingNCT07827248Not applicable1 country
- Cognitive Rehabilitation Using Neurofeedback With Brain-computer InterfaceRecruitingNCT07828496Not applicable1 country
- Neuronal Mechanisms of Human Episodic MemoryEnrolling by invitationNCT04500119Not applicable1 country
- Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging DatabaseRecruitingNCT021079891 country
- Translational Recording and Characterization of Epilepsy Signals Using Subgaleal EEG During Standard-of-care SEEG MonitoringNot yet recruitingNCT07821697Early Phase 11 country
- Neural Mechanisms of Social Attribution From FacesEnrolling by invitationNCT07822178Not applicable1 country
- A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant EpilepsyRecruitingNCT06388707Phase 1/21 country
- Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset SeizuresNot yet recruitingNCT06534502Phase 41 country
- A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)Enrolling by invitationNCT06908226Phase 315 countries
- Diagnosing Epilepsy To EffeCT ChangeRecruitingNCT07110337Not applicable1 country
- Neuronal Mechanisms of Learning and Utilizing Abstract RepresentationsEnrolling by invitationNCT07454785Not applicable1 country
- Diagnosing Epilepsy To EffeCT Change Long-Term Follow-UpRecruitingNCT071104541 country
- Prospective Natural History Study of POLG DiseaseRecruitingNCT077758729 countries
- Neurofeedback Using Implanted Deep Brain Stimulation ElectrodesRecruitingNCT05101161Not applicable1 country
- SeizEAR Safety StudyRecruitingNCT07088835Not applicable1 country
- A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to EpidiolexNot yet recruitingNCT06924827Phase 41 country
- An Open-label Study of XEN1101 in EpilepsyEnrolling by invitationNCT05718817Phase 325 countries
- HOBSCOTCH-YOUTH and Young AdultsNot yet recruitingNCT07735715Not applicable1 country
- Health Literacy ProjectNot yet recruitingNCT06634901Not applicable1 country
- High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 YearsNot yet recruitingNCT07803692Not applicable1 country
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal SeizuresRecruitingNCT07594119Phase 31 country
- Study of the Intracerebral Electrophysiological Signature in the Epileptic PatientNot yet recruitingNCT077969841 country
- Surgery as a Treatment for Medically Intractable EpilepsyRecruitingNCT012731291 country
- EASEE® System Pivotal Study for the United States of AmericaNot yet recruitingNCT07301346Not applicable1 country
- Tumor Related EpilepsyRecruitingNCT026393251 country
- Lily's Grace Temporal InterferenceNot yet recruitingNCT07520955Not applicable1 country
- Study of Direct Brain Recording and Stimulation for Memory EnhancementEnrolling by invitationNCT040950261 country
- Epileptiform Potential of Fully Immersive Virtual RealityNot yet recruitingNCT07451093Not applicable1 country
- Multi-Parameter Temporal Interference Stimulation in Patients With Epilepsy Undergoing SEEG MonitoringNot yet recruitingNCT07790224Not applicable1 country
- Physiological Brain Atlas DevelopmentRecruitingNCT005750811 country
- AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe EpilepsyRecruitingNCT06063850Phase 1/21 country
- A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset EpilepsyRecruitingNCT06132893Phase 2/314 countries
- Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care PathwaysEnrolling by invitationNCT077759761 country
- Causal Role of Top-Down Theta Oscillations in PrioritizationEnrolling by invitationNCT06252532Not applicable1 country
- Electrophysiologic Mechanisms of Ketamine Antidepressant ResponseNot yet recruitingNCT07768618Phase 21 country
- Brain Development Research ProgramRecruitingNCT003053051 country
- LIFUS For Neurological DisordersRecruitingNCT07417280Not applicable1 country
- Metabolites in Blood and Breath in Metabolic ConditionsNot yet recruitingNCT07704606
- Acute Stimulation and Modulation of Stereotyped High-Frequency OscillationsNot yet recruitingNCT06898138Not applicable1 country
- Impact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory ReactivityNot yet recruitingNCT07249034Not applicable1 country
- A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic SeizuresRecruitingNCT05667142Phase 320 countries
- Subcortical Arousal in Perceptual AwarenessRecruitingNCT06934356Not applicable1 country
- Neuronal and Network Mechanisms of Electrocortical StimulationEnrolling by invitationNCT06391294Not applicable1 country