Epilepsies, Partial clinical trials
The registry lists 243 studies for Epilepsies, Partial across more than 10 countries. 49 are recruiting or about to start. 186 of them are mainly about Epilepsies, Partial (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 2 narrower conditions too, such as Epilepsy, Temporal Lobe: 323 studies, 73 open.
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Status
Who runs them
UCB Pharma (17) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (15) · SK Life Science, Inc. (13) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (12) · National Institute of Neurological Disorders and Stroke (NINDS) (11) · Pfizer (8) · GlaxoSmithKline (7) · Bial - Portela C S.A. (7)
What is being tested here
Drugs under test in Epilepsies, Partial studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| RAP-219 | 3 | 2 | 4 |
| SPN-817 | 2 | 0 | 2 |
| Cenobamate | 1 | 2 | 6 |
| Lamotrigine | 1 | 3 | 6 |
| Opakalim | 1 | 2 | 3 |
| XEN1101 | 1 | 1 | 2 |
| Zonisamide | 1 | 0 | 2 |
| Probenecid | 1 | 0 | 1 |
| CB03-154 | 1 | 0 | 1 |
| Butylphthalide | 1 | 0 | 1 |
Drug classes tested here Anxiolytics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy · Phase 3 · Biohaven Therapeutics Ltd.
- Jan 2027Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures · Phase 3 · Praxis Precision Medicines
- Dec 2026Long-term Safety and Tolerability of BHV-7000 · Biohaven Therapeutics Ltd.
- Dec 2026Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies · Fondation Ophtalmologique Adolphe de Rothschild
- Dec 2026Study of Transcranial Direct Current Stimulation to Treat Epilepsy · Mayo Clinic
- Dec 2026Sleep Architecture & Cognition in Focal Epilepsy · University of California, Davis
- Dec 2026Transcranial Direct Current to Treat Epilepsy at Home · Stanford University
- Dec 2026Prospective Study of Eslicarbazepine in Adults With Focal-Onset Seizures · King Edward Medical University
- Jan 2027Safety of Cenobamate in Japanese Subjects With Partial Onset Seizures · Ono Pharmaceutical Co. Ltd
- Feb 2027RNS System for Drug-Resistant Focal Epilepsy in Adolescents: A Real-World Study · NeuroPace
Who these studies take
Of the 37 Epilepsies, Partial studies recruiting now, 9 (24%) set no upper age limit and 24 (65%) stop at 75 or younger. 17 (46%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (41%) | 15 (41%) |
| 18 | 32 (86%) | 32 (86%) |
| 30 | 28 (76%) | 28 (76%) |
| 40 | 28 (76%) | 28 (76%) |
| 50 | 27 (73%) | 27 (73%) |
| 65 | 24 (65%) | 24 (65%) |
| 75 | 16 (43%) | 16 (43%) |
| 85 | 12 (32%) | 12 (32%) |
Across all 243 studies, recruiting or not: 55% stop at 75 or younger and 41% at 65; 46% take children; <1% are for women only and 1% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 12, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 243. Browse all 243 → or search them.
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1RecruitingNCT07563881Phase 34 countries
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal SeizuresRecruitingNCT07594119Phase 32 countries
- Electrophysiological Dose-Response to Anterior Thalamic Deep Brain Stimulation in Drug-Resistant Focal EpilepsyNot yet recruitingNCT07912931Not applicable1 country
- An Open-label Study of XEN1101 in EpilepsyEnrolling by invitationNCT05718817Phase 325 countries
- SPN-817 Open-Label Extension Study in Adults With Focal Onset SeizuresEnrolling by invitationNCT07141329Phase 22 countries
- Investigating Epilepsy: Screening and EvaluationRecruitingNCT034788521 country
- Surgery as a Treatment for Medically Intractable EpilepsyRecruitingNCT012731291 country
- A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With POS 2 to 17 Year OldsRecruitingNCT07594158Phase 31 country
- Efficacy of Probenecid on Cluster Seizures During Anti Seizure Medication Withdrawal in Presurgical Focal Epilepsy Video-EEG MonitoringRecruitingNCT07318870Phase 21 country
- RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset SeizuresRecruitingNCT06798896Phase 25 countries
- Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic PatientsRecruitingNCT04653012Not applicable1 country
- Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and WearablesRecruitingNCT07012148Early Phase 11 country
- Prospective Study of Postictal Psychotic Symptoms Occuring After Video-EEG Monitoring in Focal EpilepsiesNot yet recruitingNCT07471334Not applicable
- A Study to Evaluate the Safety, Tolerability, and Efficacy of CB03-154 in Adult Patients With Focal EpilepsyRecruitingNCT06612775Phase 21 country
- RNS System for Drug-Resistant Focal Epilepsy in Adolescents: A Real-World StudyEnrolling by invitationNCT078234651 country
- Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset SeizuresNot yet recruitingNCT06534502Phase 41 country
- Prospective Study of Eslicarbazepine in Adults With Focal-Onset SeizuresRecruitingNCT077933961 country
- High-density Flexible μECoG for Epilepsy Surgery - A Single-Arm ECTRecruitingNCT07656857Not applicable1 country
- Sleep Architecture & Cognition in Focal EpilepsyRecruitingNCT05794295Not applicable1 country
- Prognosis of Epilepsy With Post-traumatic Stress Disorder and SurgeryNot yet recruitingNCT07718542
- Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant EpilepsyRecruitingNCT07680842Not applicable1 country
- Spatial Scene Recognition Memory in Epilepsy SurgeryRecruitingNCT07580183Not applicable1 country
- Long-term Safety and Tolerability of BHV-7000Enrolling by invitationNCT06443463Phase 227 countries
- Changes in Attentional Control After a Focal Seizure.RecruitingNCT064666811 country
- Genetic and Electrophysiologic Study in Focal Drug-resistant EpilepsiesRecruitingNCT028906411 country
- High-resolution Multi-parametric Magnetic Resonance Imaging for Focal EpilepsyRecruitingNCT06550726Not applicable1 country
- Thalamic Recordings in Children Undergoing SEEGRecruitingNCT06453759Not applicable1 country
- Study of Transcranial Direct Current Stimulation to Treat EpilepsyRecruitingNCT05673915Not applicable1 country
- A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset SeizuresRecruitingNCT07219407Phase 21 country
- Impact of Epileptic Discharge on the Structural Connectivity of the Developing BrainRecruitingNCT032688241 country
- Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid )RecruitingNCT06205160Not applicable1 country
- An Open-label Study to Evaluate Safety, Tolerability, and Efficacy of CB03-154 in Subjects Diagnosed With EpilepsyRecruitingNCT07238868Phase 21 country
- Butylphthalide for Cognitive Impairment in Elderly Patients With Focal EpilepsyRecruitingNCT07193277Phase 41 country
- Electroclinical Correlation of AnxietyRecruitingNCT05393518Not applicable1 country
- Breathing Rescue for SUDEP PreventionRecruitingNCT05981755Not applicable1 country
- Safety of Cenobamate in Japanese Subjects With Partial Onset SeizuresRecruitingNCT06590896Phase 21 country
- A Clinical Study on the Efficacy and Safety of Zonisamide as a First Add-On Treatment in Epileptic SeizuresRecruitingNCT06967012Phase 41 country
- Mapping Epileptic Networks Using Multimodal ImagingRecruitingNCT062029761 country
- Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic EncephalopathiesRecruitingNCT06855901Not applicable1 country
- Extreme Capsule Electrical Stimulation for Drug-resistant Focal EpilepsyNot yet recruitingNCT06663124Not applicable1 country
- Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy SurgeryRecruitingNCT04986683Not applicable1 country
- Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic EpilepsyRecruitingNCT062100221 country
- Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal EpilepsyRecruitingNCT051007711 country
- Treating Postictal Symptoms Using Ibuprofen and NifedipineRecruitingNCT03949478Phase 21 country
- Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal EpilepsyNot yet recruitingNCT063749661 country
- Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular ElectrodesNot yet recruitingNCT063660091 country
- Atlas of Human Cognition by SEEG (MAPCOG-SEEG)RecruitingNCT036447321 country
- The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal EpilepsyEnrolling by invitationNCT05748236Phase 41 country
- Induced Pluripotent Stem Cell Derived Exosomes Nasal Drops for the Treatment of Refractory Focal EpilepsyRecruitingNCT05886205Early Phase 11 country
- A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal EpilepsyActive, not recruitingNCT03796962Phase 29 countries