Epilepsy, Generalized clinical trials
The registry lists 39 studies for Epilepsy, Generalized across more than 10 countries. 4 are recruiting or about to start. 17 of them are mainly about Epilepsy, Generalized (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28. Counting its 5 narrower conditions too, such as Epilepsies, Myoclonic: 239 studies, 38 open.
Get an email when these change. Save the Epilepsy, Generalized studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
UCB Pharma (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · Lundbeck LLC (2) · Oslo University Hospital (1) · Oregon Health and Science University (1) · Arak University of Medical Sciences (1) · UCB Pharma SA (1) · Second Affiliated Hospital, School of Medicine, Zhejiang University (1)
What is being tested here
Drugs under test in Epilepsy, Generalized studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cenobamate | 1 | 1 | 1 |
| Levetiracetam | 0 | 4 | 4 |
| Topiramate | 0 | 2 | 3 |
| Clobazam | 0 | 1 | 2 |
| NPT 2042 | 0 | 0 | 1 |
| Melatonin | 0 | 0 | 1 |
| Diazepam | 0 | 1 | 1 |
| Opakalim | 0 | 1 | 1 |
Drug classes tested here Anxiolytics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Jan 2027ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures. · Phase 3 · Ono Pharmaceutical Co. Ltd
- May 2027Baker Gordon Syndrome Natural History Study · University of Missouri-Columbia
- Jun 2027Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy · University of California, San Francisco
Who these studies take
Of the 3 Epilepsy, Generalized studies recruiting now, 1 (33%) set no upper age limit and 1 (33%) stop at 75 or younger. 2 (67%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (33%) | 1 (33%) |
| 18 | 2 (67%) | 2 (67%) |
| 30 | 3 (100%) | 3 (100%) |
| 40 | 3 (100%) | 3 (100%) |
| 50 | 3 (100%) | 3 (100%) |
| 65 | 3 (100%) | 3 (100%) |
| 75 | 2 (67%) | 2 (67%) |
| 85 | 2 (67%) | 2 (67%) |
Across all 39 studies, recruiting or not: 46% stop at 75 or younger and 38% at 65; 67% take children; 0% are for women only and 0% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 39 of 39. search them.
- High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 YearsNot yet recruitingNCT07803692Not applicable1 country
- Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant EpilepsyRecruitingNCT07680842Not applicable1 country
- Baker Gordon Syndrome Natural History StudyRecruitingNCT063999521 country
- ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.RecruitingNCT06579573Phase 31 country
- A Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence SeizuresCompletedNCT06769659Phase 21 country
- Comparing the Outcome of Buccal Midazolam and Intramuscular Midazolam in Children Presenting With Seizures.CompletedNCT07626255Phase 41 country
- The Effect of Mandala Coloring on the Quality of Life in Epilepsy Patients: A Single Blind Randomized Controlled StudyCompletedNCT07540013Not applicable1 country
- A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic SeizuresTerminatedNCT06425159Phase 2/314 countries
- Exercise for Memory Rehabilitation in EpilepsyCompletedNCT04959019Not applicable1 country
- Epileptic Psychoses and Their Link With Ictal Emotions and ConsciousnessCompletedNCT069608111 country
- Severity: Quantifying the Severity of Generalized Tonic-clonic Seizures (GTCS) with Connected DevicesCompletedNCT054771211 country
- Assessment of Multifocal Continuous Theta Burst Transcranial Magnetic Stimulation (cTBS) Effects in Generalized Epilepsy Patients.CompletedNCT06797791Not applicable1 country
- Evaluation of the 24/7 EEG™ SubQ System in Subjects With Uncontrolled Genetic Generalised Epilepsy SyndromeCompletedNCT052416781 country
- Helicobacter Pylori Eradication Therapy for Epileptic ChildrenCompletedNCT05297695Phase 2/31 country
- Clinic to Community© Program for Adults With Epilepsy Admitted to Emergency DepartmentsCompletedNCT04248920Not applicable1 country
- Long-term Cardiac Monitoring in EpilepsyTerminatedNCT03955432Not applicable1 country
- Detecting Absence Seizures Using Eye TrackingCompletedNCT044396561 country
- Cognitive Impairments in Children With EpilepsyCompletedNCT050977421 country
- Clinical Features and Outcome of Wilson's Disease With Generalized Epilepsy in Chinese PatientsCompletedNCT049655711 country
- Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized EpilepsyCompletedNCT03590197Phase 41 country
- Post-market Study of AMPA Receptor Antagonists for Epilepsy Patients in Hong KongStatus unknownNCT034579611 country
- Long Term Follow up Treatment With Levetiracetam in Subjects of 4 Years and Older With Generalized EpilepsyCompletedNCT00150748Phase 3
- Transcranial Direct Current Stimulation (tDCS) in Children and Adolescents With Epilepsy and DepressionWithdrawnNCT03368469Not applicable1 country
- Periodic Limb Movement and Genetic Generalized EpilepsyCompletedNCT03587506
- Modified Atkins Diet Treatment for Adults With Drug-resistant EpilepsyCompletedNCT01311440Not applicable1 country
- A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic SeizuresCompletedNCT01393743Phase 3
- Impact of Early Lactate Dosage Compared to CK for Diagnosis of a Suspected SeizureStatus unknownNCT031637191 country
- Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.CompletedNCT00319501Phase 31 country
- Monotherapy With Levetiracetam in Newly Diagnosed Patients Suffering From EpilepsyCompletedNCT00150735Phase 3
- Study to Evaluate the Safety and Efficacy of Levetiracetam in Patients Suffering From Idiopathic Generalized Epilepsy With Primary Generalized Tonic-clonic SeizuresCompletedNCT00160550Phase 3
- Levetiracetam as add-on Treatment of Myoclonic Jerks in Adolescents + AdultsCompletedNCT00150774Phase 3
- Study on Serum Zinc and Selenium Levels in Epileptic PatientsCompletedNCT017645161 country
- Putting Electroencephalography (EEG) in the Emergency DepartmentCompletedNCT013552111 country
- Clobazam in Subjects With Lennox-Gastaut SyndromeCompletedNCT00162981Phase 21 country
- Clobazam in Patients With Lennox-Gastaut SyndromeCompletedNCT00518713Phase 35 countries
- A Study to Evaluate the Dosing, Effectiveness and Safety of Topiramate for the Treatment of EpilepsyCompletedNCT00266604Phase 4
- A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent EpilepsyCompletedNCT00231556Phase 3
- Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy PatientsCompletedNCT00236886Phase 3
- Metabolic Abnormalities in Children With EpilepsyCompletedNCT000013251 country