Drug
Lamotrigine clinical trials
Also written Lamictal.
- studies test it
- 139
- open now
- 3
- in phase 3
- 38
- first study started
- 1993
Keep track of what changes. Save the Lamotrigine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
137 studies that test it; most in 2002 (13)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1995 | 1 |
| 1997 | 1 |
| 2000 | 3 |
| 2002 | 13 |
| 2003 | 12 |
| 2004 | 12 |
| 2005 | 8 |
| 2006 | 11 |
| 2007 | 10 |
| 2008 | 9 |
| 2009 | 3 |
| 2010 | 6 |
| 2011 | 6 |
| 2012 | 7 |
| 2013 | 3 |
| 2014 | 4 |
| 2015 | 5 |
| 2016 | 2 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 4 |
| 2020 | 4 |
| 2021 | 3 |
| 2022 | 3 |
| 2023 | 1 |
| 2024 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 40
- Phase 2
- 20
- Phase 3
- 38
- Phase 4
- 31
- No phase
- 13
What it is tested for
Each study’s main condition, where its own words name it.
- Epilepsy
- 29
Who runs them
Industry 62 · Other 77
GlaxoSmithKline (34) · Dr. Reddy's Laboratories Limited (8) · Teva Pharmaceuticals USA (4) · University of Texas Southwestern Medical Center (3) · University Hospitals Cleveland Medical Center (3) · Mylan Pharmaceuticals Inc (2) · Dent Neuroscience Research Center (2) · University of Maryland, Baltimore (2)
Often tested with
Tested in the same studies.
Valproic Acid (10) · Levetiracetam (8) · Lithium (6) · Carbamazepine (5) · Zonisamide (4) · Oxcarbazepine (4) · Topiramate (4) · Fluoxetine (4)
Studies
Open first, then newest update. How each study uses Lamotrigine is read from its arms, and is right about nine times in ten.
Testing it · 139
- Effect of Adding Lamotrigine to Sodium Valproate in Childhood Epilepsy: Clinicolabratory StudyNot yet recruitingPhase 4Assiut UniversityNCT05881928Written as Lamotrigine
- The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal EpilepsyEnrolling by invitationPhase 4Dhaka Medical CollegeNCT05748236Written as Lamotrigine tablet
- Modification of Epilepsy Screen Questionnaire and Treatment Feasibility EvaluationNot yet recruitingNot applicableNational Taiwan University HospitalNCT04939675Written as LamoTRIgine 50mg
- A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed EpisodeCompletedPhase 4Otsuka Pharmaceutical Development & Commercialization, Inc.NCT00277212Written as Lamotrigine + Aripiprazole
- A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy ParticipantsCompletedPhase 1Karuna Therapeutics, Inc., a Bristol Myers Squibb companyNCT06729970Written as Lamotrigine
- Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW)CompletedPhase 4Mario Negri Institute for Pharmacological ResearchNCT03689114Written as Low dose lamotrigine
- Enhancing the Effects of Alcohol Treatment With LamotrigineCompletedPhase 2Brown UniversityNCT04770493Written as Lamotrigine
- Bioequivalence Study of 200 mg Lamotrigine Tablet Under Non-Fasting ConditionsCompletedPhase 1Teva Pharmaceuticals USANCT00835263Written as Lamotrigine
- Lamotrigine 25 mg Chewable Tablets, Non-FastingCompletedPhase 1Teva Pharmaceuticals USANCT00838136Written as Lamotrigine 25 mg Chewable Tablets
- Lamotrigine 25 mg Chewable Tablets, FastingCompletedPhase 1Teva Pharmaceuticals USANCT00838279Written as Lamotrigine 25 mg Chewable Tablets
- Bioequivalence Study of 200 mg Lamotrigine Tablet Under Fasting ConditionsCompletedPhase 1Teva Pharmaceuticals USANCT00834561Written as Lamotrigine
- Fasting Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00650208Written as Lamotrigine Tablets 25 mg
- Food Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mgCompletedPhase 1Mylan Pharmaceuticals IncNCT00647751Written as Lamotrigine Tablets 25 mg
- A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by KetamineCompletedPhase 1Boehringer IngelheimNCT04602221Written as Lamotrigine
- Single-dose, Two-way Crossover Bioequivalence of Lamotrigine in Healthy Male Volunteers Under Fasting ConditionsCompletedPhase 1Desitin Arzneimittel GmbHNCT06199791Written as Lamotrigine 100 MG
- Synaptic Plasticity and Cognitive Function in RASopathiesTerminatedPhase 2Technical University of MunichNCT03504501Written as Lamotrigine
- Double-Blind Lamictal (Lamotrigine) in Neurotic ExcoriationCompletedPhase 2University of ChicagoNCT00513019Written as Lamictal (lamotrigine)
- Treatment of Myotonia - Lamotrigine Versus NamusclaStatus unknownNot applicableGrete Andersen, MDNCT05639257Written as Lamotrigine
- MExiletine Versus Lamotrigine in Non-Dystrophic MyotoniasStatus unknownPhase 3University College, LondonNCT05017155Written as Lamotrigine 25Mg Oral Tablet, Extended Release
- Bioequivalence of Lamnet (Lamotrigine)100mg Tablet With the Reference Product Lamictal 100mg (Lamotrigine) Tablet Under Fasting ConditionsCompletedPhase 1University of KarachiNCT04938856Written as Lamotrigine tablet
See all 139 studies that test Lamotrigine →
Given in every arm · 6 — Lamotrigine is usual care beside what is tested
- A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)RecruitingPhase 3Bristol-Myers SquibbNCT06929273Written as Lamotrigine
- The Sustained Effects of KetamineTerminatedPhase 1Yale UniversityNCT02708849Written as Lamotrigine
- A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on PadsevonilCompletedPhase 1UCB Biopharma S.P.R.L.NCT03695094Written as Lamotrigine
- Safety and Efficacy Study of ELND005 as an Adjunctive Maintenance Treatment in Bipolar I DisorderTerminatedPhase 2OPKO Health, Inc.NCT01674010Written as Lamotrigine
- Research Study for Major Depressive Disorder: Investigation of Glutamate MedicationsCompletedPhase 4Baylor College of MedicineNCT00419003Written as Lamotrigine
- Maintenance Treatment of Bipolar DepressionCompletedPhase 4The University of Texas Health Science Center at San AntonioNCT00183469Written as Lamotrigine
As the comparator · 5 — what is tested is compared with Lamotrigine
- Lithium Versus Lamotrigine in Bipolar Disorder, Type IIRecruitingPhase 4University Hospital Bispebjerg and FrederiksbergNCT06184581Written as Lamotrigine
- The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy ChildrenStatus unknownPhase 4Dr Cipto Mangunkusumo General HospitalNCT05697614Written as Lamotrigine
- Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial EpilepsyCompletedPhase 3Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00280059Written as Lamotrigine
- Inositol Hexaphosphate: A Novel Treatment Strategy for Bipolar Disorder?CompletedPhase 1San Diego Veterans Healthcare SystemNCT02081287Written as Lamotrigine
- Effect of Antidepressants on the Treatment for Korean Major Depressive Disorder PatientsTerminatedPhase 4Ministry of Health & Welfare, KoreaNCT00926835Written as Paroxetine+Lamotrigine
Codes
What other systems call Lamotrigine · ClinicalTrials.gg INT006668
- MeSH (NLM) D000077213LamotrigineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) U3H27498KSLAMOTRIGINEConfirmed FDA, NLM, Wikidata
- RxNorm 28439Confirmed FDA, Wikidata
- Wikidata Q410346lamotrigineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C38703LamotrigineOne source FDA
- DrugBank DB00555One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077213 | Lamotrigine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | U3H27498KS | LAMOTRIGINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 28439 | — | Confirmed FDA, Wikidata |
| Wikidata | Q410346 | lamotrigine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C38703 | Lamotrigine | One source FDA |
| DrugBank | DB00555 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.