Drug class
Selective Serotonin Reuptake Inhibitors clinical trials
A class of medicines: the studies that test any of its 14 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the selective serotonin reuptake inhibitors studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
Studies by the year they started
1,340 studies that test it; most in 2008 (87); 1 more planned to start later
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1992 | 2 |
| 1994 | 2 |
| 1995 | 3 |
| 1996 | 3 |
| 1997 | 10 |
| 1998 | 11 |
| 1999 | 10 |
| 2000 | 22 |
| 2001 | 37 |
| 2002 | 49 |
| 2003 | 65 |
| 2004 | 66 |
| 2005 | 76 |
| 2006 | 68 |
| 2007 | 49 |
| 2008 | 87 |
| 2009 | 60 |
| 2010 | 70 |
| 2011 | 50 |
| 2012 | 55 |
| 2013 | 42 |
| 2014 | 48 |
| 2015 | 39 |
| 2016 | 51 |
| 2017 | 42 |
| 2018 | 33 |
| 2019 | 46 |
| 2020 | 43 |
| 2021 | 39 |
| 2022 | 43 |
| 2023 | 22 |
| 2024 | 36 |
| 2025 | 34 |
| 2026 | 26 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
- Depression
- 188
- Nausea
- 17
Who runs them
Industry 365 · Other 1,001
Eli Lilly and Company (51) · H. Lundbeck A/S (41) · New York State Psychiatric Institute (36) · Massachusetts General Hospital (25) · Takeda (25) · GlaxoSmithKline (23) · Duke University (19) · University of Pittsburgh (18)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 1,366
- Study of Neuro-Cognitive Correlates of Pediatric Anxiety DisordersRecruitingPhase 2National Institute of Mental Health (NIMH)NCT00018057Written as Fluoxetine
- Psychopharmacotherapy for Depressive PatientsRecruitingNot applicableChonnam National University HospitalNCT06054321Written as stepwise pharmacotherapy
- A Phase 3 Study of Fenfluramine Hydrochloride in Rett SyndromeRecruitingPhase 3UCB BIOSCIENCES, Inc.NCT07503444Written as fenfluramine hydrochloride
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingPhase 4VA Office of Research and DevelopmentNCT07210606Written as Trazodone + positive airway pressure (PAP) therapy
- 7T Amygdala and Citalopram StudyRecruitingNot applicableUniversity of OxfordNCT06412315Written as Citalopram
- Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)RecruitingPhase 2Centre Hospitalier St AnneNCT07210112Written as Trazodone 5mg
- Home Transcutaneous Electrical Acustimulation (TEA)RecruitingPhase 2/3University of MichiganNCT05519683Written as Lexapro
- A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingPhase 4University of PennsylvaniaNCT07542756Written as Trazodone, 50 mg
- Neuroregulators for the Treatment of Diseases Associated With Esophageal-brain-gut Axis Communication Abnormalities.RecruitingNot applicableHualien Tzu Chi General HospitalNCT06778824Written as Zoloft 50Mg Tablet
- Escitalopram and Language Intervention for Subacute AphasiaRecruitingPhase 2Johns Hopkins UniversityNCT03843463Written as Escitalopram 10mg
- Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder FeaturesNot yet recruitingPhase 2Zhifeng Zhao, PhDNCT06506136Written as Fluoxetine
- A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive DisorderRecruitingPhase 3TakedaNCT07204314Written as Vortioxetine tablets
- GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric CancerNot yet recruitingPhase 2University of Illinois at ChicagoNCT07581405Written as Olanzapine
- Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal CancerRecruitingPhase 1Jonsson Comprehensive Cancer CenterNCT06225011Written as Fluoxetine
- Efficacy and Mechanisms of Escitalopram in Drug-Naïve First-Episode Major Depressive DisorderRecruitingNot applicablePeking UniversityNCT07480525Written as Escitalopram (Oral antidepressant)
- Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO TrialRecruitingPhase 2Roswell Park Cancer InstituteNCT06995508Written as Olanzapine
- Long-term Safety Extension Study of OLZ/SAM in Pediatric SubjectsEnrolling by invitationPhase 3Alkermes, Inc.NCT04987229Written as OLZ/SAM
- Antidepressant Therapy for Improved Blood Vessel Health After PreeclampsiaRecruitingEarly Phase 1Anna Stanhewicz, PhDNCT07715669Written as Paroxetine Hydrochloride
- Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic MedicationsRecruitingPhase 3Minerva NeurosciencesNCT07565428Written as olanzapine
- Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental DisordersRecruitingPhase 2Holland Bloorview Kids Rehabilitation HospitalNCT06081348Written as Sertraline
See all 1,366 studies that test one of the selective serotonin reuptake inhibitors →
Codes
What other systems call Selective Serotonin Reuptake Inhibitors · ClinicalTrials.gg INT008597
- MeSH (NLM) D017367Selective Serotonin Reuptake InhibitorsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D017367 | Selective Serotonin Reuptake Inhibitors | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.