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Brain Diseases clinical trials

The registry lists 502 studies for Brain Diseases across more than 10 countries. 141 are recruiting or about to start. 77 of them are mainly about Brain Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 158 narrower conditions too, such as Stroke: 42,253 studies, 10,123 open.

ClinicalTrials.gov finds 42,281 studies for Brain Diseases. How that becomes 502 here

This page counts the studies the registry files under Brain Diseases, and those it files under no condition that list Brain Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 42,281Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −36,709Filed under a narrower condition, counted on its own pageStroke 7,740 · Parkinson Disease 4,358 · Alzheimer Disease 3,656 · Brain Neoplasms 2,309 · Cerebral Palsy 1,777 · Ischemic Stroke 1,728 · 144 more
  3. −34List Brain Diseases as a condition, but the registry did not file them under itMost often written as “Posterior Reversible Encephalopathy Syndrome” (6), “Sepsis-Associated Encephalopathy” (6), and “Gut-Brain Disorders” (3). The registry filed them under other conditions only, most often Sepsis-Associated Encephalopathy (8) and Posterior Leukoencephalopathy Syndrome (6).
  4. −5,036Match it another way9 name it in the title, 7 in a keyword, and 5,020 by a synonym or other text the search reads.
  5. 502The count on this page

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Status

Completed
236
Recruiting
106
Status unknown
45
Terminated
40
Not yet recruiting
28
Active, not recruiting
21

Phase

Phase 2
93
Phase 3
45
Phase 1
42
Phase 4
17
Early Phase 1
1

Where

United States
221
France
63
Germany
49
Canada
46
United Kingdom
41
China
41

Who runs them

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (10) · Assistance Publique - Hôpitaux de Paris (8) · Washington University School of Medicine (7) · Chinese University of Hong Kong (7) · Tammie L. S. Benzinger, MD, PhD (6) · National Institute of Mental Health (NIMH) (6) · Eli Lilly and Company (6) · National Institute of Allergy and Infectious Diseases (NIAID) (5)

What is being tested here

Drugs under test in Brain Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
ML-007C304
Islet Amyloid Polypeptide202
Donanemab113
Tenecteplase112
Amantadine101
Tocilizumab111
Nicotinamide-beta-riboside101
Elacestrant101
G 207101
Oncolytic HSV-1 G207101

Drug classes tested here Cholinesterase inhibitors 8 · Dopamine agonists 7 · SSRIs 6 · Antipsychotics 3

Coming up

9phase 3 studies under way
47studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 106 Brain Diseases studies recruiting now, 51 (48%) set no upper age limit and 21 (20%) stop at 75 or younger. 16 (15%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 22 (21%) take healthy volunteers.

Recruiting studies that take each age, of 106
AgeWomenMen
1012 (11%)12 (11%)
1875 (71%)74 (70%)
3079 (75%)78 (74%)
4083 (78%)82 (77%)
5089 (84%)88 (83%)
6597 (92%)96 (91%)
7591 (86%)90 (85%)
8571 (67%)70 (66%)

Across all 502 studies, recruiting or not: 28% stop at 75 or younger and 21% at 65; 23% take children; 1% are for women only and 1% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Brain Diseases studies take

Of 32 phase 2 interventional studies under Brain Diseases, half reached primary completion within 23 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 223 mo19–39 · 32 studies——
Phase 354 mo40–56 · 16 studies——
Interventional, no phase33 mo14–54 · 117 studies—35 mo14–57 · 99 studies
Observational62 mo22–193 · 87 studies—62 mo23–193 · 78 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 502. Browse all 502 → or search them.