Drug
Tramadol clinical trials
Also written Tramal and Ultram.
- studies test it
- 183
- open now
- 17
- in phase 3
- 44
- first study started
- 2000
Keep track of what changes. Save the Tramadol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
182 studies that test it; most in 2016 (16)
| Year | Studies |
|---|---|
| 2000 | 3 |
| 2001 | 1 |
| 2002 | 5 |
| 2003 | 3 |
| 2005 | 4 |
| 2006 | 7 |
| 2007 | 8 |
| 2008 | 9 |
| 2009 | 8 |
| 2010 | 3 |
| 2011 | 5 |
| 2012 | 7 |
| 2013 | 4 |
| 2014 | 7 |
| 2015 | 10 |
| 2016 | 16 |
| 2017 | 9 |
| 2018 | 11 |
| 2019 | 6 |
| 2020 | 8 |
| 2021 | 7 |
| 2022 | 11 |
| 2023 | 10 |
| 2024 | 10 |
| 2025 | 6 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 25
- Phase 2
- 27
- Phase 3
- 44
- Phase 4
- 63
- No phase
- 32
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 52 · Other 131
Cairo University (12) · Janssen Korea, Ltd., Korea (6) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (6) · Bausch Health Americas, Inc. (6) · Assiut University (4) · Labopharm Inc. (4) · Avenue Therapeutics, Inc. (3) · Janssen Pharmaceutical K.K. (3)
Often tested with
Tested in the same studies.
Acetaminophen (29) · Diclofenac (12) · Ketamine (9) · Celecoxib (9) · Morphine (8) · Dexmedetomidine (8) · Ketorolac (8) · Bupivacaine (6)
Studies
Open first, then newest update. How each study uses Tramadol is read from its arms, and is right about nine times in ten.
Testing it · 183
- Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingPhase 4Northwestern UniversityNCT07840183Written as Tramadol
- Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive CrisisNot yet recruitingPhase 4Assistance Publique - Hôpitaux de ParisNCT07826988Written as Goup 05 : Paracetamol + Morphine + Tramadol
- NonNarcotic Pain Control in Percutaneous Needle Tenotomy of ElbowRecruitingPhase 4The Cleveland ClinicNCT06373978Written as Tramadol
- Effects of Intraarticular Tramadol and Tramadol-Dexamethasone on Postoperative Pain After Knee ArthroscopyNot yet recruitingPhase 4Arzu Esen TekeliNCT07064993Written as Tramadol
- Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active LaborRecruitingPhase 4Universidad Nacional Autonoma de HondurasNCT07440069Written as Tramadol Hydrochloride
- Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder DiscomfortRecruitingPhase 3Al-Azhar UniversityNCT06274333Written as Tramadol 1mg/kg
- Combined Intravenous Tramadol and Paracetamol Versus Intramuscular Pethidine for Pain Relief During the First Stage of Labor. Compare the Efficacy and Adverse EffectsRecruitingNot applicableZohar NachumNCT07264309Written as Tramadol
- Nalbuphine Versus Tramadol on Post Operative Analgesia in Abdominal Surgery on Pediatric Cancer PatientRecruitingNot applicableNational Cancer Institute, EgyptNCT07110051Written as Tramadol
- Comparison Of The Effect Of Final Rinse Of Tramadol and Dexamethasone on Post-Endodontic Pain in Teeth With SIPEnrolling by invitationNot applicableDow University of Health SciencesNCT07036237Written as Tramadol group
- Use of Iv Tramadol and Ketamine for Prevention of Post Spinal Anesthesia ShiveringRecruitingPhase 3Liaquat National Hospital & Medical CollegeNCT06722742Written as Tramadol
- Intravenous Tramadol and Magnesium Sulphate for Prevention of ShiveringNot yet recruitingPhase 4Al-Azhar UniversityNCT06612996Written as Tramadol
- Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case SurgeriesEnrolling by invitationEarly Phase 1Zagazig UniversityNCT06561672Written as tramadol plus paracetamol
- Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular FunctionRecruitingPhase 4University of ZurichNCT03781544Written as Tramadol
- Tapentadol vs Tramadol in Total Knee ArthroplastyRecruitingPhase 4University of ThessalyNCT06269770Written as Tramadol
- Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic SurgeryNot yet recruitingPhase 4Baskent UniversityNCT06172920Written as Tramadol hydrochloride
- Tramadol and Tramadol Plus Ketamine for Shivering Prevention After Spinal Anesthesia in Lower Segment Caeserian SectionRecruitingPhase 4Ziauddin UniversityNCT06134895Written as Tramadol with Ketamine
- Pain Management in Pediatric AdenotonsillectomyNot yet recruitingPhase 3Al-Azhar UniversityNCT05928520Written as Tramadol 5%
- Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine SurgeryCompletedPhase 4Aristotle University Of ThessalonikiNCT04391855Written as Tramadol with ropivacaine
- Prophylactic Tramadol Versus Magnesium Sulphate for Prevention of Post-Spinal ShiveringCompletedNot applicablePunjab Rangers Teaching Hospital LahoreNCT07838662Written as Tramadol
- Paracetamol Plus Tramadol Versus Fentanyl in Day Case SurgeriesCompletedPhase 4Zagazig UniversityNCT05990686Written as tramadol plus paracetamol
See all 183 studies that test Tramadol →
Given in every arm · 35 — Tramadol is usual care beside what is tested
- Comparison of Two Postoperative Care Strategies After Breast SurgeryRecruitingNot applicableMoumtzidou Maria AikateriniNCT07880223Written as Tramadol
- Nephrostomy Tract Infiltration for Pain Control After PCNLRecruitingNot applicableHitit UniversityNCT07721571Written as Intravenous Tramadol and Paracetamol
- The Effect of Naldemedine on Opioid-induced Bowel DysfunctionRecruitingPhase 2Asbjørn Mohr DrewesNCT06334198Written as Tramadol
- EXORA Block vs Epidural Analgesia in Gynecological SurgeryActive, not recruitingNot applicableBursa Yuksek Ihtisas Training and Research HospitalNCT07346872Written as Tramadol
- The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKACompletedNot applicableDamascus UniversityNCT06112548Written as Tramadol
- Opioid-Free Pain Protocol After Shoulder ArthroplastyActive, not recruitingPhase 4Henry Ford Health SystemNCT05488847Written as Tramadol
- Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer PainCompletedNot applicableAssiut UniversityNCT05311774Written as Tramadol
- Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer PatientsCompletedPhase 2Medical College of WisconsinNCT04752384Written as Tramadol
- Effect of Transversus Thoracic Muscle Plane Block (TTMP) on AnalgesiaCompletedPhase 4Istanbul University - CerrahpasaNCT06601530Written as Tramadol
- Evaluation of the Efficacy of Regional Anaesthesia for Analgesia After Laparoscopic CholecystectomyCompletedNot applicableBursa Yüksek İhtisas Education and Research HospitalNCT06008002Written as Tramadol
- OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant PatientsCompletedPhase 4Hersh, Elliot V., DMD, MS, PhDNCT04694300Written as Tramadol
- Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder SurgeryCompletedNot applicableBezmialem Vakif UniversityNCT05401916Written as Tramadol
- Treatment of Neuropathic Pain in LeprosyStatus unknownPhase 3University of Sao PauloNCT03324035Written as Tramadol
- Rhomboid Intercostal and Subserratus Plane BlockCompletedNot applicableBursa Yüksek İhtisas Education and Research HospitalNCT04761029Written as Tramadol
- The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC)CompletedPhase 2Iuliu Hatieganu University of Medicine and PharmacyNCT02839668Written as Tramadol
- The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee ArthroplastyCompletedNot applicableRothman Institute OrthopaedicsNCT04003350Written as Tramadol
- TAP Block and Subacute Pain in Inguinal HerniographyCompletedNot applicableIstanbul UniversityNCT02914028Written as Tramadol and paracetamol
- Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic CholecystectomyCompletedPhase 4B.P. Koirala Institute of Health SciencesNCT02327923Written as Tramadol
- Comparing Protocols for Analgesia Following Elective Cesarean SectionStatus unknownPhase 4Wolfson Medical CenterNCT03622489Written as Tramadol
- Tramadol vs.Tramadol With ParacetamolCompletedNot applicableYeditepe University HospitalNCT03482492Written as Tramadol
Showing 20 of 35.
As the comparator · 45 — what is tested is compared with Tramadol
- Efficacy and Safety of DNN.63.18.040 for the Treatment of Moderate to Severe PainNot yet recruitingPhase 3Ache Laboratorios Farmaceuticos S.A.NCT07880392Written as Tramal®
- Comparison of Low-Dose Intravenous Ketamine and Tramadol for Prevention of Post-Spinal Anaesthesia Shivering in Orthopedic Surgical PatientsNot yet recruitingNot applicableShaheed Mohtarma Benazir Bhutto Institue of TraumaNCT07787702Written as Tramadol
- Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer PatientsEnrolling by invitationNot applicableMayo Hospital LahoreNCT07606638Written as Tramadol
- Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip ArthroplastyEnrolling by invitationPhase 4Mayo ClinicNCT07153003Written as Tramadol and Oxycodone
- A Phase Ⅱ/Ⅲ Study of HRS-2129 for Postsurgical Pain Management in Abdominal SurgeryRecruitingPhase 2/3Shandong Suncadia Medicine Co., Ltd.NCT07185594Written as Tramadol Hydrochloride SR Tablets
- Fascia Iliaca Compartment Block and Tramadol for Analgesia in Hip FractureNot yet recruitingNot applicableWest China HospitalNCT06728033Written as Tramadol
- Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third MolarsNot yet recruitingPhase 3EMSNCT06237231Written as TRAMADOL
- Efficacy and Safety of APSCTC for the Treatment of Postsurgical Pain Due to Third Molar ExtractionCompletedPhase 3Apsen Farmaceutica S.A.NCT04647435Written as Tramal®
- THIS STUDY AIMS TO COMPARE TWO DRUGS KETAMINE AND TRAMAL IN PREVENTION OF SHIVERING IN PATIENTS UNDERGOING SPINAL ANESTHESIA STUDY POPULATION IS PT UNDERGOING C SECTION . DOSE OF KETAMINE IS 0.25mg/kg and That of TRAMAL 0.5mg/kg.CompletedPhase 2KRL Hospital, IslamabadNCT07784556Written as Tramadol
- Comparison of Ultrasound-Guided Fascia Iliaca Compartment Block Versus Intravenous Tramadol for Positioning of Femur Fracture Patients Before Spinal AnaesthesiaCompletedNot applicableMayo Hospital LahoreNCT07735884Written as Tramadol
- Clinical Study of HRS-2129 for Postoperative Analgesia in OrthopaedicsCompletedPhase 1/2Shandong Suncadia Medicine Co., Ltd.NCT06780267Written as Tramadol Hydrochloride SR Tablets
- Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following HerniorrhaphyCompletedPhase 3Viatris Specialty LLCNCT06215859Written as Tramadol
- Intravenous Paracetamol Versus Intramuscular Tramadol in Shortening the Duration of Labour.CompletedNot applicableFederal Teaching Hospital AbakalikiNCT07394491Written as Tramadol hydrochloride
- Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following BunionectomyCompletedPhase 3Viatris Specialty LLCNCT06215820Written as Tramadol
- A Study to Evaluate the Efficacy and Safety of HR18042 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.TerminatedPhase 2Jiangsu HengRui Medicine Co., Ltd.NCT05470075Written as Tramadol hydrochloride SR Tablets
- A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth.CompletedPhase 2Jiangsu HengRui Medicine Co., Ltd.NCT04812860Written as Tramadol hydrochloride ER
- Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative PainCompletedPhase 2Laboratorios LiomontNCT05995912Written as Tramadol
- Efficacy and Safety of Tiradentes Association in the Treatment of Acute PainWithdrawnPhase 2EMSNCT04593329Written as TRAMADOL
- Efficacy and Safety of Canadá Association in the Treatment of Chronic PainWithdrawnPhase 2EMSNCT05125978Written as Tramadol hydrochloride
- Ultrasound-guided Rectus Sheath Block In ChildrenCompletedPhase 4Cukurova UniversityNCT02291705Written as Tramadol
Showing 20 of 45.
Codes
What other systems call Tramadol · ClinicalTrials.gg INT008338
- MeSH (NLM) D014147TramadolConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 39J1LGJ30JTRAMADOLConfirmed FDA, NLM, Wikidata
- RxNorm 10689Confirmed FDA, Wikidata
- Wikidata Q27145507tramadol hydrochlorideConfirmed FDA, NLM, Wikidata
- Wikidata Q407592tramadolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29507TramadolOne source FDA
- DrugBank DB00193One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014147 | Tramadol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 39J1LGJ30J | TRAMADOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10689 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27145507 | tramadol hydrochloride | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q407592 | tramadol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29507 | Tramadol | One source FDA |
| DrugBank | DB00193 | — | One source Wikidata |
Also registered as tramadol hydrochloride (UNII 9N7R477WCK · RxNorm 82110).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.