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Osteoarthritis clinical trials

The registry lists 2,974 studies for Osteoarthritis across more than 10 countries. 438 are recruiting or about to start. 1,897 of them are mainly about Osteoarthritis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Osteoarthritis, Knee: 5,981 studies, 1,040 open.

ClinicalTrials.gov finds 6,485 studies for Osteoarthritis. How that becomes 2,973 here

This page counts the studies the registry files under Osteoarthritis, and those it files under no condition that list Osteoarthritisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 6,485Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −3,004Filed under a narrower condition, counted on its own pageOsteoarthritis, Knee 2,537 · Osteoarthritis, Hip 403
  3. −171List Osteoarthritis as a condition, but the registry did not file them under itMost often written as “Shoulder Osteoarthritis” (17), “Degenerative Osteoarthritis” (13), and “Hand Osteoarthritis” (10). The registry filed them under other conditions only, most often Joint Diseases (23) and Arthritis, Rheumatoid (22).
  4. −337Match it another way240 name it in the title, 19 in a keyword, and 78 by a synonym or other text the search reads.
  5. 2,973The count on this page274 of them list Osteoarthritis in their own words; the registry filed them under no condition.

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Status

Completed
1,708
Status unknown
315
Recruiting
287
Terminated
235
Active, not recruiting
163
Not yet recruiting
116

Phase

Phase 2
368
Phase 3
331
Phase 4
258
Phase 1
187
Early Phase 1
24

Where

United States
1,029
Canada
205
United Kingdom
167
France
136
Germany
131
Denmark
120

Who runs them

Zimmer Biomet (85) · Pfizer (34) · Smith & Nephew, Inc. (33) · DePuy International (30) · DePuy Orthopaedics (29) · Istituto Ortopedico Rizzoli (27) · Ottawa Hospital Research Institute (22) · University of Aarhus (22)

What is being tested here

Drugs under test in Osteoarthritis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Platelet rich plasma4625
Triamcinolone3422
Tranexamic Acid3415
Hyaluronic Acid2115
Metformin203
Berobenatide222
Prednisone202
Triamcinolone Acetonide1418
Celecoxib1313
Duloxetine1211

Drug classes tested here Corticosteroids 5 open · NSAIDs 4 open · Antifibrinolytics 3 open · COX-2 inhibitors 1 open · SNRIs 1 open

Coming up

35phase 3 studies under way
164studies finish main data collection within a year9 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 287 Osteoarthritis studies recruiting now, 158 (55%) set no upper age limit and 72 (25%) stop at 75 or younger. 22 (8%) take children under 18. 3 (1%) are for women only and 0 (0%) for men only; 30 (10%) take healthy volunteers.

Recruiting studies that take each age, of 287
AgeWomenMen
1019 (7%)18 (6%)
18167 (58%)166 (58%)
30189 (66%)188 (66%)
40230 (80%)228 (79%)
50266 (93%)264 (92%)
65267 (93%)265 (92%)
75240 (84%)238 (83%)
85190 (66%)189 (66%)

Across all 2,974 studies, recruiting or not: 26% stop at 75 or younger and 9% at 65; 7% take children; 2% are for women only and 1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Osteoarthritis studies take

Of 84 phase 3 interventional studies under Osteoarthritis, half reached primary completion within 17 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 120 mo9–47 · 58 studies11 mo5–26 · 35 studies—
Phase 1/232 mo12–47 · 25 studies——
Phase 219 mo10–38 · 82 studies17 mo9–32 · 54 studies—
Phase 317 mo11–27 · 84 studies15 mo10–22 · 60 studies—
Phase 428 mo11–60 · 63 studies—28 mo14–60 · 54 studies
Interventional, no phase29 mo11–58 · 713 studies38 mo15–81 · 135 studies26 mo10–52 · 578 studies
Observational57 mo21–141 · 228 studies93 mo43–184 · 82 studies36 mo12–97 · 146 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting3

Results posted1

Stopped2

Newly registered12

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Studies

Recruiting first, then most recently updated. Showing 50 of 2,974. Browse all 2,974 → or search them.