Colic clinical trials
The registry lists 127 studies for Colic across more than 10 countries. 18 are recruiting or about to start. 102 of them are mainly about Colic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Federico II University (5) · BioGaia AB (5) · The University of Texas Health Science Center, Houston (4) · Menarini Group (4) · Karamanoğlu Mehmetbey University (3) · European School of Osteopathy (2) · Nordic Institute of Chiropractic and Clinical Biomechanics (2) · Société des Produits Nestlé (SPN) (2)
What is being tested here
Drugs under test in Colic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial · University of Aarhus
- Jul 2027The Effect of Probiotics in Infantile Colic · Federico II University
- Oct 2027Evaluating the Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With Colic · BioGaia AB
Who these studies take
Of the 11 Colic studies recruiting now, 2 (18%) set no upper age limit and 9 (82%) stop at 75 or younger. 9 (82%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (36%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 2 (18%) | 2 (18%) |
| 30 | 2 (18%) | 2 (18%) |
| 40 | 2 (18%) | 2 (18%) |
| 50 | 2 (18%) | 2 (18%) |
| 65 | 2 (18%) | 2 (18%) |
| 75 | 2 (18%) | 2 (18%) |
| 85 | 2 (18%) | 2 (18%) |
Across all 127 studies, recruiting or not: 91% stop at 75 or younger and 88% at 65; 80% take children; 6% are for women only and 0% for men only; 31% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Colic studies take
Of 44 interventional studies with no phase under Colic, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo10–40 · 44 studies | — | 17 mo8–40 · 32 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered2
- The Effect of Probiotics in Infantile ColicOct 26, 2026NCT07894445
- STUDY OF THE EFFECTS OF L. CASEI DG® (ENTEROLACTIS BABY) IN HEALTHY PRETERM AND FULL-TERM INFANTS.Oct 20, 2026NCT07882537
Studies
Recruiting first, then most recently updated. Showing 50 of 127. Browse all 127 → or search them.
- The Effect of Probiotics in Infantile ColicRecruitingNCT07894445Not applicable1 country
- Use of Bifidobacterium Bifidum in Formula-Fed Infants With Colic, With or Without Atopic DermatitisRecruitingNCT07754968Not applicable1 country
- Preventive Effect of a Dietary Supplement With Two Probiotic Limosilactobacillus Reuteri Strains on Excessive Crying and Colic in Healthy Newborns.RecruitingNCT07347743Not applicable1 country
- BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 MonthsRecruitingNCT07148583Not applicable1 country
- Study on the Immediate Analgesic Effect of Yanglingquan Acupoint Treatment for Biliary ColicNot yet recruitingNCT07194655Not applicable
- Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue)Not yet recruitingNCT071210621 country
- Prevalence of FGIDs and Probiotics StudyRecruitingNCT06309199Not applicable1 country
- Effect of a Dietary Supplement vs Low-dosage Product on Infant Gastrointestinal Discomfort and ColicsNot yet recruitingNCT07017244Not applicable1 country
- Vimala Massage Infantile Colic, Sleep and Development LevelsNot yet recruitingNCT06993701Not applicable1 country
- The Effect of Cranial Osteopathy Intervention in Preterm BabiesNot yet recruitingNCT06967870Not applicable1 country
- Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.RecruitingNCT060310251 country
- Clinical and Biological Database in Colon Cancer and Colic TumorsRecruitingNCT03976960Not applicable1 country
- Evolution of Functional Gastrointestinal Disorders in Infants Fed With a New Infant FormulaRecruitingNCT06488274Not applicable1 country
- 0-3 Months Infantile Colic The Effect of Ocean Sound on BabiesNot yet recruitingNCT06743971Not applicable
- The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention TrialRecruitingNCT06452199Not applicable1 country
- Effect of Probiotics on Infantile Colic SymptomsRecruitingNCT06385054Phase 21 country
- A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone DiseaseRecruitingNCT06405906Not applicable1 country
- Supportive Care Training Given to Mothers of Babies With Infants ColicNot yet recruitingNCT06197100Not applicable1 country
- STUDY OF THE EFFECTS OF L. CASEI DG® (ENTEROLACTIS BABY) IN HEALTHY PRETERM AND FULL-TERM INFANTS.CompletedNCT07882537Not applicable1 country
- The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before ExerciseCompletedNCT05217589Not applicable1 country
- Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying Time in Infants With ColicCompletedNCT05512234Not applicable3 countries
- Evaluating the Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With ColicActive, not recruitingNCT07190859Not applicable1 country
- Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms ReliefCompletedNCT05432479Not applicable2 countries
- RELIEF-pathway in Patients With Upper Abdominal PainActive, not recruitingNCT06002516Not applicable1 country
- The Effects of Reiki Therapy in Infants With ColicCompletedNCT07254520Not applicable1 country
- Effect of Probiotic Limosilactobacillus Reuteri (L. Reuteri) on Crying and Fussing Time in Infants With ColicCompletedNCT06462651Not applicable1 country
- The Effect of Thermal Heat Application on Colic in InfantsCompletedNCT07435948Not applicable1 country
- Prospective Study to Determine the Factors Influencing Infant ColicCompletedNCT05271747Not applicable2 countries
- Acupuncture in Infantile Colic - A Randomised Trial.WithdrawnNCT05894798Not applicable
- The Effect of Spa and Massage on Babies on Colic SymptomsCompletedNCT05538936Not applicable1 country
- Effect of Breastfeeding Mothers Drinking Fennel Seed Infusion on Infants With ColicCompletedNCT07236242Not applicable1 country
- Investigation of the Development of Infants With a History of ColicCompletedNCT068662491 country
- Effects of Osteopathic Manual Therapy on Infant ColicCompletedNCT04841590Not applicable1 country
- PRobiotics for EVEry Newborn TrialCompletedNCT04537494Not applicable1 country
- Bowel And Bladder Function in Infant Toilet TrainingActive, not recruitingNCT04082689Not applicable1 country
- The Effect of Colic Massage and Kangaroo Care on Babies and Their MothersCompletedNCT06727760Not applicable1 country
- The Role of Human Milk Oligosaccharides and Microbiomes on Infantile Colic and Atopic Dermatitis in Term InfantsActive, not recruitingNCT059924931 country
- Transition to Infant Formula Feeding on Gastrointestinal Regurgitation (TIGER) StudyCompletedNCT05363553Not applicable1 country
- EFFICACY OF A MIXTURE OF SIMETHICONE AND TYNDALLIZED BACILLUS COAGULANS IN INFANT COLIC: A PILOT STUDYCompletedNCT064588811 country
- Human Milk Oligosaccharide (HMO) Supplementation in Colic ManagementTerminatedNCT05554991Not applicable2 countries
- A Novel Iron Supplement for Athletes: Phase ICompletedNCT06285851Not applicable1 country
- Interventional Practices and Their Effectiveness in Infants With İnfantyl ColicActive, not recruitingNCT06299358Not applicable1 country
- Effect of Lactobacillus Reuteri DSM17938 in Neonates Treated With AntibioticsCompletedNCT02865564Not applicable1 country
- First Line Dose-efficacy Study of Bactecal® D Liquid for Infant ColicCompletedNCT05052476Not applicable1 country
- Effects of Vivatlac Baby on Crying Behavior of Colicky BabiesCompletedNCT04487834Phase 21 country
- Infantile Colic: Study of the Efficacy of Lactobacillus GG (ATCC 53103) Plus Chamomile in Breastfeeding InfantsTerminatedNCT03477669Not applicable1 country
- The Effect of Probiotics on Symptoms of Infantile ColicWithdrawnNCT05198700Phase 21 country
- Randomized Placebo-controlled Study of L. Reuteri NCIMB 30351 in GI Functional Disorders and Food Allergy in NewbornsCompletedNCT04262648Not applicable1 country
- Preliminary Efficacy, Safety and Pharmacokinetics Study of Nepadutant in Infant With Feeding IntoleranceCompletedNCT01532518Phase 21 country
- Combined Probiotics is More Effective in the Treatment of Infantile ColicCompletedNCT03877458Not applicable1 country