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Acute Pain clinical trials

The registry lists 1,073 studies for Acute Pain across more than 10 countries. 166 are recruiting or about to start. 693 of them are mainly about Acute Pain (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

ClinicalTrials.gov finds 3,108 studies for Acute Pain. How that becomes 1,073 here

This page counts the studies the registry files under Acute Pain, and those it files under no condition that list Acute Painthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,108Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −168List Acute Pain as a condition, but the registry did not file them under itMost often written as “Postoperative Pain, Acute” (77), “Post Operative Pain, Acute” (40), and “Acute Pain Due to Trauma” (10). The registry filed them under other conditions only, most often Pain, Postoperative (152) and Agnosia (22).
  3. −1,867Match it another way197 name it in the title, 27 in a keyword, and 1,643 by a synonym or other text the search reads.
  4. 1,073The count on this page15 of them list Acute Pain in their own words; the registry filed them under no condition.

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Status

Completed
684
Status unknown
111
Recruiting
101
Not yet recruiting
59
Terminated
51
Withdrawn
40

Phase

Phase 4
157
Phase 3
113
Phase 2
113
Phase 1
49
Early Phase 1
12

Where

United States
350
Turkey
158
Canada
61
Egypt
40
France
39
Italy
25

Who runs them

Assiut University (17) · University of Minnesota (14) · Montefiore Medical Center (14) · The University of Hong Kong (13) · Ondokuz Mayıs University (11) · Grünenthal GmbH (11) · University of Monastir (11) · Duke University (11)

What is being tested here

Drugs under test in Acute Pain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Bupivacaine4333
Liposomal Bupivacaine3112
Suzetrigine3210
Buprenorphine316
Lidocaine2420
Ketorolac2310
Sufentanil218
Ketorolac Tromethamine223
Buffered Lidocaine202
Ketamine1737

Drug classes tested here Local anesthetics 7 open · Opioids 6 open · NSAIDs 3 open · Inhaled anesthetics 1 open · Corticosteroids 1 open

Coming up

4phase 3 studies under way
68studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 101 Acute Pain studies recruiting now, 39 (39%) set no upper age limit and 49 (49%) stop at 75 or younger. 21 (21%) take children under 18. 13 (13%) are for women only and 0 (0%) for men only; 24 (24%) take healthy volunteers.

Recruiting studies that take each age, of 101
AgeWomenMen
1011 (11%)11 (11%)
1883 (82%)72 (71%)
3083 (82%)70 (69%)
4082 (81%)70 (69%)
5078 (77%)68 (67%)
6570 (69%)64 (63%)
7556 (55%)52 (51%)
8545 (45%)41 (41%)

Across all 1,073 studies, recruiting or not: 50% stop at 75 or younger and 38% at 65; 17% take children; 10% are for women only and 2% for men only; 28% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Acute Pain studies take

Of 84 phase 4 interventional studies under Acute Pain, half reached primary completion within 19 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 17 mo3–17 · 33 studies——
Phase 210 mo5–23 · 40 studies——
Phase 2/313 mo10–20 · 14 studies——
Phase 314 mo7–25 · 53 studies11 mo6–15 · 28 studies20 mo10–27 · 25 studies
Phase 419 mo9–32 · 84 studies—20 mo11–32 · 79 studies
Interventional, no phase11 mo5–23 · 430 studies—12 mo5–23 · 424 studies
Observational15 mo5–41 · 74 studies—15 mo5–41 · 72 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting3

Results posted2

Stopped1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 1,073. Browse all 1,073 → or search them.