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Brain Injuries, Traumatic clinical trials

The registry lists 1,721 studies for Brain Injuries, Traumatic across more than 10 countries. 447 are recruiting or about to start. 1,181 of them are mainly about Brain Injuries, Traumatic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Brain Concussion: 2,264 studies, 591 open.

ClinicalTrials.gov finds 2,676 studies for Brain Injuries, Traumatic. How that becomes 1,721 here

This page counts the studies the registry files under Brain Injuries, Traumatic, and those it files under no condition that list Brain Injuries, Traumaticthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,676Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −505Filed under a narrower condition, counted on its own pageBrain Concussion 482 · Chronic Traumatic Encephalopathy 12 · Post-Concussion Syndrome 10
  3. −16List Brain Injuries, Traumatic as a condition, but the registry did not file them under itMost often written as “Brain Injury Traumatic Severe” (3), “Brain Injury Traumatic Severe (Diagnosis)” (2), and “Traumatic Brain Injury With Loss of Consciousness” (2). The registry filed them under other conditions only, most often Brain Injuries (6) and Consciousness Disorders (3).
  4. −435Match it another way128 name it in the title, 4 in a keyword, and 303 by a synonym or other text the search reads.
  5. 1,720Counted here and found by its search33 of them list Brain Injuries, Traumatic in their own words; the registry filed them under no condition.
  6. +1
    Counted here, but its search does not find them
  7. 1,721The count on this page

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Status

Completed
803
Recruiting
281
Status unknown
214
Not yet recruiting
132
Terminated
119
Withdrawn
70

Phase

Phase 2
170
Phase 3
94
Phase 1
79
Phase 4
62
Early Phase 1
24

Where

United States
907
France
98
Canada
69
China
59
Italy
45
United Kingdom
45

Who runs them

VA Office of Research and Development (55) · Kessler Foundation (44) · University of Washington (24) · Craig Hospital (16) · Assiut University (15) · Massachusetts General Hospital (15) · Assistance Publique - Hôpitaux de Paris (15) · The University of Texas Health Science Center, Houston (15)

What is being tested here

Drugs under test in Brain Injuries, Traumatic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Propranolol429
Dexmedetomidine428
Levetiracetam317
Tranexamic Acid346
Ketamine207
Memantine226
Magnesium Sulfate235
Hyperpolarized Carbon C 13 (1-13C) Pyruvate202
Lidocaine202
Mannitol137

Drug classes tested here Beta blockers 4 open · Local anesthetics 2 open · Stimulants 1 open · Statins 1 open · Serotonin receptor agonists 1 open

Coming up

22phase 3 studies under way
151studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 281 Brain Injuries, Traumatic studies recruiting now, 120 (43%) set no upper age limit and 119 (42%) stop at 75 or younger. 40 (14%) take children under 18. 0 (0%) are for women only and 5 (2%) for men only; 52 (19%) take healthy volunteers.

Recruiting studies that take each age, of 281
AgeWomenMen
1023 (8%)23 (8%)
18250 (89%)253 (90%)
30252 (90%)256 (91%)
40251 (89%)255 (91%)
50253 (90%)258 (92%)
65228 (81%)231 (82%)
75176 (63%)179 (64%)
85137 (49%)139 (49%)

Across all 1,721 studies, recruiting or not: 46% stop at 75 or younger and 37% at 65; 20% take children; <1% are for women only and 2% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Brain Injuries, Traumatic studies take

Of 46 phase 2 interventional studies under Brain Injuries, Traumatic, half reached primary completion within 53 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 152 mo34–66 · 27 studies——
Phase 253 mo30–… · 46 studies——
Phase 348 mo19–69 · 30 studies——
Phase 443 mo8–148 · 25 studies——
Interventional, no phase40 mo22–64 · 464 studies—41 mo23–64 · 442 studies
Observational49 mo23–95 · 250 studies—50 mo23–95 · 228 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting5

Results posted1

Stopped1

Newly registered15

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Studies

Recruiting first, then most recently updated. Showing 50 of 1,721. Browse all 1,721 → or search them.