Drug
Memantine clinical trials
Also written Namenda and Ebixa.
- studies test it
- 200
- open now
- 18
- in phase 3
- 51
- first study started
- 1996
Keep track of what changes. Save the Memantine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
198 studies that test it; most in 2005 (22); 1 more planned to start later
| Year | Studies |
|---|---|
| 1996 | 1 |
| 1997 | 1 |
| 1999 | 1 |
| 2000 | 1 |
| 2002 | 2 |
| 2003 | 3 |
| 2004 | 12 |
| 2005 | 22 |
| 2006 | 17 |
| 2007 | 17 |
| 2008 | 10 |
| 2009 | 14 |
| 2010 | 8 |
| 2011 | 6 |
| 2012 | 9 |
| 2013 | 4 |
| 2014 | 8 |
| 2015 | 5 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 9 |
| 2019 | 7 |
| 2020 | 4 |
| 2021 | 9 |
| 2022 | 5 |
| 2023 | 4 |
| 2024 | 6 |
| 2025 | 4 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 19
- Phase 2
- 71
- Phase 3
- 51
- Phase 4
- 55
- No phase
- 21
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 31 · Other 169
Forest Laboratories (11) · Massachusetts General Hospital (8) · H. Lundbeck A/S (6) · New York State Psychiatric Institute (6) · National Cheng-Kung University Hospital (5) · University of California, San Diego (4) · Stanford University (4) · Mclean Hospital (4)
Often tested with
Tested in the same studies.
Gabapentin (5) · Donepezil (5) · Dextromethorphan (4) · Rivastigmine (4) · Baclofen (3) · Escitalopram (3) · Melatonin (2) · Modafinil (2)
Studies
Open first, then newest update. How each study uses Memantine is read from its arms, and is right about nine times in ten.
Testing it · 200
- The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC)RecruitingPhase 2Inova Health Care ServicesNCT06789757Written as Memantine Hydrochloride
- Memantine Targeting Neurovascular Dysfunction After Mild and Moderate Traumatic Brain Injury (MEND)Not yet recruitingPhase 2Nova Scotia Health AuthorityNCT07867210Written as Memantine
- Escalating Doses of Memantine in Down Syndrome (MEDS-123)Not yet recruitingPhase 1University Hospitals Cleveland Medical CenterNCT07531940Written as Memantine
- A Prospective Study of Memantine in Patients With Cirrhosis and Liver CancerRecruitingPhase 2/3Inova Health Care ServicesNCT06007846Written as Namenda
- Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) TechniqueRecruitingPhase 2Medical College of WisconsinNCT05045950Written as Memantine -Twice Daily or Extended Release
- Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain MetastasesRecruitingPhase 3Canadian Cancer Trials GroupNCT03550391Written as Memantine
- Synaptic Mechanisms of Continuous Theta Burst Stimulation in DepressionRecruitingEarly Phase 1Mclean HospitalNCT07560878Written as Memantine
- Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast CancerRecruitingPhase 2UNC Lineberger Comprehensive Cancer CenterNCT06727773Written as Memantine
- NTS-WBRT in Brain MetastasesRecruitingPhase 2Massachusetts General HospitalNCT05013892Written as Memantine
- Neuroprotection of Memantine and RosuvastatinNot yet recruitingPhase 2/3Tanta UniversityNCT07504198Written as Memantine
- Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised TrialRecruitingPhase 2/3University of EdinburghNCT04302870Written as Memantine Hydrochloride Oral Solution
- Memantine Hydrochloride in Prostate Cancer PatientsNot yet recruitingPhase 2Bin XuNCT07164794Written as Memantine Hydrochloride
- Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSIRecruitingPhase 3Tata Memorial CentreNCT06275035Written as Memantine Oral Tablet
- Memantine as an Additive Therapy in Patients With Traumatic Brain InjuryNot yet recruitingPhase 2/3Mansoura UniversityNCT06914310Written as Memantine
- Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First PsychosisRecruitingPhase 1Bjorn H. EbdrupNCT04789915Written as Memantine
- "The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients"RecruitingPhase 2Ain Shams UniversityNCT06679387Written as Memantine-HCl
- Early Application of Memantine and Pioglitazone to Protect Cognitive Function After RadiotherapyNot yet recruitingPhase 2Affiliated Cancer Hospital & Institute of Guangzhou Medical UniversityNCT06594172Written as Memantine Oral Tablet
- Glutamate Inhibitors in GlioblastomaRecruitingPhase 1/2University of ZurichNCT05664464Written as Memantine
- Treatment of Orthostatic IntoleranceActive, not recruitingPhase 1/2Satish R. RajNCT00262470Written as memantine
- Efficacy and Tolerability of Memantine in Frontotemporal Dementia (FTD) PatientsCompletedPhase 2Nantes University HospitalNCT00200538Written as memantine
See all 200 studies that test Memantine →
Given in every arm · 11 — Memantine is usual care beside what is tested
- Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the BrainRecruitingPhase 2The University of Texas Health Science Center at San AntonioNCT07470606Written as Memantine
- Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)RecruitingPhase 2Case Comprehensive Cancer CenterNCT07248228Written as Memantine
- Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain MetastasesCompletedPhase 3NRG OncologyNCT02360215Written as Memantine
- Ultrasound-Guided Stellate Ganglion Block for Alzheimer's DiseaseCompletedNot applicableTaizhou Second People's HospitalNCT07351773Written as Memantine hydrochloride
- SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a StudyCompletedPhase 2Suven Life Sciences LimitedNCT02580305Written as Memantine
- The Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's DiseaseCompletedNot applicableIstanbul Medipol University HospitalNCT05102045Written as Memantine
- Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain MetastasesStatus unknownPhase 2National Taiwan University HospitalNCT04801342Written as Memantine Hydrochloride
- A FDG-PET Study of AGN-242071 Added to Standard-of-Care (Donepezil ± Memantine) for the Treatment of Participants With Mild to Moderate Alzheimer's DiseaseWithdrawnPhase 1AllerganNCT03316898Written as Memantine
- A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease TherapyCompletedPhase 2Hoffmann-La RocheNCT01677754Written as Memantine
- Memantine and Comprehensive, Individualized Management of Alzheimer's Disease and Caregiver TrainingCompletedPhase 4NYU Langone HealthNCT00120874Written as Memantine
- Alzheimer's Disease - Input of Vitamin D With mEmantine AssayCompletedPhase 3University Hospital, AngersNCT01409694Written as Memantine
As the comparator · 3 — what is tested is compared with Memantine
- Effect of Acetylcholinesterase Inhibitors on Bone MetabolismRecruitingPhase 2Duke UniversityNCT06041789Written as Memantine
- Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking AbilityActive, not recruitingPhase 3NRG OncologyNCT04804644Written as Memantine Hydrochloride
- Memantine for Enhanced Stroke RecoveryActive, not recruitingEarly Phase 1University of UtahNCT02144584Written as Memantine XR
Codes
What other systems call Memantine · ClinicalTrials.gg INT007785
- MeSH (NLM) D008559MemantineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) W8O17SJF3TMEMANTINEConfirmed FDA, NLM, Wikidata
- RxNorm 6719Confirmed FDA, Wikidata
- Wikidata Q412189memantineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73269MemantineOne source FDA
- DrugBank DB01043One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D008559 | Memantine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | W8O17SJF3T | MEMANTINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6719 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412189 | memantine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73269 | Memantine | One source FDA |
| DrugBank | DB01043 | — | One source Wikidata |
Also registered as memantine hydrochloride (UNII JY0WD0UA60 · RxNorm 236685).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.