Brain Injuries clinical trials
The registry lists 946 studies for Brain Injuries across more than 10 countries. 235 are recruiting or about to start. 475 of them are mainly about Brain Injuries (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 5 narrower conditions too, such as Brain Injuries, Traumatic: 2,981 studies, 781 open.
ClinicalTrials.gov finds 6,136 studies for Brain Injuries. How that becomes 945 here
This page counts the studies the registry files under Brain Injuries, and those it files under no condition that list Brain Injuriesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 6,136Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −2,031Filed under a narrower condition, counted on its own pageBrain Injuries, Traumatic 1,463 · Brain Concussion 449 · Post-Concussion Syndrome 42 · Post-Cardiac Arrest Syndrome 31 · Chronic Traumatic Encephalopathy 12
- −67List Brain Injuries as a condition, but the registry did not file them under itMost often written as “Anoxic Brain Injury” (8), “Disorders of Consciousness Due to Severe Brain Injury” (5), and “Brain Injury, Chronic” (4). The registry filed them under other conditions only, most often Hypoxia-Ischemia, Brain (17) and Stroke (12).
- −3,093Match it another way219 name it in the title, 29 in a keyword, and 2,845 by a synonym or other text the search reads.
- 945The count on this page22 of them list Brain Injuries in their own words; the registry filed them under no condition.
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Status
Who runs them
Rigshospitalet, Denmark (20) · VA Office of Research and Development (17) · University of Washington (12) · IRCCS Eugenio Medea (11) · Assistance Publique - Hôpitaux de Paris (11) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (11) · Icahn School of Medicine at Mount Sinai (9) · Sheba Medical Center (9)
What is being tested here
Drugs under test in Brain Injuries studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Human Growth Hormone | 1 | 0 | 3 |
| Tranexamic Acid | 1 | 1 | 2 |
| Levetiracetam | 1 | 0 | 2 |
| Lacosamide | 1 | 0 | 2 |
| Bevacizumab | 1 | 0 | 2 |
| Metformin | 1 | 0 | 1 |
| Cerebrolysin | 1 | 0 | 1 |
| Endostar protein | 1 | 0 | 1 |
| Creatine monohydrate | 1 | 0 | 1 |
| Creatine | 1 | 0 | 1 |
Drug classes tested here Angiogenesis inhibitors 2 open · Stimulants 5 · SSRIs 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Biperiden Trial for Epilepsy Prevention · Phase 3 · Hospital Sirio-Libanes
- Nov 2026Motor and Cognitive Telerehabilitation for Acquired Brain Injury · Azienda USL Toscana Nord Ovest
- Dec 2026fNIRS for Disorders of Consciousness · University of California, Los Angeles
- Dec 2026Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy · Universitaire Ziekenhuizen KU Leuven
- Dec 2026The Parkwood Pacing and Planning™ App · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Dec 2026Hemodynamic ABI Monitor · University of Chicago
- Dec 2026The Impact of Self-processing on Mental Time Travel · Istituti Clinici Scientifici Maugeri SpA
- Dec 2026TES HT100 Clinical Validation for Brain Injury Screening in Patients With Mild Head Trauma or Neurological Symptoms · B&B srl
- Dec 2026Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation · Tan Tock Seng Hospital
- Dec 2026NRF for Improved Re-Entry Outcomes for Offenders With Brain Injury (Brain Injury RE) · Icahn School of Medicine at Mount Sinai
Who these studies take
Of the 152 Brain Injuries studies recruiting now, 75 (49%) set no upper age limit and 55 (36%) stop at 75 or younger. 39 (26%) take children under 18. 3 (2%) are for women only and 0 (0%) for men only; 23 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 20 (13%) | 20 (13%) |
| 18 | 122 (80%) | 119 (78%) |
| 30 | 120 (79%) | 117 (77%) |
| 40 | 122 (80%) | 119 (78%) |
| 50 | 122 (80%) | 119 (78%) |
| 65 | 116 (76%) | 114 (75%) |
| 75 | 105 (69%) | 103 (68%) |
| 85 | 84 (55%) | 82 (54%) |
Across all 946 studies, recruiting or not: 39% stop at 75 or younger and 29% at 65; 29% take children; 1% are for women only and 1% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Brain Injuries studies take
Of 297 interventional studies with no phase under Brain Injuries, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo12–48 · 297 studies | — | 26 mo14–48 · 284 studies |
| Observational | 31 mo16–73 · 148 studies | — | 31 mo16–73 · 143 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Newly registered9
- Cognitive Rehabilitation of Executive Dysfunction With the Goal Management Training (GMT) - Exploring Variations in Mode of Administration, Frequency and Intensity.Nov 9, 2026NCT07924774
- Comprehensive Assessment of Rehabilitation Experience Using the SAFE ScaleNov 3, 2026NCT07912372
- Exploration of Whole-Brain Radiotherapy Combined With PD-1 Inhibitors on Brain InjuryOct 30, 2026NCT07905937
- Informational Needs of Caregivers of Patients With Neuromotor Disease in Rehabilitation Hospitalization: Validation Study of the QBI-R/VOct 29, 2026NCT07903298
- Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)Oct 29, 2026NCT07904624
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- Adverse Events During Physical Therapy in Neurocritical ICU PatientsOct 28, 2026NCT07901140
- Transition From Pediatric to Adult Care in Young Adults With Acquired Brain InjuryOct 19, 2026NCT07881042
- Dynamic, Real-world Learning, Innovative Mobility, and Versatile Exploration (DRIVE): Evaluating a Dose-matched Developmental Powered Mobility Intervention for Young Children With Cerebral PalsyOct 15, 2026NCT07876219
- Temporal Interference Stimulation for Disorders of ConsciousnessOct 14, 2026NCT07874178
Studies
Recruiting first, then most recently updated. Showing 50 of 946. Browse all 946 → or search them.
- Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain InjuryRecruitingNCT06848140Not applicable1 country
- Cognitive Rehabilitation of Executive Dysfunction With the Goal Management Training (GMT) - Exploring Variations in Mode of Administration, Frequency and Intensity.RecruitingNCT07924774Not applicable1 country
- Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain InjuryRecruitingNCT072151951 country
- Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower ExtremitiesRecruitingNCT07303582Phase 41 country
- The Impact of Self-processing on Mental Time TravelRecruitingNCT06823193Not applicable1 country
- Continuous Noninvasive Multimodal Neuromonitoring at the ICU After Cardiac ArrestEnrolling by invitationNCT079124111 country
- Comprehensive Assessment of Rehabilitation Experience Using the SAFE ScaleRecruitingNCT07912372Not applicable1 country
- Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)Not yet recruitingNCT07904624Not applicable1 country
- Exploration of Whole-Brain Radiotherapy Combined With PD-1 Inhibitors on Brain InjuryRecruitingNCT079059371 country
- Informational Needs of Caregivers of Patients With Neuromotor Disease in Rehabilitation Hospitalization: Validation Study of the QBI-R/VRecruitingNCT07903298Not applicable1 country
- The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain InjuryRecruitingNCT07331324Not applicable1 country
- Description of Clinicians' Predictive Abilities Before and After a Diffusion Tensor Imaging (DTI)Not yet recruitingNCT078634141 country
- Exercise and Physical Activity in Children With Pediatric Acquired Brain InjuryRecruitingNCT06804486Not applicable1 country
- Fareon Open Label Device Clinical TrialEnrolling by invitationNCT07600320Not applicable1 country
- Exercise and Physical Activity in Adults With Acquired Brain InjuryNot yet recruitingNCT06895226Not applicable1 country
- Prospective Observational Multimodal Neuromonitoring During High-Risk Adult SurgeryNot yet recruitingNCT075777261 country
- Temporal Interference Stimulation for Disorders of ConsciousnessNot yet recruitingNCT07874178Not applicable
- Dynamic, Real-world Learning, Innovative Mobility, and Versatile Exploration (DRIVE): Evaluating a Dose-matched Developmental Powered Mobility Intervention for Young Children With Cerebral PalsyNot yet recruitingNCT07876219Not applicable1 country
- Severe Acquired Brain Injuries: Prognostic Factors and Quality of CareRecruitingNCT049052641 country
- Advanced Space-time Resolved Techniques for Functional Neuroimaging at 7 Tesla MRIRecruitingNCT07865546Not applicable1 country
- Acceptability of Paediatric Wrist Orthoses Through Co-designRecruitingNCT07861958Not applicable1 country
- Visual Impairment and Functional Visual Performance Following Acquired Brain Injury: A Cross-Sectional StudyEnrolling by invitationNCT078587081 country
- Early Prophylactic Versus Late Salvage Recombinant Human Endostatin in Managing Radiosurgery-Induced Brain Injury for NSCLC Brain MetastasesNot yet recruitingNCT07841106Phase 2
- Pilot Study of Individualized Neurovisual Rehabilitation Following Acquired Brain InjuryNot yet recruitingNCT07849582Not applicable1 country
- Non-Invasive Monitoring Methods in Patients With Acute Brain InjuryRecruitingNCT065042381 country
- Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain InjuryRecruitingNCT077822161 country
- Retrospective Evaluation of Autonomic Activity Through Electrodermal Activity Measurement During RehabilitationNot yet recruitingNCT07835659
- Depth Electrode Cortical Reverberation Monitoring After Traumatic Brain InjuryRecruitingNCT07842458Not applicable1 country
- ECMO ABI Detection With HyperfineRecruitingNCT06469801Not applicable1 country
- Portable MRI for Pediatric Hypoxic Ischemic Brain InjuryRecruitingNCT07577336Not applicable1 country
- TES HT100 Clinical Validation for Brain Injury Screening in Patients With Mild Head Trauma or Neurological SymptomsRecruitingNCT07490418Not applicable2 countries
- Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill PatientsNot yet recruitingNCT07184593
- Multifaceted Intervention to Restore Resilience and Overcome RiskRecruitingNCT06988787Not applicable1 country
- Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSDRecruitingNCT05380050Not applicable1 country
- Baby Brain Recovery StudyRecruitingNCT050137361 country
- VR Versus Task-Oriented Circuit Training on UL Sensorimotor in Children With Immature Brain InjuryNot yet recruitingNCT07827365Not applicable
- Effects of Neurofeedback Training and tRNS on Attentional Deficits in Patients With Acquired Brain InjuryRecruitingNCT07817316Not applicable1 country
- Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled TrialRecruitingNCT06469983Not applicable1 country
- Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical SettingRecruitingNCT07745712Not applicable1 country
- Mobile Health Self-Management and Support System for Chronic and Complex Health ConditionsRecruitingNCT02592291Not applicable1 country
- Mesenchymal Stem Cells With Cooling Therapy for Infants With Hypoxic-Ischemic EncephalopathyNot yet recruitingNCT07018739Phase 1/21 country
- Screening Emotions in Adolescents at the Hospital for mTBIRecruitingNCT063705201 country
- Describing the Effect of Familiar Song on Arousal and Awareness for Children With Disorders of Consciousness (DoC)RecruitingNCT07209657Not applicable1 country
- PRophylaxis Against Early VENTilator-associated Infections in Acute Brain InjuryRecruitingNCT06819592Phase 33 countries
- AI Chatbot-Assisted Aerobic Exercise Guided by the Transtheoretical Model and Self-determination Theory With Machine Learning Algorithms to Provide Real-time, Personalized Feedback in Traumatic Brain InjuryRecruitingNCT07783828Not applicable1 country
- PRecisiOn Medicine In StrokE: Evolution of Plasma Brain-Derived Tau in Acute StrokeRecruitingNCT061213361 country
- Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain InjuryNot yet recruitingNCT077723231 country
- Effect of Functional Electrical Stimulation (FES) on Handwriting Rehabilitation After Acquired Brain Injury (ABI)RecruitingNCT07774715Not applicable1 country
- The Study of Ginkgo Leaf Dropping Pills and Huperzine A Injection Combined With Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain InjuryRecruitingNCT06704334Phase 41 country
- Ketamine Infusion as a Method of Cerebral Protection in ChildrenRecruitingNCT06525584Not applicable1 country