Drug class
Hydroxymethylglutaryl-CoA Reductase Inhibitors clinical trials
A class of medicines: the studies that test any of its 10 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the hydroxymethylglutaryl-coa reductase inhibitors studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Amlodipine, atorvastatin drug combination
- 4
- Ppd-10558
- 1
Studies by the year they started
1,699 studies that test it; most in 2007 (96); 1 more planned to start later
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1991 | 1 |
| 1993 | 1 |
| 1996 | 1 |
| 1997 | 1 |
| 1998 | 8 |
| 1999 | 3 |
| 2000 | 15 |
| 2001 | 14 |
| 2002 | 32 |
| 2003 | 55 |
| 2004 | 58 |
| 2005 | 92 |
| 2006 | 87 |
| 2007 | 96 |
| 2008 | 93 |
| 2009 | 78 |
| 2010 | 88 |
| 2011 | 74 |
| 2012 | 76 |
| 2013 | 67 |
| 2014 | 82 |
| 2015 | 86 |
| 2016 | 59 |
| 2017 | 58 |
| 2018 | 46 |
| 2019 | 51 |
| 2020 | 68 |
| 2021 | 59 |
| 2022 | 47 |
| 2023 | 51 |
| 2024 | 54 |
| 2025 | 50 |
| 2026 | 47 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 594 · Other 1,121
AstraZeneca (79) · Organon and Co (52) · Pfizer (34) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (31) · Merck Sharp & Dohme LLC (22) · Samsung Medical Center (19) · Yonsei University (19) · Chong Kun Dang Pharmaceutical (17)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 1,715
- Statin Effect on Arrhythmogenic Cardiomyopathy Disease Progression (SEARCH)RecruitingPhase 2Centro Cardiologico MonzinoNCT06922994Written as Atorvastatin 80 mg/day
- AtorvaStatin Postpartum and Reduction of Cardiovascular risKRecruitingPhase 4Ohio State UniversityNCT06632379Written as Atorvastatin 10 mg
- Aggressive Lipid Lowering Therapy in ICI-Treated MelanomaRecruitingNot applicableUniversity of Colorado, DenverNCT07704918Written as Statins (atorvastatin, rosuvastatin, simvastatin, or pravastatin), +/- ezetimibe, +/- PCSK9 inhibitor (alirocumab, evolocumab, inclisiran)
- Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) With Atorvastatin (ATORGO)Not yet recruitingPhase 2Region SkaneNCT07883356Written as Atorvastatin
- Fufang Tongluo Decoction as an Adjunct to Aspirin and Atorvastatin for Ischemic Moyamoya DiseaseEnrolling by invitationNot applicableThe First Affiliated Hospital with Nanjing Medical UniversityNCT07875335Written as Atorvastatin
- Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)RecruitingPhase 2Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauNCT07098975Written as Pravastatin 40 mg
- A Phase I Study of the Interaction of D-2570 With Other Drugs in Healthy AdultsNot yet recruitingPhase 1InventisBio Co., LtdNCT07875842Written as Rosuvastatin
- Precision Medicine Adaptive Network Platform Trial in Hypoxemic Acute Respiratory FailureNot yet recruitingPhase 2University of Colorado, DenverNCT07779642Written as Simvastatin
- A Clinical Trial of MK-6916 With Midazolam and Rosuvastatin in Healthy Participants (MK-6916-012)Not yet recruitingPhase 1Merck Sharp & Dohme LLCNCT07862621Written as Rosuvastatin
- Safety and Efficacy of Atorvastatin v. Placebo on HCC RiskRecruitingPhase 2Raymond ChungNCT05028829Written as Atorvastatin 20mg
- PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosisRecruitingPhase 3Duke UniversityNCT07232069Written as Rosuvastatin 20 Mg Oral Tablet
- Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United StatesRecruitingPhase 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05832229Written as Rosuvastatin
- Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast CancerNot yet recruitingPhase 2Washington University School of MedicineNCT07619365Written as Lovastatin
- The Role of Simvastatin in The Epithelial-Mesenchymal Transition Process of Breast CancerRecruitingPhase 2Universitas IndonesiaNCT05550415Written as Simvastatin 40mg
- VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent GliomaRecruitingPhase 2Inova Health Care ServicesNCT07831369Written as Simvastatin
- Pharmacologic Therapies to Mitigate Radiation- Associated Heart DiseaseRecruitingPhase 2UNC Lineberger Comprehensive Cancer CenterNCT07685938Written as Atorvastatin and Lisinopril
- Statins to Prevent Cancer Associated Blood ClotsRecruitingPhase 4Brigham and Women's HospitalNCT07303816Written as Rosuvastatin
- Topical Simvastatin for Treating Infantile HemangiomaNot yet recruitingEarly Phase 1Joyce TengNCT06273111Written as 5% simvastatin ointment
- Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)RecruitingPhase 2M.D. Anderson Cancer CenterNCT06494111Written as Pravastatin
- A Clinical Trial to Evaluate the Drug-drug Interactions of Co-administered 'HUC2-744-A' and 'HUC2-744-B' in Healthy Adult VolunteersNot yet recruitingPhase 1Huons Co., Ltd.NCT07784608Written as Atorvastatin Calcium
See all 1,715 studies that test one of the hydroxymethylglutaryl-coa reductase inhibitors →