An observational study in Traumatic Brain Injury, sponsored by Rutgers, The State University of New Jersey. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-28.
Sponsored by Rutgers, The State University of New Jersey · Observational
Prospective cohort study of 150 adults with moderate-to-severe TBI. Blood NfL is measured at admission, day 1, and day 3 to examine its relationship, alone and with CT imaging, to 3-month functional outcome (GOSE).
1,721 studies on the registry are indexed under Brain Injuries, Traumatic; 447 are open to participants now.
This study's planned enrollment of 175 is above the median of 117 across 557 observational studies indexed under Brain Injuries, Traumatic.
Browse Brain Injuries, Traumatic studies →Rutgers, The State University of New Jersey is the lead sponsor of 506 studies on the registry; 131 are open to participants now.
Of its 39 completed or terminated interventional studies of FDA-regulated products, 31 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Moderate-to-severe traumatic brain injury (TBI) is a major cause of death and long-term neurological disability. During acute hospitalization, clinicians must make consequential decisions and counsel patients and families about prognosis despite substantial uncertainty in individual recovery. Current prognostic assessment relies on clinical examination, injury severity, neuroimaging, and other established predictors, but these measures do not directly quantify the evolving neuroaxonal injury following TBI.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
University Hospital phlebotomists will collect blood during scheduled clinical blood collection at admission, day 1, and day 3, including one additional 1 mL research tube drawn at the same venipuncture, so no additional needle insertion is expected. Clinical care takes priority; collection will be deferred or omitted if the treating team considers it unsafe.
Glasgow Outcome Scale Extended
Time frame: 3 months post-injury
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Rutgers, The State University of New Jersey →