Drug
Tranexamic Acid clinical trials
Also written Cyklokapron, Lysteda, Cyclokapron and XP12B.
Keep track of what changes. Save the Tranexamic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
588 studies that test it; most in 2021 (50); 2 more planned to start later
| Year | Studies |
|---|---|
| 2003 | 2 |
| 2004 | 1 |
| 2005 | 5 |
| 2006 | 8 |
| 2007 | 2 |
| 2008 | 8 |
| 2009 | 9 |
| 2010 | 14 |
| 2011 | 13 |
| 2012 | 21 |
| 2013 | 23 |
| 2014 | 30 |
| 2015 | 33 |
| 2016 | 34 |
| 2017 | 25 |
| 2018 | 49 |
| 2019 | 38 |
| 2020 | 43 |
| 2021 | 50 |
| 2022 | 41 |
| 2023 | 39 |
| 2024 | 35 |
| 2025 | 31 |
| 2026 | 34 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 20 · Other 571
Assiut University (19) · Cairo University (18) · Aswan University Hospital (12) · London School of Hygiene and Tropical Medicine (9) · NYU Langone Health (9) · Ain Shams University (8) · Chinese Academy of Medical Sciences, Fuwai Hospital (7) · Northwestern University (6)
Often tested with
Tested in the same studies.
Epinephrine (8) · Aminocaproic Acid (8) · Misoprostol (7) · Oxytocin (5) · Protease Inhibitor Formulation LB1148 (5) · Fibrin Tissue Adhesive (3) · Arginine Vasopressin (3) · Calcium Dobesilate (2)
Related medicines
As reviewed, each with the page that says it.
- One of Antifibrinolytic Agents source
Studies
Open first, then newest update. How each study uses Tranexamic Acid is read from its arms, and is right about nine times in ten.
Testing it · 591
- Extended Post-Operative Oral Tranexamic Acid Dosing After ACL ReconstructionNot yet recruitingPhase 3Dave BernholtNCT07880743Written as Tranexamic Acid
- Baseline Dermoscopic Vascular Score and Response to Oral Tranexamic Acid in Facial MelasmaNot yet recruitingPhase 4Allied Hospital FaisalabadNCT07881328Written as Tranexamic acid
- Prevention of Postpartum Hemorrhage With Tranexamic AcidRecruitingPhase 2Inova Health Care ServicesNCT05370820Written as Tranexamic acid
- Tranexamic Acid to Reduce Blood Loss After Varus Derotation OsteotomyNot yet recruitingPhase 3Murdoch Childrens Research InstituteNCT07672158Written as Tranexamic Acid (IV)
- Intraosseous Tranexamic Acid for Reducing Blood Loss in Total Knee ArthroplastyNot yet recruitingPhase 4The Second Affiliated Hospital of Kunming Medical UniversityNCT07853885Written as Tranexamic Acid
- Tranexamic Acid for Bleeding Reduction During TURP SurgeryRecruitingPhase 4Hamza NajoutNCT07460518Written as Tranexamic Acid
- The Safety of Simplified Tranexamic Acid RegimenRecruitingPhase 4Second Affiliated Hospital, Zhejiang University, School of MedicineNCT07869537Written as Tranexamic Acid (TXA)
- Topical Tranexamic Acid Spray Versus No Spray on Postoperative Outcomes Following Mesh Repair of Umbilical HerniaNot yet recruitingNot applicableDr Mudassar Saeed PansotaNCT07845370Written as Topical Tranexamic Acid Spray
- Comparison Between Efficacy of Inhaled VS Intravenous Tranexamic Acid for HemoptysisEnrolling by invitationPhase 4Dow University of Health SciencesNCT07845747Written as Tranexamic Acid
- HTO and Tranexamic Acid StudyNot yet recruitingPhase 3Western University, CanadaNCT07825350Written as Tranexamic Acid
- Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in ChildrenRecruitingPhase 3Philip SpinellaNCT06070350Written as Tranexamic Acid (TXA)
- Evaluating the Effectiveness of Intramuscular Versus Intravenous Tranexamic Acid for Minimizing Blood Loss After Total Hip Arthroplasty: A Randomized Controlled TrialRecruitingEarly Phase 1Alexandria UniversityNCT07817537Written as Tranexamic Acid (TXA) intravenous
- Evaluating the Effectiveness and Safety of Microneedling With Topical Tranexamic Acid in Treatment of Striae RubraNot yet recruitingNot applicableSohag UniversityNCT07795515Written as Topical tranexamic acid
- Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin GraftRecruitingPhase 4University of Kansas Medical CenterNCT06379724Written as Tranexamic acid
- Tranexamic Acid for Anaemia TrialRecruitingPhase 3London School of Hygiene and Tropical MedicineNCT06519422Written as Tranexamic Acid 500 MG
- The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic SurgeryRecruitingPhase 4St. Olavs HospitalNCT06270407Written as Tranexamic Acid 100 MG/ML
- Extended Oral Tranexamic Acid After Total Knee ArthroplastyEnrolling by invitationPhase 3Campbell ClinicNCT06618820Written as Tranexamic acid
- REDUCER Trial (TXA in Urethroplasty)Not yet recruitingPhase 4Amjad Alwaal, MD, MSc, FRCSC, FACSNCT07501884Written as Tranexamic Acid
- Prospective Study: TXA, Anticoagulant, Orthopaedic TraumaNot yet recruitingPhase 4Arbi Nazarian, MDNCT07116395Written as Tranexamic Acid (TXA)
- Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint ArthroplastyRecruitingPhase 4Mayo ClinicNCT06832878Written as Oral Tranexamic Acid
See all 591 studies that test Tranexamic Acid →
Given in every arm · 13 — Tranexamic Acid is usual care beside what is tested
- Kaolin-based Hemostatic Gauze in Total Knee ArthroplastyCompletedPhase 4Chang Gung Memorial HospitalNCT05504577Written as Tranexamic acid injection
- A Trial of Intraoperative Fibrin Sealant on Postoperative Recovery After Total Knee ReplacementCompletedPhase 4Singapore General HospitalNCT07455591Written as Tranexamic Acid (TXA)
- Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage at Pre-hospital Phase of Care.CompletedPhase 1/2Banc de Sang i TeixitsNCT03780894Written as Tranexamic Acid
- Application of Iced Normal Saline Combined With Cocktail Perfusion in Total Knee ArthroplastyCompletedNot applicableYantai Yuhuangding HospitalNCT05204056Written as Tranexamic acid injection
- Combined Topical Tranexamic Acid With Floseal® in Total Knee ArthroplastyCompletedPhase 4Chang Gung Memorial HospitalNCT03328832Written as Topical tranexamic acid
- Ulipristal Use in Chinese PopulationTerminatedPhase 4Queen Mary Hospital, Hong KongNCT02825719Written as Tranexamic Acid
- Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial OsteotomyCompletedNot applicableQilu Hospital of Shandong UniversityNCT03954860Written as Tranexamic Acid
- Evaluation of the Pharmacokinetic Profile of Tranexamic Acid, After Injection in a Knee Neo-articulation.CompletedEarly Phase 1Brugmann University HospitalNCT02319915Written as Tranexamic Acid
- Reducing Blood Loss Using Tisseel in TKAStatus unknownPhase 4Chang Gung Memorial HospitalNCT03310060Written as Tranexamic Acid
- The Effects of Low-dose Epinephrine Plus Tranexamic Acid on Perioperative Haemostasis and Inflammatory Reaction in Major SurgeryStatus unknownNot applicableSouthwest Hospital, ChinaNCT02864095Written as Tranexamic acid (TXA)
- Intravenous Versus Topical Administration of Low Dose Epinephrine Plus Combined Administration of Intravenous and Topical Tranexamic Acid (TXA)for Primary Total Knee ArthroplastyStatus unknownNot applicableSouthwest Hospital, ChinaNCT02860221Written as Tranexamic acid (TXA)
- Evaluation of Intraarticular Tranexamic Acid to Reduction of Total Blood Loss Following Knee-ArthroplastyCompletedPhase 4Hvidovre University HospitalNCT02427412Written as Tranexamic Acid
- Study of DDAVP Combined With TXA on the Blood Loss and Transfusion Need During and After Scoliosis Correction SurgeryStatus unknownNot applicableLiu WeifengNCT02084342Written as tranexamic acid and sodium chloride injection
As the comparator · 16 — what is tested is compared with Tranexamic Acid
- Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH)RecruitingPhase 2/3St. Olavs HospitalNCT07245264Written as Tranexamic Acid (Cyklokapron)
- The Use of Tranexamic Acid in the Treatment of Symptomatic Subdural HematomaRecruitingPhase 3Unity Health TorontoNCT05713630Written as Tranexamic acid (TXA)
- Injectable Platelet-Rich Fibrin Versus Intradermal Tranexamic Acid for MelasmaRecruitingNot applicableKasr El Aini HospitalNCT07540702Written as Tranexamic acid 100 mg/mL (Kapron)
- Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty（TKA）RecruitingPhase 2ScinnoHub Pharmaceutical Co., Ltd.NCT07127042Written as Tranexamic Acid (IV)
- Tranexamic Acid in Pediatric Scoliosis SurgeryRecruitingNot applicableSeoul National University HospitalNCT06091891Written as Tranexamic acid
- Combined Tranexamic Acid Use in Total Hip Replacement SurgeryCompletedNot applicableSt. Anne's University Hospital Brno, Czech RepublicNCT07610863Written as Intravenous Tranexamic Acid
- Effectiveness of Oral Melatonin vs Oral Tranexamic Acid in the Treatment and Recurrence of MelasmaActive, not recruitingPhase 4Thammasat UniversityNCT07034560Written as Tranexamic Acid (TXA)
- Comparison of Chitosan, Ankaferd and Tranexamic Acid in Dental Extraction in Liver Pre-Transplant ChildrenCompletedEarly Phase 1British University In EgyptNCT06457360Written as tranexamic acid
- Effect of Prophylactic Tranexamic Acid on Bleeding Outcomes for Dilation and EvacuationCompletedPhase 2University of HawaiiNCT04651166Written as Tranexamic acid
- Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE)CompletedPhase 3ShireNCT00500656Written as Tranexamic Acid
- Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss After Total Hip ReplacementCompletedPhase 2Carlos A Acosta-OlivoNCT04187014Written as Tranexamic acid tablets
- Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in Subjects Undergoing TKATerminatedPhase 2Pacira Pharmaceuticals, IncNCT02922582Written as Tranexamic Acid
- Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacement.CompletedPhase 2Universidad Autonoma de Nuevo LeonNCT03365999Written as Oral Tranexamic Acid
- Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood LossStatus unknownPhase 3Assiut UniversityNCT03139422Written as Tranexamic Acid 500 MG
- Topical and Intravenous Administration of TXA Are Equally Effective in DAA THACompletedPhase 2Ziekenhuis Oost-LimburgNCT01940692Written as 1.5g intravenous Exacyl
- Outcomes and Safety Trial Investigating Ecallantide's Effect on Reducing Surgical Blood Loss Volume in Subjects at High Risk of Bleeding Exposed to Cardio-pulmonary Bypass During Cardiac SurgeryCompletedPhase 2Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT00888940Written as Cyklokapron(R)
Codes
What other systems call Tranexamic Acid · ClinicalTrials.gg INT008339
- MeSH (NLM) D014148Tranexamic AcidConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6T84R30KC1TRANEXAMIC ACIDConfirmed FDA, NLM, Wikidata
- RxNorm 10691Confirmed FDA, Wikidata
- Wikidata Q418666tranexamic acidConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47765Tranexamic AcidOne source FDA
- DrugBank DB00302One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014148 | Tranexamic Acid | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6T84R30KC1 | TRANEXAMIC ACID | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10691 | — | Confirmed FDA, Wikidata |
| Wikidata | Q418666 | tranexamic acid | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47765 | Tranexamic Acid | One source FDA |
| DrugBank | DB00302 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.