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Brain Concussion clinical trials

The registry lists 637 studies for Brain Concussion across more than 10 countries. 163 are recruiting or about to start. 482 of them are mainly about Brain Concussion (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Post-Concussion Syndrome too: 703 studies, 182 open.

ClinicalTrials.gov finds 765 studies for Brain Concussion. How that becomes 636 here

This page counts the studies the registry files under Brain Concussion, and those it files under no condition that list Brain Concussionthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 765Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −65Filed under a narrower condition, counted on its own pagePost-Concussion Syndrome 63
  3. −1List Brain Concussion as a condition, but the registry did not file them under itMost often written as “Minor/Mild Traumatic Brain Injury” (1). The registry filed them under other conditions only, most often Brain Injuries, Traumatic (1).
  4. −63Match it another way48 name it in the title and 15 by a synonym or other text the search reads.
  5. 636The count on this page1 of them list Brain Concussion in their own words; the registry filed them under no condition.

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Status

Completed
316
Recruiting
112
Status unknown
60
Terminated
46
Not yet recruiting
35
Active, not recruiting
27

Phase

Phase 2
38
Phase 1
23
Phase 3
12
Phase 4
5
Early Phase 1
3

Where

United States
418
Canada
79
France
26
Denmark
18
United Kingdom
8
China
6

Who runs them

VA Office of Research and Development (27) · Children's Hospital Medical Center, Cincinnati (24) · University of British Columbia (13) · University of Pittsburgh (13) · University of Calgary (13) · Seattle Children's Hospital (11) · Henry M. Jackson Foundation for the Advancement of Military Medicine (8) · BrainScope Company, Inc. (7)

What is being tested here

Drugs under test in Brain Concussion studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Creatine304
Creatine monohydrate203
Memantine212
Growth Hormone103
Amino Acids, Branched-Chain102
Human Growth Hormone122
Erenumab102
Acetaminophen102
Acetylcysteine102
Metoclopramide102

Drug classes tested here Antiemetics 1 open

Coming up

6phase 3 studies under way
63studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 112 Brain Concussion studies recruiting now, 33 (29%) set no upper age limit and 72 (64%) stop at 75 or younger. 24 (21%) take children under 18. 2 (2%) are for women only and 8 (7%) for men only; 38 (34%) take healthy volunteers.

Recruiting studies that take each age, of 112
AgeWomenMen
106 (5%)6 (5%)
1890 (80%)93 (83%)
3083 (74%)87 (78%)
4078 (70%)81 (72%)
5073 (65%)76 (68%)
6554 (48%)56 (50%)
7538 (34%)40 (36%)
8534 (30%)35 (31%)

Across all 637 studies, recruiting or not: 72% stop at 75 or younger and 67% at 65; 41% take children; 1% are for women only and 5% for men only; 39% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Brain Concussion studies take

Of 264 interventional studies with no phase under Brain Concussion, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase28 mo19–47 · 264 studies—28 mo19–47 · 248 studies
Observational35 mo16–64 · 94 studies—37 mo25–188 · 72 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting1

Results posted2

Stopped2

Newly registered7

Show 2 more

Studies

Recruiting first, then most recently updated. Showing 50 of 637. Browse all 637 → or search them.