VA Office of Research and Development: Brain Injuries, Traumatic trials

The registry lists 59 Brain Injuries, Traumatic studies with VA Office of Research and Development as lead sponsor. 7 are open to participants now and 40 have results posted.

Early Phase 1 1Phase 1 3Phase 2 2Phase 3 1Phase 4 2No phase 50(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• hCG Treatment for Rehabilitation From a TBINot yet recruitingNCT07557615Early Phase 1
• Behavior Therapy vs Education for Persistent Headache After Mild TBINot yet recruitingNCT07229391Not applicable
• Improving Sleep in Veterans With the Polytrauma Clinical TriadRecruitingNCT06477796Not applicable
• Methylphenidate for the Treatment of PTSD With Associated Neurocognitive ComplaintsRecruitingNCT05776056Phase 4
• Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain InjuryRecruitingNCT05647044Phase 1
• Allopregnanolone in Chronic Complex Traumatic Brain InjuryNot yet recruitingNCT04003285Phase 2
• Mild TBI Assessment & RehabilitationRecruitingNCT02920788Not applicable
• The Feasibility of Home-Based Measurement of Circadian Timing for Veterans With TBI and InsomniaCompletedNCT05665764Results posted
• ACTIVE: Activity Therapy to Increase Veteran EngagementCompletedNCT04976621Not applicableResults posted
• SmART-TBI: Supplementation With Amino Acid Rehabilitative Therapy in TBICompletedNCT04603443Not applicableResults posted
• Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic PainCompletedNCT04517604Not applicableResults posted
• Feasibility of Improving Sleep Apnea Treatment Adherence After Brain InjuryCompletedNCT04221009Not applicableResults posted
• One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of ChangeCompletedNCT04143243Not applicableResults posted
• Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBICompletedNCT04044456Not applicableResults posted
• Remotely Supervised tDCS for Persistent Post-traumatic HeadacheCompletedNCT04012853Not applicableResults posted
• Neuroplasticity in TBI and SchizophreniaCompletedNCT03995368Not applicableResults posted
• Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration WorkshopCompletedNCT03868930Not applicableResults posted
• Improving Sleep in Veterans With TBICompletedNCT03785600Not applicableResults posted
• Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of LifeCompletedNCT03615222Results posted
• Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health CareCompletedNCT03539068Not applicableResults posted
• Brain Markers of Improvements in Cognitive FunctioningCompletedNCT03490110Not applicableResults posted
• Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic StimulationCompletedNCT03314584Not applicableResults posted
• Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSDCompletedNCT03283163Not applicableResults posted
• Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain InjuryCompletedNCT03261674Not applicableResults posted
• Transcranial Electrical Stimulation for mTBICompletedNCT03244475Not applicableResults posted
• One-Day Life Skills Workshop for Veterans With TBI, Pain and PsychopathologyCompletedNCT02844946Not applicableResults posted
• Biological Signatures, Probiotic Among Those With mTBI and PTSDCompletedNCT02723344Phase 1Results posted
• Cognitive-Behavioral Therapy for Veterans With TBICompletedNCT02658669Not applicableResults posted
• Informal Caregivers ANSWERS-VACompletedNCT02398409Not applicableResults posted
• Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSDCompletedNCT02391402Not applicableResults posted
• rTMS to Improve Cognitive Function in TBICompletedNCT02152540Not applicableResults posted
• Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBICompletedNCT02057081Not applicableResults posted
• Simvastatin for mTBICompletedNCT01952288Phase 4Results posted
• Improving Functions in MTBI Patients With Headache by rTMSCompletedNCT01948947Not applicableResults posted
• Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBICompletedNCT01921179Not applicableResults posted
• Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASSCompletedNCT01816061Not applicableResults posted
• Rivastigmine Patch in Veterans With Cognitive Impairment Following TBICompletedNCT01670526Phase 3Results posted
• Neuroactive Steroids and Traumatic Brain Injury (TBI) in OEF/OIF VeteransCompletedNCT01336413Phase 2Results posted
• AcuSleep in Mild Traumatic Brain Injury (TBI)CompletedNCT01162317Not applicableResults posted
• Top-Down Executive Control in Traumatic Brain Injury (TBI), PTSD and CombinedCompletedNCT01072006Results posted
• Quantitative Automated Lesion Detection of Traumatic Brain InjuryCompletedNCT01022307Results posted
• Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)CompletedNCT01021137Results posted
• Eye Movement Recordings in the Diagnosis of Traumatic Brain InjuryCompletedNCT00875589Results posted
• Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)CompletedNCT00714571Phase 1Results posted
• Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain InjuryCompletedNCT00676182Results posted
• The Efficacy of Familiar Voice Stimulation During Coma RecoveryCompletedNCT00557076Not applicableResults posted
• Central Auditory Processing Disorders Associated With Blast ExposureCompletedNCT00554801Not applicableResults posted
• Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain InjuryWithdrawnNCT06380985Not applicable
• Balance After Traumatic Brain InjuryCompletedNCT05714150Not applicable
• Foundations in Developing Precision Cognitive RestorationWithdrawnNCT05117502Not applicable
• Narrative Discourse Treatment DevelopmentCompletedNCT05008419Not applicable
• Vagal Nerve Stimulation in mTBICompletedNCT04437498Not applicable
• GOALS Cognitive Training Delivered to Aging Veterans in Person or Via TelehealthCompletedNCT04111549Not applicable
• Cognitive Rehabilitation and Brain Activity of Attention Control in TBIWithdrawnNCT02589509Not applicable
• LED Treatment to Improve Cognition and Promote Recovery in TBICompletedNCT02404402Not applicable
• LED Light Therapy to Improve Cognitive & Psychosocial Function in TBI-PTSD VeteransWithdrawnNCT02356861Not applicable
• Developing Process-Specific Verbal Memory Interventions for Veterans With Tramatic Brain Injury (TBI)CompletedNCT02310633Not applicable
• Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)CompletedNCT01138020Not applicable
• Awareness of Deficit After Combat-related Brain InjuryCompletedNCT00478400