Chronic Traumatic Encephalopathy clinical trials
The registry lists 27 studies for Chronic Traumatic Encephalopathy across more than 10 countries. 11 are recruiting or about to start. 14 of them are mainly about Chronic Traumatic Encephalopathy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Status
Who runs them
University Hospital, Strasbourg, France (4) · MD Stem Cells (2) · Boston University (2) · University of California, Los Angeles (2) · Macquarie University, Australia (1) · Tianjin Medical University (1) · Samuel Gandy (1) · OMNI Medical Services, LLC (1)
What is being tested here
Drugs under test in Chronic Traumatic Encephalopathy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Medical Marijuana | 1 | 0 | 1 |
| Flortaucipir | 0 | 0 | 2 |
| Fish Oils | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD) · VA Office of Research and Development
- Mar 2027A Prospective Study of Cognitive Changes in Retired and Late-Career Professional Soccer Players · University Hospital, Strasbourg, France
- Jun 2027Cerebral and Cognitive Impact of Female Professional SoccerPractice · University Hospital, Strasbourg, France
- Jul 2027Neurologic Stem Cell Treatment Study · MD Stem Cells
Who these studies take
Of the 8 Chronic Traumatic Encephalopathy studies recruiting now, 3 (38%) set no upper age limit and 3 (38%) stop at 75 or younger. 1 (13%) take children under 18. 1 (13%) are for women only and 3 (38%) for men only; 6 (75%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (13%) | 1 (13%) |
| 18 | 2 (25%) | 2 (25%) |
| 30 | 3 (38%) | 4 (50%) |
| 40 | 4 (50%) | 6 (75%) |
| 50 | 5 (63%) | 7 (88%) |
| 65 | 5 (63%) | 5 (63%) |
| 75 | 4 (50%) | 5 (63%) |
| 85 | 4 (50%) | 5 (63%) |
Across all 27 studies, recruiting or not: 26% stop at 75 or younger and 15% at 65; 7% take children; 7% are for women only and 37% for men only; 56% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 27 of 27. search them.
- A Prospective Study of Cognitive Changes in Retired and Late-Career Professional Soccer PlayersNot yet recruitingNCT07910994
- Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)RecruitingNCT041240291 country
- Cerebral and Cognitive Impact of Female Professional SoccerPracticeRecruitingNCT06788262Not applicable1 country
- Neurologic Stem Cell Treatment StudyRecruitingNCT02795052Not applicable2 countries
- The DIAGNOSE CTE Research Project-IIEnrolling by invitationNCT068608281 country
- Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic LesionsRecruitingNCT073025031 country
- Cerebral and Cognitive Impact of Professional Soccer PracticeRecruitingNCT04903015Not applicable1 country
- Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's DiseaseRecruitingNCT06254469Phase 31 country
- Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment StudyEnrolling by invitationNCT03724136Not applicable2 countries
- Outcomes Mandate National Integration With Cannabis as MedicineRecruitingNCT03944447Phase 21 country
- Post-Concussion Syndrome in Professional Athletes: A Multidisciplinary StudyRecruitingNCT032183321 country
- Cohort Study of Blood Biomarkers for TESCompletedNCT049285341 country
- Heading in Football: Impact on Neural Blood BiomarkersCompletedNCT061475961 country
- The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football AthletesCompletedNCT04796207Not applicable1 country
- Tau And Connectomics In TES StudyActive, not recruitingNCT05490576Phase 11 country
- The DIAGNOSE-CTE Research ProjectCompletedNCT027981851 country
- Near-Infrared Laser Stimulation for Various Neurological ConditionsStatus unknownNCT04489082Not applicable1 country
- Long-term Follow-up in Severe Traumatic Brain InjuryStatus unknownNCT052358021 country
- FDDNP Protocol for Visualizing Brain Proteinopathies to Assist in the Diagnosis of Persons With Suspected CTE and ADWithdrawnNCT04311281
- Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain SyndromeCompletedNCT02957123Phase 1/21 country
- 18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic EncephalopathyCompletedNCT02079766Phase 21 country
- Traumatic Brain Injury and Risk for Chronic Traumatic EncephalopathyCompletedNCT020031831 country
- Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain InjuryCompletedNCT022665631 country
- Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military PersonnelWithdrawnNCT018913831 country
- Tau Imaging of Chronic Traumatic EncephalopathyCompletedNCT02191267Phase 21 country
- Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented TreadmillCompletedNCT014133211 country
- Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy SubjectsCompletedNCT02103894Phase 11 country