Drug class
Central Nervous System Stimulants clinical trials
A class of medicines: the studies that test any of its 17 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Keep track of what changes. Save the central nervous system stimulants studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesMedicines in this class
Studies that test each. A study of two counts under both, and once above.
- Serdexmethylphenidate and dexmethylphenidate
- 2
- Pemoline
- 2
- Phendimetrazine
- 1
Studies by the year they started
1,045 studies that test it; most in 2014 (58); 1 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 3 |
| 1995 | 2 |
| 1996 | 1 |
| 1997 | 4 |
| 1998 | 5 |
| 1999 | 6 |
| 2000 | 4 |
| 2001 | 10 |
| 2002 | 15 |
| 2003 | 31 |
| 2004 | 35 |
| 2005 | 33 |
| 2006 | 49 |
| 2007 | 49 |
| 2008 | 55 |
| 2009 | 49 |
| 2010 | 51 |
| 2011 | 45 |
| 2012 | 46 |
| 2013 | 46 |
| 2014 | 58 |
| 2015 | 26 |
| 2016 | 45 |
| 2017 | 31 |
| 2018 | 47 |
| 2019 | 42 |
| 2020 | 26 |
| 2021 | 24 |
| 2022 | 28 |
| 2023 | 50 |
| 2024 | 44 |
| 2025 | 35 |
| 2026 | 50 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 246 · Other 807
Shire (46) · Cephalon (27) · Massachusetts General Hospital (23) · New York State Psychiatric Institute (18) · M.D. Anderson Cancer Center (16) · National Institute on Drug Abuse (NIDA) (14) · University of Chicago (13) · VIVUS LLC (12)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten.
Testing one of them · 1,053
- CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)Not yet recruitingPhase 2University of AlbertaNCT06972108Written as Caffeine citrate
- Efficacy and Safety of Modafinil to Treat Fatigue in People With Mitochondrial Disease.Not yet recruitingPhase 3Kenneth Myers, MDNCT07887412Written as Modafinil (M)
- Oxygen Toxicity: Mechanisms in HumansRecruitingNot applicableDuke UniversityNCT05761756Written as Caffeine
- Norepinephrine With Ephedrine Versus Norepinephrine Alone During Spinal Anesthesia for Cesarean DeliveryRecruitingPhase 4Cairo UniversityNCT07379710Written as Ephedrine and Norepinephrine infusion
- Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric SurgeryRecruitingPhase 4University of California, IrvineNCT05975580Written as Phentermine
- Acute Effects of Caffeine on Mitochondrial Function in Peripheral Blood Mononuclear CellsNot yet recruitingNot applicablePontificia Universidad Catolica de ChileNCT07873047Written as Caffeine (5 mg/kg)
- DDI Study of ECC0509 With Metformin, Midazolam, and CaffeineNot yet recruitingPhase 1EccogeneNCT07873229Written as Caffeine
- Phentermine's Impact on Treatment in TeensRecruitingPhase 2Russell McCulloh, MDNCT07282340Written as Phentermine
- Evaluation of Foquest in Adults 65 Years and Older With ADHDRecruitingPhase 4Dar Clinical Research Inc.NCT07710014Written as Methylphenidate hydrochloride extended-release capsules
- Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill RunRecruitingNot applicableSt. Louis UniversityNCT07854223Written as Caffeine
- Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder and Cannabis Use DisorderNot yet recruitingPhase 4Massachusetts General HospitalNCT07838311Written as Delayed-release, extended-release methylphenidate
- Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity DisorderRecruitingPhase 4Donald Gilbert, MD, MS, FAAN, FAAPNCT04421248Written as Methylphenidate
- Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and LymphomaNot yet recruitingPhase 2St. Jude Children's Research HospitalNCT07790913Written as Phentermine/Topiramate ER
- Benefits of ADHD Treatment in Detained PeopleRecruitingPhase 3Stéphanie BaggioNCT05842330Written as Concerta
- Modafinil to Optimize the Performance of Cold-Stressed Sleep-Deprived PersonnelRecruitingPhase 4United States Army Research Institute of Environmental MedicineNCT07830056Written as Modafinil (M)
- Placebo Effect on Cycling Performance: Laboratory Crossover StudyNot yet recruitingNot applicablePoznan University of Physical EducationNCT07748429Written as Caffeine (6mg/kg)
- Improving Preterm Kidney Outcomes With CaffeineRecruitingPhase 2University of Wisconsin, MadisonNCT07262060Written as Caffeine citrate
- Treating Young Children With Attention Deficit Hyperactivity DisorderRecruitingPhase 4Children's Hospital Medical Center, CincinnatiNCT07300956Written as Methylphenidate (MPH)
- Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)RecruitingPhase 2/3Radboud University Medical CenterNCT07582458Written as Modafinil
- Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell DiseaseRecruitingPhase 1St. Jude Children's Research HospitalNCT07226219Written as Extended-Release Methylphenidate
See all 1,053 studies that test one of the central nervous system stimulants →
Codes
What other systems call Central Nervous System Stimulants · ClinicalTrials.gg INT006970
- MeSH (NLM) D000697Central Nervous System StimulantsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000697 | Central Nervous System Stimulants | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.