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Smoking clinical trials

The registry lists 1,509 studies for Smoking across more than 10 countries. 193 are recruiting or about to start. 671 of them are mainly about Smoking (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 6 narrower conditions too, such as Cigarette Smoking: 2,330 studies, 362 open.

ClinicalTrials.gov finds 3,914 studies for Smoking. How that becomes 1,509 here

This page counts the studies the registry files under Smoking, and those it files under no condition that list Smokingthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,914Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −810Filed under a narrower condition, counted on its own pageVaping 317 · Cigarette Smoking 267 · Tobacco Smoking 123 · Smoking Reduction 21 · Marijuana Smoking 19 · Water Pipe Smoking 17
  3. −821List Smoking as a condition, but the registry did not file them under itMost often written as “Smoking Cessation” (769), “Smoking Cessation; Tobacco Dependence” (5), and “Smoking Status” (4). The registry filed 9 of them under no condition at all, and the others under other conditions only, most often Smoking Cessation (787) and Tobacco Use Disorder (67).
  4. −774Match it another way592 name it in the title, 121 in a keyword, and 61 by a synonym or other text the search reads.
  5. 1,509The count on this page31 of them list Smoking in their own words; the registry filed them under no condition.

Get an email when these change. Save the Smoking studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
1,069
Recruiting
140
Status unknown
110
Terminated
58
Not yet recruiting
43
Active, not recruiting
40

Phase

Phase 2
138
Phase 4
95
Phase 1
91
Phase 3
81
Early Phase 1
20

Where

United States
898
Turkey
71
Canada
49
United Kingdom
37
France
36
Spain
27

Who runs them

Yale University (49) · RAI Services Company (45) · Philip Morris Products S.A. (35) · University of Wisconsin, Madison (33) · Medical University of South Carolina (30) · Duke University (30) · The University of Hong Kong (29) · University of Minnesota (26)

What is being tested here

Drugs under test in Smoking studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Semaglutide202
Bupropion1822
Nicotine Lozenge105
Cycloserine104
Progesterone102
Aspirin102
Daridorexant101
Ethanol101
Dextromethorphan/Bupropion Tablet AXS-05111
Fisetin101

Drug classes tested here GLP-1 receptor agonists 3 open · NSAIDs 1 open · Opioid antagonists 11 · Cholinesterase inhibitors 5 · Bronchodilators 5

Coming up

5phase 3 studies under way
83studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 140 Smoking studies recruiting now, 74 (53%) set no upper age limit and 48 (34%) stop at 75 or younger. 3 (2%) take children under 18. 4 (3%) are for women only and 4 (3%) for men only; 65 (46%) take healthy volunteers.

Recruiting studies that take each age, of 140
AgeWomenMen
101 (1%)1 (1%)
1886 (61%)87 (62%)
30123 (88%)123 (88%)
40124 (89%)124 (89%)
50126 (90%)127 (91%)
65111 (79%)112 (80%)
7597 (69%)96 (69%)
8582 (59%)81 (58%)

Across all 1,509 studies, recruiting or not: 47% stop at 75 or younger and 38% at 65; 10% take children; 5% are for women only and 3% for men only; 55% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Smoking studies take

Of 34 phase 1 interventional studies under Smoking, half reached primary completion within 36 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 136 mo16–49 · 34 studies—40 mo20–51 · 31 studies
Phase 235 mo17–62 · 22 studies——
Phase 326 mo16–42 · 14 studies——
Phase 435 mo18–71 · 29 studies—35 mo18–71 · 29 studies
Interventional, no phase23 mo8–40 · 456 studies3 mo1–6 · 55 studies26 mo12–42 · 401 studies
Observational38 mo17–103 · 89 studies—42 mo19–114 · 82 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting2

Results posted3

Newly registered9

Show 4 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,509. Browse all 1,509 → or search them.