Smoking clinical trials
The registry lists 266 studies for Smoking across more than 10 countries. 135 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Recruiting
- 98
- Completed
- 96
- Not yet recruiting
- 31
- Active, not recruiting
- 28
- Enrolling by invitation
- 6
- Terminated
- 5
Phase
- Phase 2
- 20
- Phase 4
- 10
- Phase 1
- 8
- Early Phase 1
- 5
- Phase 3
- 5
Where
- United States
- 163
- Turkey (Türkiye)
- 30
- Germany
- 5
- France
- 5
- Canada
- 5
- Poland
- 4
Who runs them
RAI Services Company (11) · Medical University of South Carolina (9) · VA Office of Research and Development (8) · University of Minnesota (7) · Massachusetts General Hospital (7) · Abramson Cancer Center at Penn Medicine (6) · Wake Forest University Health Sciences (5) · M.D. Anderson Cancer Center (5)
Studies
Recruiting first, then most recently updated. Showing 50 of 266 — search for more.
- Using Smartwatches to Monitor Smoking in Real-life SituationsEnrolling by invitationNCT070671511 country
- Smartphone-based Incentives Intervention to Increase Smoking Cessation During PregnancyNot yet recruitingNCT07840118Not applicable1 country
- A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid RelapseRecruitingNCT07223840Phase 23 countries
- Semaglutide for Post-Smoking Cessation Weight ManagementRecruitingNCT06173778Phase 21 country
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)RecruitingNCT07711691Not applicable1 country
- Actívatexto: Advancing Smoking Cessation and Physical Activity Among LatinosRecruitingNCT06926608Not applicable1 country
- Integrated Healthy Lifestyle and Pain Care for People With Musculoskeletal Conditions Living in Rural Areas.RecruitingNCT07173335Not applicable1 country
- Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation TreatmentEnrolling by invitationNCT05627674Not applicable1 country
- QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)Not yet recruitingNCT07661823Not applicable1 country
- Impact of Smoking on Immune Responses in Peri-implant Health and DiseaseRecruitingNCT077501711 country
- SMOKING AND GINGIVAL CREVICULAR FLUID MFN1 AND NLRP3 LEVELS IN PERIODONTAL HEALTH AND PERIODONTITISRecruitingNCT078267281 country
- Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)RecruitingNCT05276050Not applicable1 country
- Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)RecruitingNCT07145866Phase 41 country
- C-Raven LDCT: Lung Cancer Screening InterventionNot yet recruitingNCT07819318Not applicable
- Overcoming Nicotine Dependence to Enable QuittingRecruitingNCT05513872Phase 1/21 country
- Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)RecruitingNCT07766655Phase 31 country
- Impact of Lifestyle on Health Maintenance: A Randomized Controlled TrialNot yet recruitingNCT07314957Not applicable1 country
- Vaped PhenanthreneRecruitingNCT07134426Not applicable1 country
- Pain and Smoking Study 2Not yet recruitingNCT06442514Not applicable1 country
- Pancreatic Cancer Lifestyle Evolution And ResistanceNot yet recruitingNCT07794969
- Nicotinic Receptor Genetic Variation and Alcohol RewardRecruitingNCT03294460Phase 11 country
- Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit SmokingNot yet recruitingNCT07789132Not applicable1 country
- A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free HomeRecruitingNCT06693700Not applicable1 country
- Efficacy of the Proactive Automatized Lifestyle InterventionRecruitingNCT07441603Not applicable1 country
- DoubleTake: Effect of Message Exposure Via a Discrete Choice Experiment With Eye-Tracking on Quit Attempts Among Adults Who Smoke Menthol CigarettesNot yet recruitingNCT07782879Not applicable1 country
- Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRPRecruitingNCT065527411 country
- Evaluation of Low and High Nicotine Tobacco Free Nicotine PouchesRecruitingNCT06678789Not applicable1 country
- A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking CessationRecruitingNCT07487818Phase 2/31 country
- Negative Pressure Wound Therapy Devices in Total Knee ArthroplastyNot yet recruitingNCT07770633Not applicable
- A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science ResearchEnrolling by invitationNCT05852860Not applicable1 country
- A Clinical Trial of Adaptive Treatment for Early Smoking Cessation RelapseRecruitingNCT06118502Not applicable1 country
- The Effect of Motivational Interviewing on Smoking Behavior Among Nursing StudentsNot yet recruitingNCT07758998Not applicable1 country
- DOSE-UP: Dose Optimization for Smoking and E-Cigarette Use PharmacotherapyNot yet recruitingNCT07754578Phase 21 country
- Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care NetworkRecruitingNCT06582693Not applicable1 country
- Just-in-Time Support for Smoking, Vaping, and Eating Urges During High-Stress Moments Among Gender and Sexual Minority Adults in DhakaNot yet recruitingNCT07746492Not applicable1 country
- Personalized Tobacco Treatment in Primary Care (MOTIVATE)RecruitingNCT05846841Not applicable1 country
- A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System ProductsNot yet recruitingNCT07739797Not applicable
- Precision Treatment to Promote Smoking Cessation and Survival in Oncology PatientsRecruitingNCT07166120Not applicable1 country
- Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the EnvironmentRecruitingNCT07089901Phase 41 country
- Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol CigarettesRecruitingNCT05896033Not applicable1 country
- Bayesian Neurobehavioral Phenotyping: From Mechanism Identification to Personalized Neuromodulation Treatments. R61 PHASERecruitingNCT06991062Not applicable1 country
- Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing HomelessnessNot yet recruitingNCT07714200Not applicable1 country
- A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette SmokersRecruitingNCT07710820Not applicable1 country
- Multi-Site Trial of Tirzepatide for Smoking CessationRecruitingNCT07602699Phase 21 country
- Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and ChildrenRecruitingNCT04783857Phase 41 country
- Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54RecruitingNCT04577599Not applicable1 country
- Switch or Quit R01RecruitingNCT06373679Not applicable1 country
- Enhancing Smoking Cessation for African American People EverywhereRecruitingNCT07024992Phase 21 country
- Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch UseRecruitingNCT07698470Not applicable1 country
- Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting SmokingRecruitingNCT07459621Not applicable1 country