An observational study in Peri-Implant Health, Peri Implant Mucositis and Peri-implantitis, sponsored by Gazi University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 21 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Gazi University · Observational
Among 52 studies in Peri-Implantitis with a site in Turkey — 14 open to participants now, 17 under way, none of them phase 3. Peri-Implantitis · Turkey.
Among the 52 studies in Peri-Implantitis with a site in Turkey, this one is the 3rd largest by planned enrollment of the 28 observational ones, is one of 8 that started in 2026, is one of 28 observational ones, reaches primary completion later than 7 of the 16 other live ones, and was the 48th registered.
322 studies on the registry are indexed under Peri-Implantitis; 88 are open to participants now.
This study's planned enrollment of 216 is above the median of 83 across 121 observational studies indexed under Peri-Implantitis.
Browse Peri-Implantitis studies →14 of the 52 studies in Peri-Implantitis with a site in Turkey are open now, in 1 country. Each count lists the studies.
Of the 48 Peri-Implantitis studies recruiting now, 26 (54%) set no upper age limit and 9 (19%) stop at 75 or younger; 7 take children under 18; 25 take healthy volunteers.
This study: 21 Years to 75 Years · all sexes · healthy volunteers too.
The full table on the hub →52 studies; the count open now beside each. This study's row is marked.
First in 2010; this study’s year is marked. 8 started in 2026.
Median enrollment 50 across the 24 interventional studies, 84 across the 28 observational. Of the 33 that completed or were terminated, 1 (3%) have results posted.
None of the 52 has an industry lead sponsor. The 10 most frequent:
Gazi University is the lead sponsor of 551 studies on the registry; 102 are open to participants now.
Gazi University has 6 studies filed under Peri-Implantitis — fewer than ten, so there is no comparison to draw.
6 of the studies in Peri-Implantitis with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06830200Hacettepe UniversityPeri-implantitis Treatment With Chitosan Brush | 2026-12-01 |
| NCT07907900Ankara UniversityDiagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs | 2026-12-31 |
| NCT07785817Medipol UniversityEvaluation of aMMP-8 and IL-1β Levels and Marginal Bone Loss Associated With Peri-Implant Mucositis and Peri-Implantitis in Postmenopausal Women | 2027-02-01 |
| NCT07797127Adiyaman UniversityEvaluation of the Effects of Routine Phase I Periodontal Therapy on Clinical Parameters and Levels of Gremlin-1, CTHRC1, and Tenascin-C in Gingival Crevicular Fluid and Peri-Implant Sulcular Fluid in Individuals With Periodontitis and Peri-Implantitis | 2027-03-01 |
| NCT07471386Gazi UniversityAdjunctive Keratinized Mucosa Augmentation in Peri-Implantitis | 2027-04-01 |
Among the 52 studies in Peri-Implantitis with a site in Turkey, from their registry updates:
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases, implant failure. Smoking is an important risk factor for these conditions because it may change how the immune system responds to inflammation and infection.
This study will compare smokers and non-smokers with healthy dental implants, peri-implant mucositis, or peri-implantitis. Fluid samples will be collected from around the implants to measure proteins involved in inflammation, healing, and immune responses. The aim is to better understand how smoking affects the body's response to peri-implant diseases and to identify biological markers that may help assess disease risk and severity in the future.
The study population will consist of adults with at least one dental implant who attend the Department of Periodontology at Gazi University Faculty of Dentistry. Eligible participants will be classified as smokers or non-smokers and further assigned to one of three groups according to their peri-implant condition: peri-implant health, peri-implant mucositis, or peri-implantitis. Participants will be consecutively recruited until the target sample size is reached.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants who do not smoke and have clinically healthy peri-implant tissues.
Participants who do not smoke and have peri-implant mucositis.
Participants who do not smoke and have peri-implantitis.
Participants who smoke and have clinically healthy peri-implant tissues.
Participants who smoke and have peri-implant mucositis.
Participants who smoke and have peri-implantitis
Peri-implant crevicular fluid levels of Th1/Th2-, M1/M2-, and B-cell-related immune markers
Peri-implant crevicular fluid samples will be analyzed to determine the levels of IFN-γ, IL-12p70, IL-4, IL-13, IL-10, BAFF, and APRIL. These marker levels will be compared among smokers and non-smokers with peri-implant health, peri-implant mucositis, or peri-implantitis
Time frame: At a single study visit
Plan to share: Undecided
No publications or documents are linked to this record.
Started Jun 2026 (actual). Primary completion is estimated for Oct 2026, 4 months after the start.
How these figures are worked out, and which studies are left out of them.
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Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
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