Smoking Reduction clinical trials
The registry lists 21 studies for Smoking Reduction across 7 countries. 11 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-10-22.
Keep track of what changes. Save the Smoking Reduction studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesWho runs them
University of California, San Francisco (1) · University of Kansas Medical Center (1) · VA Office of Research and Development (1) · University of Arizona (1) · Peking Union Medical College (1) · Memorial Sloan Kettering Cancer Center (1) · University of Oregon (1) · Insel Gruppe AG, University Hospital Bern (1)
Who these studies take
Of the 11 Smoking Reduction studies recruiting now, 7 (64%) set no upper age limit and 4 (36%) stop at 75 or younger. 1 (9%) take children under 18. 2 (18%) are for women only and 0 (0%) for men only; 7 (64%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (45%) | 3 (27%) |
| 30 | 10 (91%) | 8 (73%) |
| 40 | 10 (91%) | 8 (73%) |
| 50 | 9 (82%) | 8 (73%) |
| 65 | 8 (73%) | 7 (64%) |
| 75 | 8 (73%) | 7 (64%) |
| 85 | 7 (64%) | 6 (55%) |
Across all 21 studies, recruiting or not: 33% stop at 75 or younger and 24% at 65; 10% take children; 14% are for women only and 0% for men only; 62% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 21 of 21. search them.
- The Impact of Menthol Flavoring on Switching in Adult Menthol SmokersRecruitingNCT05555069Not applicable1 country
- Switching to E-cigarettes in Smokers Not Interested in QuittingRecruitingNCT05703672Phase 31 country
- Interventional Study on Smoking Reduction in PsychiatryRecruitingNCT06926153Not applicable3 countries
- Trauma-Informed Care for Smoking Cessation for PregnancyRecruitingNCT07129590Not applicable1 country
- Varenicline for Smoking Reduction in Veterans Not Ready To QuitRecruitingNCT06966362Phase 41 country
- A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free HomeRecruitingNCT06693700Not applicable1 country
- Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and ChildrenRecruitingNCT04783857Phase 41 country
- Early Life Intervention in Pediatrics Supported by E-health - SMOKERecruitingNCT06311162Not applicable1 country
- Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in AppalachiaRecruitingNCT05660525Not applicable1 country
- E-Cigarettes for Harm Reduction in Smokers With Opioid Use DisorderRecruitingNCT05722561Phase 21 country
- A First in Human Single Ascending Dose (SAD) Study of ATI-1013 in Healthy SmokersRecruitingNCT07215923Phase 11 country
- The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy EvaluationCompletedNCT055541201 country
- Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation InterventionCompletedNCT05277831Not applicable1 country
- Construal Level as a Novel Pathway for Affect Regulation and Cancer ControlCompletedNCT04620915Not applicable1 country
- Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking CessationCompletedNCT03083353Early Phase 11 country
- Impact of Multi-Component Interventions on High-Risk COPD SmokersCompletedNCT06458205Not applicable1 country
- Preoperative Smoking Cessation in Patients Undergoing SurgeryTerminatedNCT05192837Not applicable1 country
- Tobacco Cessation in Public HousingCompletedNCT04889638Not applicable1 country
- Supporting Smoke-Free Policy Compliance in Public HousingCompletedNCT05016505Not applicable1 country
- Combining Varenicline and Bupropion for Smoking CessationCompletedNCT00943618Phase 31 country
- BABY STEPS II: SMS Scheduled Gradual Reduction Text Messages to Help Pregnant Smokers QuitCompletedNCT01995097Not applicable1 country