Drug
Progesterone clinical trials
Also written Prometrium and Utrogestan.
Includes 10 studies of Utrogestan.
- studies test it
- 265
- open now
- 33
- in phase 3
- 47
- first study started
- 1994
Keep track of what changes. Save the Progesterone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
263 studies that test it; most in 2019 (19); 1 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1996 | 1 |
| 1999 | 1 |
| 2000 | 2 |
| 2002 | 3 |
| 2003 | 3 |
| 2004 | 8 |
| 2005 | 7 |
| 2006 | 10 |
| 2007 | 8 |
| 2008 | 11 |
| 2009 | 11 |
| 2010 | 9 |
| 2011 | 11 |
| 2012 | 14 |
| 2013 | 13 |
| 2014 | 12 |
| 2015 | 15 |
| 2016 | 15 |
| 2017 | 15 |
| 2018 | 11 |
| 2019 | 19 |
| 2020 | 13 |
| 2021 | 8 |
| 2022 | 11 |
| 2023 | 7 |
| 2024 | 1 |
| 2025 | 12 |
| 2026 | 11 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 10
- Phase 1
- 27
- Phase 2
- 52
- Phase 3
- 47
- Phase 4
- 74
- No phase
- 67
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 31 · Other 234
University of Virginia (10) · University of North Carolina, Chapel Hill (8) · IBSA Institut Biochimique SA (7) · Yale University (7) · University of Minnesota (7) · Ain Shams University (5) · Assiut University (4) · Universitair Ziekenhuis Brussel (4)
Often tested with
Tested in the same studies.
Estradiol (41) · Dydrogesterone (6) · Chorionic Gonadotropin (6) · Leuprolide (4) · Progesterone Vaginal Insert (4) · Testosterone (3) · 17 alpha-Hydroxyprogesterone Caproate (3) · Nafarelin (3)
Studies
Open first, then newest update. How each study uses Progesterone is read from its arms, and is right about nine times in ten.
Testing it · 265
- Hormone Replacement Therapy in Adolescents With Premature Ovarian InsufficiencyRecruitingPhase 3Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT06851754Written as Progesterone
- Cycle-to-cycle Variability of Progesterone in the Endometrium in Patients Undergoing an Euploid Blastocyst Transfer in a Hormone Replacement Therapy (HRT) Cycle (PROMICOFET)Not yet recruitingPhase 4University Hospital, GhentNCT07818278Written as Progesterone 200 mg vaginal capsules
- First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase InsufficiencyRecruitingPhase 1Calla Lily Clinical Care LtdNCT07136922Written as Cyclogest 400 mg
- Efficacy of Progesterone and Low Molecular Weight Heparin in Recurrent MiscarriagesNot yet recruitingPhase 3General University Hospital, PragueNCT07796737Written as Vaginal micronized progesterone
- Progesterone Supplementation After Letrozole-stimulated InseminationRecruitingPhase 4Kirstine KirkegaardNCT07508657Written as Progesterone
- Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner SyndromeRecruitingPhase 4Children's Mercy Hospital Kansas CityNCT06834594Written as Micronized progesterone 200 MG
- Progesterone Luteal Support in Unexplained Infertility ManagementNot yet recruitingPhase 3Simone BroerNCT07738068Written as Utrogestan® 200 mg Soft Capsule
- Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and ChildrenRecruitingPhase 4University of MinnesotaNCT04783857Written as Progesterone 200 MG Oral Capsule
- Prolonged Progesterone to Prevent Preterm Birth From IVF - ETRecruitingPhase 4Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT05787509Written as Progesterone Sustained-release vaginal gel
- Exogenous Progesterone as Ovulation TriggerNot yet recruitingPhase 4Instituto Valenciano de Infertilidade de LisboaNCT07466199Written as Vaginal micronized progesterone
- Individualized Prolonged Luteal Support After Fresh Embryo Transfer in Women With Low ProgesteroneNot yet recruitingPhase 3University Hospital, MontpellierNCT07613528Written as Progesterone Injectable
- Menopausal HT for Women Living With HIV (HoT)RecruitingPhase 4Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT06856174Written as Micronized Progesterone
- Comparing the Pharmacokinetics of a Progesterone Ring Versus a Progesterone Vaginal InsertNot yet recruitingPhase 1Daré Bioscience, Inc.NCT06668896Written as Progesterone
- Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNot applicableEnhanced Emirates LimitedNCT07568574Written as Progesterone Cream
- Examining the Effects of Estradiol on Neural and Molecular Response to RewardRecruitingPhase 4University of North Carolina, Chapel HillNCT05282277Written as Micronized Progesterone
- MIcronized PROgesterone in Frozen Embryo Transfer CyclesRecruitingPhase 3Fundación Santiago Dexeus FontNCT05899010Written as Vaginal progesterone 600mg daily
- Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone TherapyNot yet recruitingNot applicableSehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research HospitalNCT07496294Written as Micronized progesterone 200 MG
- Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH TreatmentRecruitingPhase 4UMC UtrechtNCT05080569Written as Progesterone Vaginal Product
- Progesterone in Gender Affirming Hormone Therapy StudyRecruitingPhase 2Emory UniversityNCT06807580Written as Progesterone
- Estrogen Supplementation and Bone Health in Women With CFRecruitingPhase 4Johns Hopkins UniversityNCT05704036Written as Progesterone
See all 265 studies that test Progesterone →
Given in every arm · 46 — Progesterone is usual care beside what is tested
- FET-LET-2x2: Clinical Pregnancy Rates After Frozen Embryo Transfer in Natural and Modified Natural CyclesRecruitingNot applicableUniversity of Novi SadNCT07425990Written as Progesterone
- A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA)RecruitingPhase 3Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, GermanyNCT07340827Written as Progesterone gel
- Azithromycin for Cerclage ProphylaxisNot yet recruitingPhase 4Wake Forest University Health SciencesNCT07608562Written as Progesterone
- LATe Cerclage in High-risk Pregnancies (LATCH)RecruitingNot applicableThomas Jefferson UniversityNCT06036446Written as Vaginal Suppository Progesterone
- A Combination of Antibiotics to Decrease Neonatal Morbidity and Mortality for Previable Threatened LaborNot yet recruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT06572761Written as Vaginal progesterone
- Cerclage Plus Progesterone vs Progesterone Alone in Twin Short CervixRecruitingNot applicableNational Hospital of Obstetrics and GynecologyNCT07372495Written as Progesterone
- Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm BirthNot yet recruitingNot applicableNingbo UniversityNCT07415070Written as Vaginal Progesterone
- Cerclage With Progesterone Versus Progesterone Only in Singleton PregnanciesRecruitingNot applicableMỹ Đức HospitalNCT06463652Written as Vaginal progesterone
- Nintedanib for Improving Reproductive Outcomes in AdenomyosisNot yet recruitingPhase 3Sun Yat-sen UniversityNCT07162961Written as Progesterone
- Androgen Blockade and Progesterone Augmentation of Gonadotropin SecretionRecruitingEarly Phase 1University of VirginiaNCT04597099Written as Micronized progesterone
- Late-Start Corifollitropin Alfa in Mild Ovarian StimulationCompletedNot applicableAssisting NatureNCT07891793Written as Progesterone
- Rhythmic Estradiol and Bone HealthCompletedPhase 4Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT05903820Written as Progesterone
- Estrogen Variability and Irritability During the Menopause TransitionCompletedPhase 4University of North Carolina, Chapel HillNCT05388656Written as Progesterone 200 mg
- Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)CompletedPhase 3EstetraNCT04209543Written as Progesterone
- Addition of Gonadotropin Releasing Hormone Agonist to Luteal Phase SupportCompletedPhase 4Alexandria UniversityNCT05286554Written as Progesterone
- To Investigate Efficacy and Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as ReferenceCompletedPhase 3Changchun GeneScience Pharmaceutical Co., Ltd.NCT06091436Written as Progesterone
- A Study to Investigate the Efficacy and Safety of a Single Injection of Corifollitropin Alfa (Organon 36286) for Ovarian Stimulation Using Daily Recombinant Follicle Stimulating Hormone (FSH) as Reference (P05787)CompletedPhase 3Organon and CoNCT00696800Written as Progesterone
- Corifollitropin Alfa in Participants Undergoing Repeated Controlled Ovarian Stimulation (COS) Cycles Using a Multiple Dose Gonadatropin Releasing Hormone (GnRH) Antagonist Protocol (Study 38825)(P05714)CompletedPhase 3Organon and CoNCT00696878Written as Progesterone
- To Investigate Efficacy and Safety of a Single Injection of Org 36286 for Ovarian Stimulation Using Daily Recombinant FSH as Reference (Ensure)(P05690/MK-8962-001)CompletedPhase 3Organon and CoNCT00702845Written as progesterone
- Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short CervixCompletedPhase 4Thomas Jefferson UniversityNCT03251729Written as Vaginal progesterone
Showing 20 of 46.
As the comparator · 22 — what is tested is compared with Progesterone
- Oral GnRH Antagonist (Linzagolix) Versus Injectable GnRH Antagonist in Controlled Ovarian Stimulation for In Vitro Fertilization: A Randomized Controlled Non-Inferiority Trial With a Concurrent Comparator Cohort Undergoing Progestin-Primed Ovarian Stimulation (PPOS)Not yet recruitingNot applicableCentro A.M.B.R.A. (Associazione Medici e Biologi per la Riproduzione Assistita)NCT07732348Written as Medroxyprogesterone Acetate ; Micronized Progesterone
- Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase SupportRecruitingPhase 1ART Fertility Clinics LLCNCT05969795Written as Progesterone 100 Mg Vaginal Insert
- Verify the Safety and Effectiveness of the Cerclage Pessary in Prevention and Treatment of High-risk Preterm PregnancyNot yet recruitingNot applicableQH Medical Technology Ltd.NCT03637062Written as Progesterone
- Natural Versus Artificial Cycle for Frozen-Thawed Embryo TransferCompletedPhase 4Universitaire Ziekenhuizen KU LeuvenNCT03642665Written as Micronized progesterone
- Non-surgical Interventions for Infertility in EndometriosisCompletedPhase 2Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshNCT06560814Written as Dydrogesterone plus timed intercourse
- Oral Versus Vaginal Progesterone for Luteal Phase Supplementation in Frozen Embryo Transfer CyclesCompletedPhase 4CRG UZ BrusselNCT04758871Written as Micronized progesterone
- Two Different Types of Luteal Phase Support in Natural Cycle Frozen Embryo Transfer and Its Effect on Pregnancy RatesStatus unknownNot applicableShaare Zedek Medical CenterNCT05838105Written as Progesterone 100Mg Vag Tab
- GnRH Agonist for Luteal Phase Support.Status unknownNot applicableShaare Zedek Medical CenterNCT05484193Written as Progesterone
- Luteal Support in Frozen-Thawed Embryo Transfer CyclesCompletedPhase 4Centrum Clinic IVF CenterNCT03948022Written as Progesterone 50Mg/mL Oil
- The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF PatientsCompletedPhase 4Peter HumaidanNCT01980680Written as Progesterone and Estradiol
- Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo TransferStatus unknownNot applicableWolfson Medical CenterNCT03832699Written as Endometrin 100Mg Vaginal Insert
- Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer CyclesStatus unknownPhase 4Memorial Sisli Hospital, IstanbulNCT04124913Written as Progesterone Vaginal Gel [Crinone]
- Programmed Death-1(PD-1) Inhibitor Combined With Progesterone Treatment in Endometrial CancerStatus unknownEarly Phase 1Shanghai First Maternity and Infant HospitalNCT04046185Written as progesterone
- Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm DeliveryCompletedPhase 2Grünenthal GmbHNCT02225353Written as Progesterone 200 mg vaginal capsules
- Implantation Enhancement by Elective Cryopreservation of All Viable EmbryosCompletedNot applicableUniversitair Ziekenhuis BrusselNCT02148393Written as Utrogestan®
- Progesterone and Doppler in Recurrent AbortionStatus unknownPhase 4Assiut UniversityNCT03267771Written as Progesterone Suppositories Vaginal
- Vaginal Administration of ALA vs Progesterone for the Subchorionic Hematoma TreatmentCompletedPhase 4Azienda USL FerraraNCT02601898Written as Progesterone
- Cervical Pessary vs Vaginal Progesterone in Preventing Preterm Birth Among Women Presenting With Short Cervix: An Open-label Randomized Controlled TrialStatus unknownPhase 2/3Hillel Yaffe Medical CenterNCT02470676Written as Progesterone
- A Study Using Micronised Progesterone (Crinone® 8%) in the Luteal Phase Support of Women Undergoing in Vitro Fertilisation (IVF) and Embryo Transfer (ET)CompletedPhase 3Merck KGaA, Darmstadt, GermanyNCT01081652Written as Progesterone
- Comparison of DR-2011 to a Progesterone Vaginal Gel for Luteal Phase ReplacementCompletedPhase 2Duramed ResearchNCT00117468Written as Progesterone 8% Vaginal Gel
Showing 20 of 22.
Codes
What other systems call Progesterone · ClinicalTrials.gg INT008101
- MeSH (NLM) D011374ProgesteroneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 4G7DS2Q64YPROGESTERONEConfirmed NLM, Wikidata
- RxNorm 8727Confirmed FDA, Wikidata
- Wikidata Q26963progesteroneConfirmed NLM, Wikidata
- NCI Thesaurus C777Therapeutic ProgesteroneOne source FDA
- DrugBank DB00396One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011374 | Progesterone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 4G7DS2Q64Y | PROGESTERONE | Confirmed NLM, Wikidata |
| RxNorm | 8727 | — | Confirmed FDA, Wikidata |
| Wikidata | Q26963 | progesterone | Confirmed NLM, Wikidata |
| NCI Thesaurus | C777 | Therapeutic Progesterone | One source FDA |
| DrugBank | DB00396 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.