An interventional study of Video/Brochure and Video/Brochure/Follow-up Call in Lung Cancer Screening, sponsored by Johns Hopkins University. Not yet recruiting. Open to participants aged 50 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-11-02.
Sponsored by Johns Hopkins University · Not applicable, Interventional, and Screening
This study is a three-arm, randomized controlled pilot of a lung cancer screening intervention. The investigators will recruit participants ages 50-80 who are likely to meet lung cancer screening guidelines. After eligibility screening, participants will be randomized to one of three educational interventions regarding lung cancer. Lung cancer screening outcomes will be assessed.
Smoking is associated with a dramatically increased risk of lung cancer, with rates 10-40 times higher among those who smoke than among those who do not smoke, with smoking accounting for about 85-90% of all lung cancer cases. Screening for lung cancer with low-dose computed tomography (LDCT) has been shown to significantly reduce lung cancer mortality in high-risk populations. Lung cancer screening with annual LDCT is therefore recommended by the US Preventive Services Task Force (USPSTF) for all adults aged 50 to 80 years with a 20 pack-year history of smoking who currently smoke or have quit within the past 15 years. However, in a nationwide study of individuals eligible for lung cancer screening in 2022, only 18% were up-to-date with the recommended screening.
The investigators propose a three-arm, randomized controlled pilot of a lung cancer screening intervention. Recruitment will be carried out primarily through the electronic health record, with invitations sent to patients aged 50-80 who have a documented history of smoking but no chest CT on file within the past 18 months. The investigators will also partner with community organizations such as senior centers and churches to distribute information about the study.
Potential participants will be screened for eligibility for lung cancer screening. If eligible, the participants will undergo a consent process, complete baseline surveys (demographics, etc.), and be randomized to one of the following three study conditions:
Three months after receiving the intervention, follow-up surveys will be sent to assess attitudes toward and completion of lung cancer screening.
1,509 studies on the registry are indexed under Smoking; 193 are open to participants now.
This study's planned enrollment of 300 is above the median of 115 across 1,164 interventional studies indexed under Smoking.
Browse Smoking studies →Johns Hopkins University is the lead sponsor of 1,815 studies on the registry; 315 are open to participants now.
Of its 208 completed or terminated interventional studies of FDA-regulated products, 144 (69%) have results posted.
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Exclusion Criteria:
Participants receive notification of eligibility for lung cancer screening with a recommendation to discuss with their health care provider
Participants receive an animated video with accompanying guide.
Behavioral: Video/Brochure
Participants receive an animated video video, an accompanying guide, and a call with a community outreach specialist/community health worker.
Behavioral: Video/Brochure/Follow-up Call
Brief animated video that covers the basics of lung cancer screening and shows shared decision-making. An accompanying brochure uses images and information from the video to reinforce concepts (delivered via PDF or mail, per participant preference).
Brief animated video that covers the basics of lung cancer screening and shows shared decision-making. An accompanying brochure uses images and information from the video to reinforce concepts (delivered via PDF or mail, per participant preference). A follow-up call with a community outreach specialist/community health worker is made 1-2 weeks after the initial intervention to check in on participant plans regarding lung cancer screening and to assist with any barriers.
Number of Participants with Completion of Lung Cancer Screening
Self-reported completion of low dose chest CT for lung cancer screening during the study follow-up period
Time frame: 3 months
Number of Participants with Clinician Discussion on Lung Cancer Screening
Self-reported conversation with clinician about lung cancer screening during the study follow-up period
Time frame: 3 months
Number of Participants with Change in Intent to obtain lung cancer screening
Change in intent to obtain lung cancer screening
Time frame: 3 months
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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